[Hub]/) : Traits : Blood Red Count : ← →

chr1:11,170,131-13,176,463

Best TWAS P=6e-13 · Best GWAS P=4.03e-13 conditioned to 0.0957

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells EBV-transformed lymphocytes	MTHFR	0.33	0.12	lasso	6	0.09	7.9e-04	5.4	5.4	5.6e-08	0.81	0.32	0.29	FALSE
2	GTEx	Cells Transformed fibroblasts	CLCN6	0.08	0.02	enet	17	0.05	1.6e-04	7.0	6.6	3.4e-11	0.75	0.01	0.98	FALSE
3	GTEx	Skin Not Sun Exposed Suprapubic	CLCN6	0.12	0.03	lasso	3	0.04	3.3e-03	5.7	6.9	3.9e-12	0.81	0.02	0.94	FALSE
4	GTEx	Skin Sun Exposed Lower leg	CLCN6	0.08	0.00	lasso	3	0.01	7.9e-02	2.6	5.6	1.8e-08	0.65	0.03	0.66	FALSE
5	GTEx	Spleen	CLCN6	0.21	0.10	lasso	3	0.06	1.3e-02	5.4	5.8	8.8e-09	0.87	0.04	0.70	FALSE
6	NTR	Blood	CLCN6	0.01	0.01	lasso	2	0.01	3.0e-04	5.2	5.3	1.1e-07	0.76	0.40	0.51	FALSE
7	YFS	Blood	DHRS3	0.02	0.02	lasso	3	0.01	3.5e-05	-5.9	5.6	2.2e-08	0.01	0.00	1.00	TRUE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	CLCN6	0.06	0.06	blup	104	0.06	5.0e-12	4.4	6.3	3.4e-10	0.74	0.33	0.67	FALSE
9	The Cancer Genome Atlas	Colon Adenocarcinoma	CLCN6	0.14	0.05	blup	104	0.09	1.2e-05	7.3	7.1	1.5e-12	0.81	0.01	0.98	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	MTHFR	0.07	0.01	blup	92	0.04	2.9e-03	3.7	5.3	1.1e-07	0.74	0.04	0.47	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CLCN6	0.04	0.06	lasso	2	0.05	1.1e-06	4.4	5.2	2.7e-07	0.69	0.09	0.90	FALSE
12	The Cancer Genome Atlas	Lung Adenocarcinoma	CLCN6	0.06	0.04	blup	104	0.04	5.2e-06	7.0	7.2	6.0e-13	0.90	0.01	0.99	TRUE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	CLCN6	0.10	0.07	blup	104	0.07	3.9e-08	4.3	5.4	7.5e-08	0.58	0.19	0.80	FALSE
14	The Cancer Genome Atlas	Stomach Adenocarcinoma	CLCN6	0.07	0.04	blup	104	0.05	2.4e-04	7.3	6.3	3.8e-10	0.93	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	CLCN6	0.08	0.02	blup	104	0.05	2.5e-05	4.8	7.1	1.3e-12	0.64	0.18	0.80	FALSE