TWAS hub - ABCG5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.0326	0.0151	0.00098	0.009	0.019	0.008	NA	0.005	2.9e-02	0.0030	0.0420	NA	0.0830
2	TCGA	Prostate Adenocarcinoma	0.0456	0.0205	0.00023	0.037	0.023	0.021	NA	0.022	8.1e-05	0.0016	0.0028	NA	0.0023

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
LDL Cholesterol	23.7	37.5	59.8	3.9	7.7
High cholesterol (Self-reported)	22.5	40.0	57.9	4.7	7.6
Medication: Cholesterol lowering	14.2	22.1	32.9	3.3	5.7
Medication: Simvastatin	13.8	20.3	29.4	3.4	5.4
Cholesterol lowering medication	13.7	20.2	29.6	3.3	5.4
Had other major operations	13.2	16.1	24.0	-2.9	-4.9
Number of operations (self-reported)	11.4	17.0	23.6	-3.2	-4.9
Angina	10.4	13.7	16.9	3.2	4.1
Smoking status: Previous	9.3	13.9	16.7	4.1	3.3
Angina (self-reported)	9.1	11.9	15.6	2.9	4.0
Past tobacco smoking	8.2	15.1	20.2	-4.5	-3.1
Tinnitus: Yes, but not now, but have in the past	6.5	6.9	7.5	-2.7	-2.5
Seen a psychiatrist for nerves, anxiety, tension or depression	6.2	8.0	8.1	2.9	2.8
Illnesses of father: Heart disease	6.2	8.6	9.2	2.8	3.0
Myopia	6.0	8.6	11.1	3.3	2.5
Coronary Artery Disease (CAD)	5.9	7.0	10.1	2.0	3.2
Medication: Aspirin	5.8	7.6	10.5	2.1	3.2
Medication for cholesterol, blood pressure or diabetes	5.3	8.9	11.3	-2.5	-3.4
Ever smoked	5.3	9.3	14.4	3.8	2.1
Mouth/teeth dental problems: Bleeding gums	4.7	6.1	6.8	2.3	2.6
Fasting Glucose	4.6	5.5	6.0	-2.5	-2.2
Number of full brothers	4.5	5.7	6.1	2.3	2.5
Medication: Atorvastatin	4.3	5.3	9.2	1.2	3.0
Had major operations	4.1	4.8	6.2	-1.8	-2.5
Pack years adult smoking proportion	4.0	6.2	8.8	-3.0	-1.9
Diverticular disease/diverticulitis (self-reported)	4.0	4.7	5.8	-2.4	-1.9
Blood Red Count	3.8	36.7	44.1	-5.4	-6.6
Forced vital capacity (FVC), Best measure	3.8	13.9	15.9	-4.0	-3.4
Medication: Aspirin	3.8	5.0	7.3	1.7	2.7
Cardiovascular Disease	3.4	11.1	14.4	2.8	3.8
Pack years of smoking	3.3	4.9	7.2	-2.7	-1.6
Ever highly irritable/argumentative for 2 days	2.9	3.5	3.7	-1.9	-1.8
Smoking Status	2.8	6.8	12.0	3.5	1.2
Length of working week for main job	2.7	3.0	3.4	-1.8	-1.6
Heart disease (mother)	2.7	3.3	4.9	1.3	2.2
Breast Cancer	2.6	6.4	8.4	2.1	2.9
Medication: Allopurinol	2.6	3.4	3.5	1.9	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	2.5	3.3	4.3	2.1	1.5
Forced expiratory volume in 1-second (FEV1), Best measure	2.5	8.1	11.5	-3.4	-2.2
Forced vital capacity (FVC)	2.4	9.2	9.4	-3.0	-3.1
Major Depression (MDD)	2.2	2.6	4.4	2.1	0.9
Frequency of tiredness / lethargy in last 2 weeks	2.2	3.5	3.8	2.0	1.8
Breast cancer (self-reported)	2.2	2.6	3.1	1.8	1.4
Wears glasses or contact lenses	2.2	2.6	2.9	-1.7	-1.5
Hearing aid user	2.2	2.5	3.6	1.9	1.1
Rheumatoid Arthritis	2.1	2.8	3.9	-1.3	-2.0
Illness, injury, bereavement, stress in last 2 years	2.1	2.6	3.6	1.3	1.9
Prostate Cancer	2.0	2.9	3.3	-1.6	-1.8
Medication: Lansoprazole	2.0	2.2	3.5	-1.0	-1.9
Standing height	2.0	19.4	20.0	-4.5	-4.3
Leg pain on walking	2.0	2.5	2.7	1.5	1.7
