TWAS
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Models
Genes
Traits
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Traits
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Blood Red Count
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chr2:207,244,783-208,729,540
Best TWAS P=3.66e-12 · Best GWAS P=4.66e-13 conditioned to 0.0332
207.2M
207.4M
207.6M
207.8M
208M
208.2M
208.4M
208.6M
208.8M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Thyroid
KLF7
0.18
0.15
lasso
3
0.13
3.2e-10
7
6.9
3.7e-12
0.92
0.01
0.99
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
KLF7
0.05
0.03
enet
13
0.02
2.3e-03
6
6.3
2.6e-10
0.80
0.02
0.73
FALSE