Best TWAS P=4.01e-10 · Best GWAS P=1.15e-10 conditioned to 0.0257
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100506548 | 0.10 | 0.10 | lasso | 6 | 0.11 | 7.4e-13 | 5.2 | -5.2 | 1.7e-07 | -0.76 | 0.68 | 0.32 | FALSE |
| 2 | GTEx | Artery Tibial | TTC33 | 0.08 | 0.08 | lasso | 2 | 0.06 | 1.1e-05 | 5.6 | 5.6 | 2.8e-08 | 0.88 | 0.10 | 0.89 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | RPL37 | 0.04 | 0.06 | lasso | 1 | 0.06 | 1.1e-07 | 5.1 | 5.1 | 2.9e-07 | 0.67 | 0.19 | 0.81 | FALSE |
| 4 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | TTC33 | 0.05 | 0.04 | blup | 47 | 0.03 | 1.9e-02 | 4.7 | 5.7 | 1.1e-08 | 0.88 | 0.03 | 0.58 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PRKAA1 | 0.02 | 0.02 | blup | 51 | 0.01 | 1.9e-02 | 6.0 | -6.2 | 4.0e-10 | -0.83 | 0.01 | 0.94 | TRUE |