Best TWAS P=5.48e-12 · Best GWAS P=8.46e-25 conditioned to 8.11e-22
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | NFKB1 | 0.04 | 0.03 | lasso | 6 | 0.03 | 5.4e-09 | -6.6 | -6.6 | 4.6e-11 | -0.13 | 1.00 | 0.00 | FALSE |
| 2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | NFKB1 | 0.10 | 0.06 | blup | 90 | 0.07 | 2.2e-03 | -6.5 | 6.9 | 5.5e-12 | 0.11 | 0.23 | 0.27 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | NFKB1 | 0.06 | 0.09 | enet | 7 | 0.09 | 9.1e-09 | -6.7 | -6.7 | 2.5e-11 | -0.11 | 0.44 | 0.56 | FALSE |