Number of self-reported non-cancer illnesses	2.0	3.5	3.5	1.9	1.9
Depression (Nagel 2018)	1.9	2.8	3.9	2.0	1.3
Chronotype (morning person)	1.9	4.3	5.6	-2.4	-1.8
Diabetes (father)	1.9	2.4	2.7	-1.6	-1.4
Diabetes (mother)	1.9	2.4	2.8	1.7	1.4
Multivitamins +/- minerals	1.9	2.4	2.7	-1.4	-1.6
Sitting height	1.9	13.4	17.7	-3.0	-4.2
Serious illness, injury or assault to yourself	1.8	2.2	2.4	-1.4	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.7	5.2	-2.3	-1.5
Vascular/heart problems diagnosed by doctor	1.8	4.9	5.0	-2.2	-2.2
Average weekly spirits intake	1.7	2.1	3.1	1.1	1.7
Medication: Metformin	1.7	2.4	3.8	1.9	1.0
Arm fat percentage (right)	1.7	6.6	8.5	2.9	2.2
Headache pain in last month	1.7	2.9	3.6	1.9	1.5
Eye problems/disorders: None of the above	1.7	1.9	2.7	1.7	1.1
Number of treatments/medications taken	1.6	2.8	3.4	1.5	1.8
Qualifications: A levels/AS levels or equivalent	1.6	3.5	4.7	2.2	1.5
Commuting to job workplace: Car/motor vehicle	1.6	1.9	2.6	1.1	1.6
Supplements: Vitamin C	1.6	1.9	2.4	-1.6	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	2.3	1.5	1.0
Miserableness	1.6	2.7	4.5	2.1	0.9
Frequency of depressed mood in last 2 weeks	1.5	2.1	3.6	1.9	0.8
Hand grip strength (right)	1.5	4.1	4.6	-2.1	-1.9
Exposure to tobacco smoke at home	1.5	1.6	2.4	0.9	1.6
Average weekly red wine intake	1.5	2.2	3.4	1.9	1.0
BMI	1.4	8.4	10.7	3.3	2.5
Forced expiratory volume in 1-second (FEV1)	1.4	4.8	6.3	-2.5	-1.8
Age at last live birth	1.4	2.0	3.2	0.9	1.8
Medication: Gliclazide	1.4	1.6	2.6	1.6	0.8
Alcohol drinker status: Never	1.4	1.7	2.1	1.1	1.5
Height	1.3	25.1	28.4	-5.3	-4.7
Hair/balding pattern: Pattern 3	1.3	2.0	2.9	-1.7	-1.1
Body fat percentage	1.3	5.0	6.5	2.5	1.9
Medication for cholesterol	1.3	2.0	3.3	-0.8	-1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	2.3	0.8	1.5
Average weekly beer plus cider intake	1.3	1.9	2.1	1.3	1.4
Alzheimer’s Disease (including proxy)	1.2	1.7	3.4	-0.1	-1.8
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	1.8	-1.4	-1.1
Trunk fat percentage	1.2	4.8	6.7	2.6	1.7
Body mass index (BMI)	1.2	5.0	6.4	2.5	1.9
Financial difficulties in last 2 years	1.2	1.6	2.2	1.5	1.0
Loud music exposure frequency	1.2	1.3	2.3	1.5	0.5
Qualifications: O levels/GCSEs or equivalent	1.2	2.0	2.2	1.5	1.3
Gout (self-reported)	1.2	1.6	1.8	1.3	1.2
Comparative height size at age 10	1.2	6.7	6.9	-2.6	-2.5
Arm fat percentage (left)	1.2	4.9	6.6	2.6	1.8
Heart disease (siblings)	1.2	1.4	2.0	1.0	1.4
Alzheimer’s Disease (in mother)	1.1	1.2	2.3	0.4	-1.5
Ovarian Cancer	1.1	1.4	1.6	1.3	1.1
Waist Hip Ratio (WHR)	1.1	4.9	7.7	1.5	2.8
Waist circumference	1.1	4.1	4.2	2.1	2.0
Leg fat percentage (right)	1.1	3.8	4.0	2.0	1.9
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	1.9	1.4	1.3
Leg fat percentage (left)	1.1	4.0	4.3	2.1	1.9
Schizophrenia vs Biploar Disorder	1.0	1.3	2.0	-1.4	-0.8
Hand grip strength (left)	1.0	2.7	4.0	-2.0	-1.2
Current tobacco smoking	1.0	1.6	3.0	0.3	-1.7
