TWAS hub - IRX6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Brain Lower Grade Glioma	0.0454	0.0210	5.2e-05	0.036	0.034	0.039	NA	0.041	5.6e-05	9.4e-05	2.5e-05	NA	1.5e-05
2	TCGA	Lung Squamous Cell Carcinoma	0.0239	0.0136	6.8e-03	0.021	0.018	0.028	NA	0.031	1.6e-03	3.3e-03	3.5e-04	NA	1.7e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Loneliness, isolation	8.2	11.3	11.4	3.4	3.3
Alzheimer’s Disease (in father)	6.8	7.4	8.6	2.9	2.5
Blood Red Count	4.6	44.8	45.6	6.8	6.6
HbA1C	4.4	4.9	5.4	-2.1	-2.3
Multivitamins +/- minerals	3.9	5.0	6.7	-2.6	-1.8
Average weekly beer plus cider intake	3.9	5.7	8.7	-3.0	-1.6
Medication: Atenolol	3.5	4.4	5.1	1.9	2.3
Glaucoma (self-reported)	3.3	3.9	5.9	1.3	2.4
Depression (self-reported)	3.2	3.8	6.2	2.5	1.2
Ever had prostate specific antigen (PSA) test	3.2	3.6	4.3	-2.1	-1.7
Vitamin and mineral supplements	3.1	4.2	5.6	2.4	1.7
Heart disease (mother)	3.0	3.7	5.3	2.3	1.4
Medication: Levothyroxine sodium	2.8	4.7	5.3	-2.0	-2.3
Fed-up feelings	2.7	5.0	5.2	2.2	2.3
Comparative body size at age 10	2.6	7.1	7.3	2.7	2.6
Frequency of tenseness / restlessness in last 2 weeks	2.4	3.7	4.4	2.1	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.1	3.1	1.8	1.8
Hypothyroidism/myxoedema (self-reported)	2.3	4.4	5.0	-1.9	-2.2
Medication: Gliclazide	2.3	2.7	3.4	1.4	1.8
Forced vital capacity (FVC)	2.2	8.5	13.4	-3.7	-1.9
Serious illness, injury or assault of a close relative in last 2 years	2.2	2.5	3.6	1.9	1.1
Ulcerative Colitis	2.1	3.1	4.0	2.0	1.5
Depressed Affect (Nagel 2018)	2.0	4.3	5.9	1.6	2.4
Neuroticism (Nagel 2018)	2.0	4.6	6.1	1.8	2.5
Lupus	2.0	3.1	4.5	-2.1	-1.3
Neuroticism	2.0	4.9	5.1	2.3	2.1
Frequency of depressed mood in last 2 weeks	2.0	2.8	3.5	1.9	1.4
Medication: Ibuprofen (e.g. Nurofen)	2.0	2.5	3.1	1.8	1.4
Exposure to tobacco smoke at home	2.0	2.2	3.1	1.8	1.2
Tinnitus: Yes, now most or all of the time	2.0	2.3	3.4	-1.8	-1.1
Townsend deprivation index at recruitment	1.9	2.7	4.5	2.1	0.9
Heel bone mineral density (BMD) T-score, automated (left)	1.9	4.4	5.4	1.8	2.3
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.3	5.1	1.9	2.3
Number of full sisters	1.9	2.4	3.2	-1.3	-1.8
Heart disease (siblings)	1.9	2.4	2.5	1.5	1.6
Rheumatoid Arthritis	1.8	2.5	3.0	-1.4	-1.7
Number of full brothers	1.8	2.3	2.4	-1.5	-1.6
Medication: Ibuprofen	1.8	2.2	2.6	1.6	1.4
Suffer from ‘nerves’	1.8	2.9	3.8	1.9	1.4
Commuting to job workplace: Car/motor vehicle	1.8	2.1	2.9	1.1	1.7
Heel T-Score	1.7	13.3	15.4	3.3	3.9
Financial difficulties in last 2 years	1.6	2.2	3.1	1.1	1.8
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	2.7	1.7	1.2
Eye problems/disorders: None of the above	1.6	1.9	3.7	0.2	-1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.8	2.0	1.4	1.3
Heart attack/myocardial infarction (self-reported)	1.6	2.0	2.1	1.4	1.4
Worry (Nagel 2018)	1.5	3.1	3.6	1.9	1.6
Type 2 Diabetes (T2D) (2012)	1.5	1.8	3.3	1.8	0.5
Average weekly spirits intake	1.5	1.9	3.3	-1.8	-0.7
