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chr2:181,042,370-182,636,467

Best TWAS P=1.72e-22 · Best GWAS P=1.76e-21 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Nerve Tibial	UBE2E3	0.09	0.03	lasso	3	0.03	6.4e-03	-9.5	-9.8	1.7e-22	0.99	0.01	0.98	TRUE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UBE2E3	0.04	0.02	blup	61	0.02	1.4e-03	-9.5	-9.6	9.4e-22	0.89	0.01	0.90	FALSE
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UBE2E3	0.02	0.00	blup	61	0.01	1.1e-02	5.2	-9.3	1.5e-20	0.79	0.02	0.76	FALSE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	UBE2E3	0.05	0.03	blup	61	0.03	4.0e-04	-9.5	-9.3	1.5e-20	0.92	0.01	0.98	FALSE
4	GTEx	Esophagus Muscularis	UBE2E3	0.10	0.09	lasso	3	0.08	2.2e-05	-9.4	-9.2	5.4e-20	0.83	0.02	0.98	FALSE
1	GTEx	Artery Aorta	UBE2E3	0.09	0.00	lasso	3	0.01	1.6e-01	-9.5	-9.0	3.3e-19	0.89	0.03	0.78	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	UBE2E3	0.25	0.06	enet	39	0.12	2.5e-07	-7.1	-8.3	1.3e-16	0.64	0.03	0.97	FALSE
2	GTEx	Brain Hippocampus	FTH1P20	0.18	0.02	lasso	6	0.00	4.3e-01	-8.7	8.3	1.4e-16	-0.78	0.04	0.48	FALSE
8	NTR	Blood	UBE2E3	0.02	0.00	bslmm	446	0.00	1.1e-02	-9.4	-7.5	6.9e-14	0.62	0.02	0.93	FALSE
3	GTEx	Esophagus Mucosa	UBE2E3	0.07	0.02	enet	22	0.06	7.9e-05	3.9	-6.9	6.2e-12	0.52	0.14	0.77	FALSE
6	GTEx	Ovary	UBE2E3	0.25	0.09	lasso	8	0.10	1.5e-03	6.4	-6.8	1.0e-11	0.62	0.08	0.55	FALSE