High blood pressure	1.0	2.9	4.0	2.0	1.4
Mouth/teeth dental problems	1.0	1.5	2.1	-1.4	-0.9
Medication: Ramipril	1.0	1.2	1.4	1.2	1.1
Trunk fat-free mass	1.0	5.8	6.4	-2.5	-2.3
Trunk predicted mass	1.0	6.0	6.5	-2.5	-2.3
Family relationship satisfaction	1.0	1.2	2.0	0.7	1.4
Loneliness, isolation	1.0	1.4	1.5	1.1	1.2
HbA1C	0.9	1.0	1.9	-1.4	0.3
Lung FEV1/FVC ratio	0.9	4.4	5.0	1.9	2.2
Vitamin and mineral supplements	0.9	1.2	1.2	1.1	1.1
Hayfever/allergic rhinitis (self-reported)	0.9	1.1	1.3	1.2	1.0
Illnesses of siblings	0.9	1.2	1.6	-0.9	-1.3
Hypertension (Self-reported)	0.9	2.5	3.2	1.8	1.4
Smoking status: Current	0.9	1.4	2.7	0.4	-1.7
Medication: Paracetamol	0.9	1.4	2.7	1.6	0.5
Crohns Disease (2017)	0.8	1.7	2.0	1.2	1.4
Neuroticism (2016)	0.8	1.1	1.3	1.2	0.9
Pain all over the body in last month	0.8	0.8	1.3	-1.1	-0.6
Father’s age at death	0.8	1.1	1.5	-1.2	-0.8
Pulse rate	0.8	1.3	1.7	-1.3	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	1.0	1.0	0.9
Overall health rating	0.8	1.6	2.7	1.6	0.7
Alzheimer’s Disease (in father)	0.7	0.8	1.3	-0.4	-1.2
Lung FVC	0.7	3.4	4.6	-2.1	-1.5
Medication: Co-codamol	0.7	0.8	1.5	0.2	1.2
Qualifications: None of the above	0.7	1.5	1.7	1.3	1.2
Mouth/teeth dental problems: Dentures	0.7	1.3	1.5	-1.0	-1.2
Tense / ‘highly strung’	0.7	1.1	1.9	-0.6	-1.4
Hair/balding pattern: Pattern 4	0.7	1.8	2.4	-1.5	-1.1
Birth weight	0.7	1.5	2.4	0.7	1.6
Mean time to correctly identify matches	0.7	1.3	2.4	0.5	1.6
Illnesses of siblings: Diabetes	0.7	0.8	1.1	0.7	1.1
Mood swings	0.7	1.3	2.6	0.2	-1.6
Ever had bowel cancer screening	0.7	0.8	1.0	1.0	0.8
Average weekly champagne plus white wine intake	0.7	1.0	1.2	0.9	1.1
Verbal and Numeric Reasoning (VNR)	0.6	1.4	2.1	0.8	-1.5
Primary Biliary Cirrhosis	0.6	0.9	1.7	1.3	0.1
Systolic Blood Pressure	0.6	2.9	5.7	-0.4	-2.4
Ever used hormone-replacement therapy (HRT)	0.6	0.8	0.9	-1.0	-0.8
Supplements: Glucosamine	0.6	0.7	1.4	-0.3	-1.2
Fluid intelligence score	0.6	1.2	2.3	1.5	-0.1
Worrier / anxious feelings	0.6	1.1	1.5	-0.8	-1.2
Arm fat mass (right)	0.6	2.6	3.5	1.9	1.3
Medication: Paracetamol	0.6	1.0	1.9	1.4	0.3
Number of full sisters	0.6	0.7	1.2	-0.4	-1.1
Knee pain experienced in last month	0.6	1.0	1.2	-0.9	-1.1
Back pain experienced in last month	0.6	0.9	1.3	1.1	0.7
Ever had prostate specific antigen (PSA) test	0.6	0.6	1.0	-1.0	-0.5
Diastolic blood pressure, automated reading	0.6	1.7	3.4	-0.1	-1.9
Age at First Birth	0.5	0.7	0.7	0.9	0.8
Medication: Atenolol	0.5	0.6	1.2	-1.1	-0.1
Nervous feelings	0.5	0.9	1.3	-1.2	-0.7
Falls in the last year	0.5	0.6	1.0	1.0	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.0	-0.5	-1.0
Lung cancer (father)	0.5	0.6	0.8	0.7	0.9
Health satisfaction	0.5	0.6	0.9	0.6	1.0
Medication for pain relief, constipation, heartburn	0.5	0.8	1.2	-1.1	-0.7
Whole body fat mass	0.5	2.0	2.9	1.7	1.1
Diabetes diagnosed by doctor	0.5	0.9	1.4	1.2	0.6
Qualifications: nursing, teaching	0.5	0.8	0.8	-0.9	-0.9
Osteoarthritis (self-reported)	0.5	0.7	1.0	1.0	0.6
