TWAS
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Usage
Models
Genes
Traits
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Traits
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Blood Red Count
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chr4:102,736,456-104,237,340
Best TWAS P=5.48e-12 · Best GWAS P=8.46e-25 conditioned to 8.11e-22
102.8M
103M
103.2M
103.4M
103.6M
103.8M
104M
104.2M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Testicular Germ Cell Tumors
NFKB1
0.10
0.06
blup
90
0.07
2.2e-03
-6.5
6.9
5.5e-12
0.11
0.23
0.27
TRUE
3
The Cancer Genome Atlas
Thyroid Carcinoma
NFKB1
0.06
0.09
enet
7
0.09
9.1e-09
-6.7
-6.7
2.5e-11
-0.11
0.44
0.56
FALSE
1
YFS
Blood
NFKB1
0.04
0.03
lasso
6
0.03
5.4e-09
-6.6
-6.6
4.6e-11
-0.13
1.00
0.00
FALSE