TWAS
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Models
Genes
Traits
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Traits
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Blood Red Count
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chr3:15,658,863-17,814,553
Best TWAS P=2.55e-11 · Best GWAS P=1.38e-42 conditioned to 7.68e-35
16M
16.5M
17M
17.5M
0
10
20
30
40
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
RFTN1
0.09
0.00
bslmm
640
0.01
1.4e-02
-1.40
6.7
2.5e-11
0.17
0.32
0.03
TRUE
2
METSIM
Adipose
PLCL2
0.08
0.03
lasso
6
0.04
2.3e-06
0.54
-5.2
2.6e-07
-0.09
1.00
0.00
TRUE