Whole body water mass	0.5	2.8	3.0	-1.6	-1.7
Arm fat mass (left)	0.5	1.9	2.7	1.6	1.1
Financial situation satisfaction	0.5	0.6	1.2	-1.1	-0.0
Leg fat mass (left)	0.5	1.9	2.3	1.5	1.2
Depressed Affect (Nagel 2018)	0.4	0.8	1.5	1.2	-0.1
Intelligence (Savage-Jansen 2018)	0.4	1.3	1.5	1.0	-1.2
Mean Putamen Volume	0.4	0.4	0.8	0.9	0.1
Severe depression (siblings)	0.4	0.4	0.6	0.8	0.5
Age when periods started (menarche)	0.4	0.9	1.3	0.7	1.2
Trunk fat mass	0.4	1.8	2.7	1.6	0.9
Alcohol usually taken with meals	0.4	0.7	1.2	1.1	-0.4
Number of live births	0.4	0.6	1.1	1.0	0.4
Happiness	0.4	0.5	0.6	0.6	0.8
Breastfed as a baby	0.4	0.5	1.0	1.0	0.1
Birth weight of first child	0.4	0.8	1.4	0.4	1.2
Blood clot in the leg (DVT)	0.4	0.5	0.6	0.8	0.6
Arm fat-free mass (right)	0.4	1.9	2.0	-1.3	-1.4
Wheeze or whistling in the chest in last year	0.4	0.7	1.4	1.2	0.0
Qualifications: College or University degree	0.4	1.1	2.1	-1.5	-0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.4	0.9	-0.9	0.1
Migraine (self-reported)	0.4	0.5	1.0	-0.3	-1.0
Medication: Ibuprofen	0.4	0.5	1.0	0.1	-1.0
Leg fat mass (right)	0.4	1.7	2.0	1.4	1.1
Arm predicted mass (right)	0.4	1.9	2.2	-1.5	-1.3
Chest pain or discomfort	0.4	0.5	0.9	0.4	0.9
Whole body fat-free mass	0.4	2.4	2.6	-1.5	-1.6
Commuting to job workplace: Walk	0.4	0.5	0.9	0.1	-1.0
Illnesses of father: None of the above (group 1)	0.4	0.5	0.7	-0.8	-0.6
Guilty feelings	0.4	0.5	0.9	1.0	0.4
Tinnitus: Yes, now most or all of the time	0.4	0.5	0.8	0.4	0.9
Eye problems/disorders: Glaucoma	0.4	0.4	0.7	-0.3	0.8
Irritability	0.4	0.6	1.1	-0.4	-1.0
Risk taking	0.4	0.5	0.9	1.0	0.3
Fractured/broken bones in last 5 years	0.4	0.5	1.0	0.0	1.0
Supplements: Calcium	0.4	0.4	0.6	0.5	0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.9	0.2	1.0
Bipolar Disorder (2018)	0.3	0.4	0.9	-0.1	-0.9
Irritable Bowel Disease (IBD)	0.3	0.8	1.2	1.1	0.7
Body Mass Index (BMI) (2010)	0.3	0.4	0.5	0.6	0.7
Lupus	0.3	0.5	0.9	-0.9	0.2
Triglycerides	0.3	0.5	1.0	-1.0	0.2
Blood White Count	0.3	2.2	4.4	2.1	-0.1
Impedance of leg (right)	0.3	1.5	2.5	-1.6	-0.7
Townsend deprivation index at recruitment	0.3	0.4	0.8	0.9	0.2
Stomach or abdominal pain in last month	0.3	0.4	0.7	0.2	-0.8
High blood pressure (mother)	0.3	0.5	0.6	-0.8	-0.5
Impedance of leg (left)	0.3	1.3	2.1	-1.5	-0.6
Number of incorrect matches in round	0.3	0.5	0.7	-0.8	-0.5
Hearing difficulty/problems with background noise	0.3	0.4	0.6	-0.8	-0.5
Heart attack	0.3	0.4	0.9	0.0	0.9
Glaucoma (self-reported)	0.3	0.4	0.7	-0.1	0.9
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.0	-1.0	-0.5
Medication: Amlodipine	0.3	0.4	0.6	0.6	0.7
Pulse rate, automated reading	0.3	1.0	2.0	-0.0	-1.4
Suffer from ‘nerves’	0.3	0.5	0.7	0.5	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.8	0.2	-0.9
Illnesses of father: High blood pressure	0.3	0.3	0.7	0.0	0.8
Basal metabolic rate	0.3	1.6	2.0	-1.1	-1.4
Arm fat-free mass (left)	0.3	1.6	1.6	-1.3	-1.3