Smoking status: Previous	1.5	2.2	2.7	-1.6	-1.3
Osteoporosis (self-reported)	1.5	1.9	2.8	1.0	1.7
Age started oral contraceptive pill	1.5	1.8	2.6	1.6	1.0
Hypothyroidism (self reported)	1.4	3.2	3.3	-1.7	-1.8
High blood pressure (mother)	1.4	2.0	2.4	-1.5	-1.3
Waist circumference	1.4	5.0	5.3	2.1	2.3
Chest pain or discomfort	1.4	2.0	2.1	1.4	1.5
Guilty feelings	1.4	2.1	2.8	1.2	1.7
Alcohol drinker status: Never	1.4	1.7	2.3	1.5	1.0
Waist Hip Ratio (WHR)	1.3	5.7	6.6	2.6	2.2
Diabetes (self-reported)	1.3	1.9	2.8	1.0	1.7
Forced expiratory volume in 1-second (FEV1)	1.3	4.3	7.2	-2.7	-1.2
Breastfed as a baby	1.3	1.6	1.9	1.1	1.4
Back pain experienced in last month	1.3	2.0	2.3	1.5	1.3
Nervous feelings	1.2	2.2	3.2	1.8	1.1
Heart attack	1.2	1.5	1.7	1.1	1.3
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	2.1	-1.3	-1.5
Forced vital capacity (FVC), Best measure	1.2	4.3	6.6	-2.6	-1.4
Pulse rate, automated reading	1.2	3.8	4.3	2.1	1.8
Alzheimer’s Disease (including proxy)	1.1	1.6	2.2	1.0	1.5
Mean Putamen Volume	1.1	1.3	1.6	1.3	1.0
Hand grip strength (right)	1.1	3.1	5.0	-2.2	-1.1
Medication: Amlodipine	1.1	1.6	2.8	-0.6	-1.7
Illnesses of siblings: Diabetes	1.1	1.4	2.2	-0.7	-1.5
Hearing aid user	1.1	1.2	1.9	-0.7	-1.4
Neuroticism score	1.0	2.0	2.1	1.4	1.4
Birth weight	1.0	2.2	3.8	0.9	1.9
Qualifications: nursing, teaching	1.0	1.5	1.6	-1.3	-1.2
LDL Cholesterol	0.9	1.5	2.5	-1.6	-0.7
Smoking Status	0.9	2.2	2.2	-1.5	-1.5
Mouth/teeth dental problems	0.9	1.4	2.4	-1.6	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	1.3	1.1	1.1
Medication: Ventolin 100micrograms inhaler	0.9	1.1	1.8	1.3	0.6
High blood pressure (siblings)	0.9	1.3	1.7	-1.3	-0.9
Health satisfaction	0.9	1.2	1.2	-1.1	-1.1
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.2	-0.2	-1.5
Leg fat percentage (left)	0.9	3.1	3.9	1.5	2.0
Alcohol drinker status: Previous	0.9	1.0	1.1	0.9	1.0
Depression (Nagel 2018)	0.8	1.3	2.0	1.4	0.7
Schizophrenia vs Biploar Disorder	0.8	1.0	1.6	-0.7	-1.3
Crohns Disease (2017)	0.8	1.8	2.2	1.5	1.2
Hand grip strength (left)	0.8	2.2	3.5	-1.9	-0.9
Hearing difficulty/problems: Yes	0.8	1.2	1.8	-1.3	-0.8
Medication: Metformin	0.8	1.1	1.6	0.8	1.3
Relative age voice broke	0.8	1.3	2.3	0.5	1.5
Stomach or abdominal pain in last month	0.8	1.0	1.7	-1.3	-0.5
Past tobacco smoking	0.8	1.4	1.7	1.3	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.5	4.1	-2.0	-0.9
Peak expiratory flow (PEF)	0.8	1.9	3.3	-1.8	-0.7
Leg fat mass (left)	0.8	3.2	3.8	1.6	1.9
Age at First Birth	0.7	1.0	1.1	-1.0	-1.0
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	0.9	-0.9	-0.8
Serious illness, injury or assault to yourself	0.7	0.9	1.8	-1.3	-0.2
Pulse wave Arterial Stiffness index	0.7	0.8	1.3	1.1	0.6
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	1.9	-0.7	-1.4
Pulse wave peak to peak time	0.7	0.9	1.4	-1.2	-0.6
Emphysema/chronic bronchitis	0.7	0.8	1.3	0.6	1.1
Leg pain on walking	0.7	0.9	1.0	0.9	1.0
Medication: Aspirin	0.7	0.9	1.1	0.9	1.0
