Best TWAS P=1.47e-11 · Best GWAS P=3.08e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Brain Lower Grade Glioma | IRX6 | 0.05 | 0.04 | lasso | 5 | 0.04 | 1.5e-05 | 6.9 | 6.8 | 1.5e-11 | 0.95 | 0.00 | 1.00 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | IRX6 | 0.02 | 0.02 | lasso | 3 | 0.03 | 1.7e-04 | -6.8 | 6.6 | 3.4e-11 | 0.83 | 0.01 | 0.93 | FALSE |