Arm predicted mass (left)	0.3	1.3	1.4	-1.1	-1.2
Ulcerative Colitis (UC)	0.2	0.4	0.7	0.9	0.2
Crohns Disease (2012)	0.2	0.3	0.6	-0.8	0.2
HDL Cholesterol	0.2	0.3	0.5	0.7	0.3
Blood Eosinophil Count	0.2	1.5	2.6	1.6	0.6
Allergy or Eczema	0.2	0.5	1.0	1.0	0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.6	0.8	-0.2
Neuroticism	0.2	0.4	0.4	0.6	-0.6
Sensitivity / hurt feelings	0.2	0.4	0.8	0.9	-0.2
Hearing difficulty/problems: Yes	0.2	0.3	0.6	0.0	-0.8
Relative age of first facial hair	0.2	0.4	0.8	-0.1	-0.9
Systolic blood pressure, automated reading	0.2	0.6	0.9	0.9	-0.6
Supplements: Zinc	0.2	0.2	0.4	-0.6	-0.2
Average weekly fortified wine intake	0.2	0.2	0.4	0.6	-0.3
Maternal smoking around birth	0.2	0.3	0.6	0.3	0.8
Fed-up feelings	0.2	0.4	0.8	-0.1	-0.9
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.0	-0.1	-1.0
Allergy	0.2	0.6	1.0	-0.3	1.0
Time employed in main current job	0.2	0.2	0.4	-0.6	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	-0.2	-0.7
Peak expiratory flow (PEF)	0.2	0.4	0.7	-0.8	-0.1
Pulse wave reflection index	0.2	0.2	0.3	0.4	0.6
Worry too long after embarrassment	0.2	0.3	0.6	-0.1	-0.8
Age at first live birth	0.2	0.4	0.7	-0.1	0.8
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.4	0.6	0.0
Ever depressed for a whole week	0.2	0.2	0.3	0.4	0.5
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.2	-0.4	-0.5
Neuroticism (Nagel 2018)	0.1	0.3	0.4	0.3	-0.7
Worry (Nagel 2018)	0.1	0.3	0.3	-0.5	-0.5
Reaction Time	0.1	0.3	0.5	-0.2	0.7
Schizophrenia (2014)	0.1	0.3	0.5	-0.0	-0.7
Blood Platelet Count	0.1	0.9	1.5	1.2	-0.6
Heel T-Score	0.1	0.6	0.8	0.6	-0.9
Hypothyroidism (self reported)	0.1	0.3	0.5	-0.7	-0.1
Respiratory disease	0.1	0.2	0.4	-0.2	-0.6
Tanning	0.1	0.8	1.3	-0.6	-1.2
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	-0.2	0.3
Leg fat-free mass (left)	0.1	0.7	1.2	-0.4	-1.1
Relative age voice broke	0.1	0.1	0.3	0.5	0.0
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.2	0.2	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.4	-0.1	-0.6
Qualifications: CSEs or equivalent	0.1	0.1	0.2	0.3	-0.4
Medication: Levothyroxine sodium	0.1	0.1	0.2	-0.5	-0.0
Chronic bronchitis/emphysema (father)	0.1	0.1	0.1	0.3	0.4
Leg predicted mass (left)	0.1	0.7	1.2	-0.4	-1.1
Had menopause	0.1	0.2	0.3	0.3	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.2	-0.2	-0.5
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.2	0.4	0.3
Diabetes (self-reported)	0.1	0.2	0.3	0.2	-0.5
Neuroticism score	0.1	0.3	0.5	0.4	-0.7
Hip circumference	0.1	0.4	0.5	0.7	-0.5
Alcohol intake versus 10 years previously	0.1	0.2	0.2	-0.5	-0.4
Depression (self-reported)	0.1	0.1	0.1	0.3	-0.3
Illnesses of mother	0.1	0.2	0.2	-0.4	-0.4
Impedance of arm (left)	0.1	0.4	0.8	-0.4	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.3	0.5	0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.1	-0.3	-0.2
Exposure to tobacco smoke outside home	0.1	0.1	0.3	0.0	-0.5
