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chr17:70,490,888-71,940,218

Best TWAS P=3.75e-10 · Best GWAS P=1.65e-09 conditioned to 0.407

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells Transformed fibroblasts	C17orf80	0.10	0.10	lasso	5	0.10	1.2e-07	5.5	-5.7	1.2e-08	-0.99	0.03	0.97	FALSE
2	GTEx	Colon Sigmoid	C17orf80	0.30	0.17	enet	10	0.11	9.1e-05	5.9	-5.6	1.9e-08	-0.99	0.02	0.97	FALSE
3	GTEx	Esophagus Muscularis	C17orf80	0.13	0.00	lasso	7	0.00	2.4e-01	5.8	-6.0	2.3e-09	-0.86	0.03	0.86	FALSE
4	GTEx	Testis	FAM104A	0.22	0.11	lasso	6	0.14	9.8e-07	5.8	-5.4	7.6e-08	-0.94	0.02	0.98	FALSE
5	GTEx	Testis	COG1	0.21	0.26	lasso	2	0.25	1.8e-11	5.7	-5.7	1.1e-08	-0.98	0.03	0.97	FALSE
6	GTEx	Thyroid	COG1	0.16	0.12	lasso	3	0.13	5.1e-10	5.1	5.4	7.3e-08	0.97	0.02	0.98	FALSE
7	YFS	Blood	FAM104A	0.06	0.06	enet	15	0.06	5.5e-18	5.9	-5.9	3.3e-09	-1.00	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C17orf80	0.04	0.04	enet	3	0.05	4.2e-05	5.7	-5.4	5.5e-08	-0.96	0.02	0.97	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	C17orf80	0.04	0.09	enet	10	0.10	5.2e-19	5.8	-5.8	8.4e-09	-0.99	0.02	0.98	FALSE
10	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C17orf80	0.07	0.03	enet	6	0.05	1.1e-03	5.3	-5.7	1.2e-08	-0.90	0.02	0.97	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	C17orf80	0.11	0.08	blup	52	0.07	1.2e-04	5.5	-5.1	2.8e-07	-0.96	0.03	0.97	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C17orf80	0.04	0.04	lasso	3	0.03	1.6e-04	6.0	-6.0	1.5e-09	-0.99	0.01	0.98	FALSE
13	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C17orf80	0.10	0.16	lasso	2	0.14	1.1e-08	5.9	-6.0	2.6e-09	-0.97	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	C17orf80	0.02	0.02	lasso	2	0.01	1.9e-02	5.9	-5.9	3.1e-09	-0.97	0.01	0.83	FALSE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C17orf80	0.06	0.09	blup	49	0.09	6.7e-11	5.5	-6.0	2.6e-09	-0.95	0.03	0.97	FALSE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C17orf80	0.06	0.09	enet	6	0.08	6.0e-06	5.1	-5.5	4.2e-08	-0.98	0.04	0.96	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C17orf80	0.13	0.14	lasso	3	0.15	1.1e-06	4.5	-5.2	2.6e-07	-0.95	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Soft Tissue Sarcoma	C17orf80	0.06	0.04	blup	49	0.04	1.8e-03	6.0	-6.3	3.7e-10	-0.91	0.01	0.72	TRUE
19	The Cancer Genome Atlas	Stomach Adenocarcinoma	C17orf80	0.10	0.13	lasso	3	0.12	3.1e-09	5.1	-5.6	2.5e-08	-0.92	0.03	0.97	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf80	0.06	0.12	lasso	3	0.11	4.3e-11	5.8	-5.9	3.2e-09	-0.99	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	FAM104A	0.03	0.00	blup	55	0.01	2.9e-02	5.8	6.2	4.5e-10	0.87	0.01	0.75	FALSE