Best TWAS P=3.19e-11 · Best GWAS P=1.08e-17 conditioned to 7.06e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Stomach | AC010883.5 | 0.16 | 0.07 | lasso | 6 | 0.07 | 2.4e-04 | 5.45 | -5.5 | 4.8e-08 | 0.10 | 0.33 | 0.03 | FALSE |
| 2 | GTEx | Testis | HAAO | 0.30 | 0.08 | lasso | 6 | 0.12 | 5.0e-06 | -1.11 | 6.1 | 1.3e-09 | -0.03 | 0.76 | 0.02 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ABCG5 | 0.03 | 0.01 | blup | 75 | 0.02 | 3.0e-03 | 4.17 | -5.4 | 6.1e-08 | 0.03 | 0.10 | 0.48 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PLEKHH2 | 0.07 | 0.00 | blup | 127 | 0.03 | 3.2e-04 | -0.87 | -5.6 | 1.6e-08 | -0.01 | 0.09 | 0.33 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ABCG5 | 0.05 | 0.04 | blup | 75 | 0.02 | 1.6e-03 | 6.21 | -6.6 | 3.2e-11 | 0.05 | 0.02 | 0.97 | TRUE |