Number of children fathered	0.1	0.1	0.3	0.5	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	-0.1	0.5
Shortness of breath walking on level ground	0.1	0.1	0.1	0.2	0.3
Emphysema/chronic bronchitis	0.1	0.1	0.2	0.2	-0.4
Medication: Blood pressure	0.1	0.2	0.2	0.3	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.1	-0.4	-0.1
Leg fat-free mass (right)	0.1	0.7	1.3	-0.4	-1.1
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.3	-0.3	0.5
Long-standing illness, disability or infirmity	0.1	0.2	0.3	-0.0	0.6
Eye problems/disorders: Cataract	0.1	0.1	0.1	-0.4	-0.0
Mineral and other dietary supplements	0.1	0.1	0.3	-0.1	0.5
Asthma (self-reported)	0.1	0.3	0.5	-0.3	-0.7
Osteoporosis (self-reported)	0.1	0.1	0.1	0.3	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.5	-0.7	0.1
Leg predicted mass (right)	0.1	0.8	1.3	-0.5	-1.1
Mother’s age at death	0.1	0.1	0.1	-0.3	0.2
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.2	0.4	-0.4
Pain experienced in last month	0.1	0.2	0.3	-0.0	0.6
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.2	0.4	0.4
Alcohol drinker status: Previous	0.1	0.1	0.1	0.3	-0.2
Impedance of whole body	0.1	0.4	0.4	-0.6	-0.6
Bipolar Disorder or Schizophrenia	0.0	0.1	0.1	0.2	-0.4
Schizophrenia (2018)	0.0	0.1	0.2	0.4	0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.1	-0.1	-0.3
Ulcerative Colitis	0.0	0.1	0.1	0.4	0.0
Hair Pigment	0.0	0.3	0.4	-0.4	0.6
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	0.1	-0.1
Medication for hormone replacement therapy	0.0	0.1	0.1	-0.1	-0.3
Taking other prescription medications	0.0	0.0	0.1	0.2	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.0	0.0	0.2	0.1
Hair/balding pattern: Pattern 2	0.0	0.1	0.1	-0.0	-0.3
Weight	0.0	0.1	0.1	0.4	-0.1
Impedance of arm (right)	0.0	0.0	0.1	0.2	-0.2
Noisy workplace	0.0	0.1	0.1	0.3	0.0
Asthma	0.0	0.1	0.1	-0.1	-0.3
Prospective memory result	0.0	0.0	0.1	-0.2	0.2
Pulse wave Arterial Stiffness index	0.0	0.0	0.0	-0.2	0.0
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.1	0.2	-0.1
High blood pressure (siblings)	0.0	0.1	0.1	-0.3	-0.1
Comparative body size at age 10	0.0	0.1	0.1	0.2	0.3
Pulse wave peak to peak time	0.0	0.1	0.1	-0.1	-0.3
Neck or shoulder pain in last month	0.0	0.0	0.0	-0.2	-0.1
Medication: Omeprazole	0.0	0.0	0.0	-0.2	-0.0
Medication: Seretide 50 evohaler	0.0	0.0	0.1	-0.3	0.1
Alcohol intake frequency.	0.0	0.1	0.1	-0.2	0.3
Friendships satisfaction	0.0	0.0	0.1	0.2	0.2
Ever taken oral contraceptive pill	0.0	0.0	0.1	0.3	0.1
Commuting to job workplace: Public transport	0.0	0.0	0.0	0.2	0.1
Medication: Blood pressure	0.0	0.0	0.0	0.1	0.1
Medication: Bendroflumethiazide	0.0	0.1	0.1	-0.0	0.3
Medication: Lisinopril	0.0	0.0	0.1	0.0	-0.3
Age started oral contraceptive pill	0.0	0.1	0.1	0.2	0.3
Unable to work because of sickness or disability	0.0	0.1	0.1	0.2	0.3
Commuting to job workplace: Cycle	0.0	0.0	0.1	-0.0	-0.3
Basal cell carcinoma (self-reported)	0.0	0.0	0.1	-0.1	-0.3

Hub : Genes

ABCG5

Models

Trait associations