Diabetes diagnosed by doctor	0.7	1.1	1.6	0.8	1.3
Miserableness	0.7	1.1	1.8	0.7	1.3
Myopia	0.7	1.0	2.1	-0.1	-1.4
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	1.3	-1.1	-0.6
Irritable Bowel Disease (IBD)	0.6	1.5	2.3	1.5	0.8
Average weekly fortified wine intake	0.6	0.7	1.0	0.6	1.0
Qualifications: CSEs or equivalent	0.6	0.7	1.1	-0.6	-1.1
Pain all over the body in last month	0.6	0.6	0.8	-0.9	-0.7
Prospective memory result	0.6	0.7	0.8	0.9	0.7
Leg fat percentage (right)	0.6	2.2	2.8	1.2	1.7
Exposure to tobacco smoke outside home	0.6	0.8	1.6	-1.3	-0.1
Medication: Blood pressure	0.6	1.0	1.2	1.1	0.9
Leg fat mass (right)	0.6	2.4	3.0	1.4	1.7
Age at last live birth	0.6	0.8	1.6	1.3	0.1
Alzheimer’s Disease (in mother)	0.5	0.5	1.1	-1.0	0.0
Systolic Blood Pressure	0.5	2.3	2.5	-1.6	-1.4
Relative age of first facial hair	0.5	1.0	1.5	0.7	1.2
Pack years adult smoking proportion	0.5	0.7	1.0	-0.6	-1.0
Alcohol usually taken with meals	0.5	0.8	1.1	0.7	1.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	0.8	-0.7	-0.9
Impedance of arm (left)	0.5	2.2	2.4	-1.6	-1.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	0.8	-0.9	-0.6
Headache pain in last month	0.5	0.8	1.1	0.7	1.1
Medication for pain relief, constipation, heartburn	0.5	0.8	1.0	-0.8	-1.0
Medication: Omeprazole	0.5	0.6	1.3	-1.1	-0.2
Whole body fat mass	0.5	2.1	2.7	1.2	1.6
Average weekly red wine intake	0.5	0.7	1.2	-0.4	-1.1
Mood swings	0.5	0.8	1.3	0.6	1.1
Long-standing illness, disability or infirmity	0.5	0.8	1.3	0.5	1.1
Commuting to job workplace: Walk	0.5	0.5	0.7	-0.6	-0.8
Mineral and other dietary supplements	0.5	0.7	1.1	0.5	1.1
Illnesses of father: None of the above (group 1)	0.5	0.6	1.0	-1.0	-0.5
Mother’s age at death	0.5	0.6	0.8	0.7	0.9
Pain type(s) experienced in last month: Hip pain	0.5	0.7	0.9	0.9	0.6
Risk taking	0.5	0.8	1.1	0.7	1.0
Unable to work because of sickness or disability	0.5	0.6	1.1	1.0	0.4
Pack years of smoking	0.5	0.7	1.0	-0.7	-1.0
Ulcerative Colitis (UC)	0.4	0.7	1.1	1.0	0.5
Body Mass Index (BMI) (2010)	0.4	0.6	0.9	1.0	0.5
Coronary Artery Disease (CAD)	0.4	0.5	0.9	-0.2	-1.0
HDL Cholesterol	0.4	0.7	1.1	0.5	1.0
Neuroticism (2016)	0.4	0.6	1.1	1.1	-0.4
Triglycerides	0.4	0.7	0.9	0.7	0.9
Respiratory disease	0.4	0.9	1.0	-1.0	-0.8
Lung FEV1/FVC ratio	0.4	2.3	3.4	1.0	1.9
Number of treatments/medications taken	0.4	0.7	0.9	0.9	0.7
Sensitivity / hurt feelings	0.4	0.6	1.1	0.4	1.0
Systolic blood pressure, automated reading	0.4	1.1	1.1	-1.0	-1.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	0.9	-0.9	0.3
Medication for hormone replacement therapy	0.4	0.5	0.8	0.4	0.9
Trunk fat mass	0.4	1.5	2.2	1.0	1.5
Hearing difficulty/problems with background noise	0.4	0.6	0.9	0.6	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	0.9	1.0	0.6
Number of live births	0.4	0.5	0.5	-0.7	-0.7
Medication: Lansoprazole	0.4	0.5	0.9	-0.4	-0.9
Pulse wave reflection index	0.4	0.4	0.8	-0.3	-0.9
Gout (self-reported)	0.4	0.5	0.5	0.7	0.7
