Best TWAS P=2.09e-10 · Best GWAS P=4.2e-12 conditioned to 0.0259
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | COL5A2 | 0.14 | 0.13 | bslmm | 351 | 0.13 | 4.3e-15 | -6.2 | -5.8 | 7.4e-09 | 0.44 | 0.27 | 0.73 | FALSE |
| 2 | GTEx | Thyroid | SLC40A1 | 0.11 | 0.12 | lasso | 1 | 0.11 | 5.1e-09 | -6.2 | -6.2 | 5.3e-10 | 0.51 | 0.20 | 0.80 | FALSE |
| 3 | NTR | Blood | SLC40A1 | 0.01 | 0.01 | lasso | 3 | 0.01 | 6.2e-05 | -5.9 | -6.4 | 2.1e-10 | 0.68 | 0.13 | 0.80 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | SLC40A1 | 0.08 | 0.11 | lasso | 3 | 0.10 | 7.8e-13 | -5.4 | -5.7 | 1.2e-08 | 0.61 | 0.81 | 0.19 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | COL5A2 | 0.06 | 0.06 | lasso | 3 | 0.06 | 1.2e-07 | -6.2 | -6.1 | 1.1e-09 | 0.39 | 0.29 | 0.71 | TRUE |
| 6 | YFS | Blood | SLC40A1 | 0.21 | 0.10 | enet | 62 | 0.17 | 1.6e-52 | -5.4 | -5.8 | 5.5e-09 | 0.68 | 0.96 | 0.04 | FALSE |