Best TWAS P=3.66e-12 · Best GWAS P=4.66e-13 conditioned to 0.0332
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | KLF7 | 0.18 | 0.15 | lasso | 3 | 0.13 | 3.2e-10 | 7 | 6.9 | 3.7e-12 | 0.92 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | KLF7 | 0.05 | 0.03 | enet | 13 | 0.02 | 2.3e-03 | 6 | 6.3 | 2.6e-10 | 0.80 | 0.02 | 0.73 | FALSE |