Body fat percentage	0.4	1.5	2.0	1.0	1.4
Number of children fathered	0.4	0.5	0.9	0.0	1.0
Qualifications: College or University degree	0.4	1.3	1.5	-1.2	-1.1
Medication: Seretide 50 evohaler	0.4	0.4	0.8	0.1	0.9
Had major operations	0.4	0.5	0.6	-0.7	-0.8
Eye problems/disorders: Cataract	0.4	0.4	0.8	-0.2	0.9
Number of self-reported non-cancer illnesses	0.4	0.6	0.7	0.8	0.8
Eye problems/disorders: Glaucoma	0.4	0.5	0.6	-0.6	0.8
Fractured/broken bones in last 5 years	0.4	0.5	0.9	-0.2	-1.0
Ever depressed for a whole week	0.4	0.5	0.6	-0.8	-0.6
Primary Biliary Cirrhosis	0.3	0.5	0.9	0.3	0.9
Lung FVC	0.3	1.8	3.5	-1.9	-0.1
Supplements: Zinc	0.3	0.4	0.6	-0.4	-0.8
Severe depression (siblings)	0.3	0.3	0.5	-0.7	-0.3
Trunk fat percentage	0.3	1.2	1.8	0.7	1.4
Maternal smoking around birth	0.3	0.5	0.9	0.3	1.0
Taking other prescription medications	0.3	0.5	0.9	0.2	1.0
Body mass index (BMI)	0.3	1.2	1.4	1.0	1.2
Had menopause	0.3	0.4	0.4	0.6	0.6
Alcohol intake versus 10 years previously	0.3	0.5	0.8	-0.5	-0.9
Pulse rate	0.3	0.6	0.8	0.6	0.9
Happiness	0.3	0.4	0.8	-0.1	-0.9
Medication: Cholesterol lowering	0.3	0.4	0.7	-0.3	0.8
Hair/balding pattern: Pattern 4	0.3	0.6	0.7	0.7	0.8
Loud music exposure frequency	0.3	0.4	0.7	0.8	-0.1
Medication: Paracetamol	0.3	0.5	0.6	0.7	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.4	-0.5	-0.6
Shortness of breath walking on level ground	0.3	0.3	0.6	-0.1	-0.8
Medication: Allopurinol	0.3	0.4	0.5	0.6	0.7
Alcohol intake frequency.	0.3	0.7	1.3	1.1	0.4
Family relationship satisfaction	0.3	0.3	0.5	0.4	-0.7
Knee pain experienced in last month	0.3	0.4	0.7	0.8	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.4	-0.6	-0.6
Medication: Paracetamol	0.3	0.4	0.4	0.6	0.6
Medication: Lisinopril	0.3	0.4	0.5	-0.7	-0.5
Number of operations (self-reported)	0.3	0.5	0.7	-0.5	-0.9
Pain experienced in last month	0.3	0.5	0.6	-0.8	-0.7
Major Depression (MDD)	0.2	0.2	0.3	-0.3	-0.6
Bipolar Disorder (2011)	0.2	0.2	0.3	0.0	-0.6
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.5	0.5	0.7
Hair Pigment	0.2	4.5	5.2	-2.0	-2.3
Diabetes (father)	0.2	0.2	0.4	-0.1	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.5	0.7	0.0
Hayfever, allergic rhinitis or eczema	0.2	0.5	0.7	0.6	0.8
Sitting height	0.2	1.4	2.5	1.6	0.6
Chronic bronchitis/emphysema (father)	0.2	0.3	0.4	-0.4	-0.6
Illnesses of siblings	0.2	0.3	0.5	0.4	0.7
Impedance of arm (right)	0.2	1.0	1.0	-1.0	-1.0
Arm fat percentage (right)	0.2	0.8	0.8	0.8	0.9
Hip circumference	0.2	0.8	1.5	0.4	1.2
Father’s age at death	0.2	0.2	0.4	-0.2	-0.6
Hair/balding pattern: Pattern 3	0.2	0.3	0.5	-0.7	-0.4
Arm fat mass (right)	0.2	1.0	1.2	0.9	1.1
Tense / ‘highly strung’	0.2	0.3	0.6	0.7	0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.3	0.5	0.5
Blood clot in the leg (DVT)	0.2	0.3	0.3	-0.5	-0.5
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.3	-0.6	-0.3
Age at first live birth	0.2	0.4	0.7	0.8	-0.0
Migraine (self-reported)	0.2	0.3	0.6	-0.1	0.7
Illnesses of father: Heart disease	0.2	0.3	0.5	0.7	0.2
Arm fat percentage (left)	0.2	0.7	0.9	0.7	0.9
Friendships satisfaction	0.2	0.3	0.5	-0.1	-0.7
Medication for cholesterol	0.2	0.3	0.5	0.7	0.1
Breast cancer (self-reported)	0.2	0.3	0.5	-0.2	-0.7
Osteoarthritis (self-reported)	0.2	0.2	0.4	0.6	-0.3
Arm fat mass (left)	0.2	0.8	1.0	0.8	1.0
Ever taken oral contraceptive pill	0.2	0.2	0.3	-0.2	-0.6
Commuting to job workplace: Public transport	0.2	0.2	0.4	-0.0	-0.6
Medication: Atorvastatin	0.2	0.3	0.6	-0.7	-0.0
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.3	-0.1	0.5
Breast Cancer	0.1	0.1	0.3	0.5	0.0
Ovarian Cancer	0.1	0.1	0.2	-0.4	-0.2
Fasting Glucose	0.1	0.1	0.2	-0.0	0.4
Schizophrenia (2014)	0.1	0.2	0.3	0.5	-0.2
Blood Platelet Count	0.1	1.5	2.7	0.5	1.6
BMI	0.1	0.6	0.8	0.9	0.6
Allergy or Eczema	0.1	0.3	0.4	0.5	0.7
Cardiovascular Disease	0.1	0.2	0.4	-0.7	-0.3
Chronotype (morning person)	0.1	0.3	0.3	-0.5	-0.5
Diabetes (mother)	0.1	0.1	0.2	0.1	0.5
Leg fat-free mass (left)	0.1	0.3	0.4	0.6	0.5
Age when periods started (menarche)	0.1	0.1	0.2	-0.1	-0.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	-0.4	0.3
Supplements: Glucosamine	0.1	0.2	0.3	-0.2	-0.5
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	-0.0	0.4
Leg predicted mass (left)	0.1	0.4	0.4	0.7	0.5
Number of incorrect matches in round	0.1	0.1	0.3	-0.1	-0.5
Hair/balding pattern: Pattern 2	0.1	0.2	0.3	0.2	0.5
Had other major operations	0.1	0.2	0.3	-0.2	-0.6
Allergy	0.1	0.3	0.5	-0.3	-0.7
Medication: Ramipril	0.1	0.1	0.1	0.4	-0.1
Medication: Simvastatin	0.1	0.1	0.2	-0.0	0.5
Weight	0.1	0.4	0.7	0.4	0.8
Time employed in main current job	0.1	0.2	0.2	-0.5	-0.3
Falls in the last year	0.1	0.1	0.2	0.2	0.4
Noisy workplace	0.1	0.1	0.1	-0.4	-0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.3	0.1	-0.6
Asthma	0.1	0.2	0.3	-0.6	-0.2
Illnesses of mother	0.1	0.1	0.2	0.1	-0.4
Arm fat-free mass (right)	0.1	0.7	0.8	0.7	0.9
Worry too long after embarrassment	0.1	0.1	0.2	-0.4	0.3
Neck or shoulder pain in last month	0.1	0.1	0.3	-0.5	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	-0.5	0.1
Arm predicted mass (right)	0.1	0.6	0.8	0.6	0.9
Comparative height size at age 10	0.1	0.7	0.7	0.8	0.8
Overall health rating	0.1	0.3	0.6	0.8	-0.2
Supplements: Vitamin C	0.1	0.1	0.2	-0.4	0.2
Hypertension (Self-reported)	0.1	0.1	0.2	0.4	0.3
Leg fat-free mass (right)	0.1	0.3	0.3	0.6	0.5
Ever had bowel cancer screening	0.1	0.1	0.1	-0.3	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.2	0.1	0.4
Smoking status: Current	0.1	0.1	0.2	-0.2	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.6	-0.1	0.8
Wears glasses or contact lenses	0.1	0.1	0.2	-0.2	0.5
Financial situation satisfaction	0.1	0.1	0.2	-0.3	0.4
Medication: Blood pressure	0.1	0.2	0.4	0.1	0.6
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.2	-0.3	-0.4
Illnesses of father: High blood pressure	0.1	0.2	0.3	-0.6	0.1
Basal metabolic rate	0.1	0.3	0.4	0.5	0.6
Arm fat-free mass (left)	0.1	0.4	0.4	0.6	0.7
Irritability	0.1	0.1	0.3	0.5	0.1
Commuting to job workplace: Cycle	0.1	0.1	0.2	-0.1	-0.5
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.3	-0.5	-0.6
Cholesterol lowering medication	0.1	0.1	0.2	0.2	0.5
Supplements: Calcium	0.1	0.1	0.2	-0.1	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.1	0.1	-0.4
Impedance of whole body	0.1	0.5	0.8	-0.9	-0.5
Bipolar Disorder (2018)	0.0	0.0	0.0	-0.1	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.2	-0.1
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.1	-0.3	-0.2
Schizophrenia (2018)	0.0	0.1	0.1	0.3	-0.2
Reaction Time	0.0	0.0	0.0	-0.1	0.0
Prostate Cancer	0.0	0.1	0.1	-0.2	0.3
Crohns Disease (2012)	0.0	0.0	0.0	0.2	0.0
Blood Eosinophil Count	0.0	0.4	0.6	-0.4	-0.7
Blood White Count	0.0	0.4	0.5	0.4	0.7
Height	0.0	0.9	1.5	-1.2	-0.6
Tanning	0.0	0.1	0.1	-0.3	0.2
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.1	0.3	-0.0
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.0	0.0	0.2
Ever had hysterectomy (womb removed)	0.0	0.1	0.1	0.3	-0.2
Angina	0.0	0.0	0.0	-0.0	-0.1
Medication: Co-codamol	0.0	0.0	0.1	-0.0	-0.2
Impedance of leg (right)	0.0	0.1	0.1	-0.4	0.2
Current tobacco smoking	0.0	0.1	0.1	0.1	-0.4
High blood pressure	0.0	0.1	0.1	0.3	0.4
Impedance of leg (left)	0.0	0.1	0.2	-0.2	0.4
Qualifications: None of the above	0.0	0.1	0.2	-0.4	-0.1
Fluid intelligence score	0.0	0.0	0.0	-0.2	0.2
Trunk fat-free mass	0.0	0.2	0.2	0.4	0.4
Worrier / anxious feelings	0.0	0.0	0.0	0.2	0.2
Mouth/teeth dental problems: Dentures	0.0	0.1	0.1	-0.3	-0.2
Lung cancer (father)	0.0	0.0	0.0	0.1	0.1
Trunk predicted mass	0.0	0.1	0.1	0.4	0.3
Standing height	0.0	0.4	0.7	-0.8	-0.4
Length of working week for main job	0.0	0.0	0.0	-0.2	-0.0
Birth weight of first child	0.0	0.0	0.0	0.0	-0.0
Wheeze or whistling in the chest in last year	0.0	0.1	0.1	-0.1	0.4
Angina (self-reported)	0.0	0.0	0.0	-0.1	-0.0
Mean time to correctly identify matches	0.0	0.0	0.0	-0.0	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.1	-0.3	-0.1
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.0	-0.1	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.2	-0.4	0.1
Whole body fat-free mass	0.0	0.3	0.3	0.5	0.5
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.1	-0.2	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.0	0.1	0.1	0.3	-0.1
Asthma (self-reported)	0.0	0.1	0.2	-0.4	-0.2
Medication: Aspirin	0.0	0.1	0.1	0.2	0.3
Whole body water mass	0.0	0.2	0.2	0.4	0.4
Leg predicted mass (right)	0.0	0.2	0.2	0.5	0.4
Average weekly champagne plus white wine intake	0.0	0.0	0.0	0.0	0.0
High cholesterol (Self-reported)	0.0	0.1	0.1	0.3	0.2
Medication: Bendroflumethiazide	0.0	0.1	0.1	0.1	-0.3
Ever smoked	0.0	0.0	0.0	-0.0	0.2
Diastolic blood pressure, automated reading	0.0	0.0	0.0	0.0	-0.2
Basal cell carcinoma (self-reported)	0.0	0.0	0.0	0.1	0.2
Arm predicted mass (left)	0.0	0.2	0.3	0.4	0.6

Hub : Genes

IRX6

Models

Trait associations