TWAS hub - PRKAA1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0154	0.0062	0.0013	0.008	0.008	0.010	0.008	0.011	0.0010	0.00081	0.00023	0.00075	0.00015
2	TCGA	Prostate Adenocarcinoma	0.0219	0.0119	0.0027	0.023	0.012	0.009	NA	0.009	0.0017	0.01900	0.03200	NA	0.03500

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Alzheimer’s Disease (in father)	8.9	9.7	10.0	3.1	3.2
Crohns Disease (2017)	8.2	17.9	35.4	-6.0	-0.7
Prostate Cancer	8.2	11.5	16.8	-4.1	-2.5
Crohns Disease (2012)	7.5	12.1	23.5	-4.8	-0.8
Medication: Ibuprofen (e.g. Nurofen)	6.2	7.9	13.3	-3.6	-1.6
Eye problems/disorders: None of the above	4.9	5.7	9.0	-3.0	-1.6
Medication: Ibuprofen	4.9	5.9	10.5	-3.2	-1.2
Medication for pain relief, constipation, heartburn	4.7	8.1	10.7	2.3	3.3
Irritable Bowel Disease (IBD)	4.0	9.5	15.9	-4.0	-1.8
Pain all over the body in last month	3.9	4.1	6.5	-1.4	-2.5
Medication: Paracetamol	3.8	6.4	7.0	-2.4	-2.6
Systolic blood pressure, automated reading	3.4	9.8	14.2	3.8	2.3
Pulse wave peak to peak time	3.4	4.0	5.1	-2.3	-1.7
Irritability	3.4	5.8	10.3	-3.2	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	3.3	3.8	5.3	1.5	2.3
Systolic Blood Pressure	3.2	15.8	25.7	5.1	2.4
Wears glasses or contact lenses	3.2	3.6	6.3	1.0	2.5
Hayfever/allergic rhinitis (self-reported)	3.1	4.1	6.0	-1.5	-2.5
Time employed in main current job	3.0	3.4	5.7	1.1	2.4
Age at First Birth	2.9	4.2	7.6	-0.9	-2.8
Medication: Ventolin 100micrograms inhaler	2.9	3.8	5.9	-2.4	-1.3
Pulse wave Arterial Stiffness index	2.8	3.3	4.5	2.1	1.4
Blood Red Count	2.7	25.7	39.1	-3.5	-6.2
Mood swings	2.7	4.9	5.5	-2.3	-2.1
Medication: Paracetamol	2.7	4.3	5.5	-1.7	-2.3
Diastolic blood pressure, automated reading	2.7	8.5	14.3	3.8	1.6
Mouth/teeth dental problems: Bleeding gums	2.6	3.4	6.2	-0.8	-2.5
Back pain experienced in last month	2.6	3.9	4.1	1.9	2.0
Average weekly beer plus cider intake	2.6	3.7	4.7	-2.2	-1.7
Number of live births	2.4	3.4	4.2	1.6	2.0
Average weekly red wine intake	2.3	3.3	5.4	2.3	1.1
Smoking status: Current	2.2	3.6	5.7	-1.2	-2.4
Bipolar Disorder (2011)	2.1	2.0	2.2	1.5	1.4
Mean Putamen Volume	2.1	2.4	3.4	1.1	1.8
Current tobacco smoking	2.1	3.4	6.2	-0.8	-2.5
Supplements: Glucosamine	2.1	2.8	3.9	1.3	2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	2.1	2.7	5.1	-2.3	-0.5
Medication: Seretide 50 evohaler	2.1	2.4	4.0	0.9	2.0
Average weekly champagne plus white wine intake	2.1	2.9	3.2	1.6	1.8
Bipolar Disorder or Schizophrenia	1.9	4.6	5.3	2.0	2.3
Rheumatoid Arthritis	1.9	2.6	4.1	-2.0	1.1
Wheeze or whistling in the chest in last year	1.9	3.3	4.0	-2.0	-1.6
Miserableness	1.9	3.3	5.4	-2.3	-1.1
Financial situation satisfaction	1.9	2.4	4.5	0.6	2.1
Allergy or Eczema	1.8	4.7	9.5	-3.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.0	5.1	-1.7	-2.3
Falls in the last year	1.8	2.4	3.9	2.0	1.0
Number of full brothers	1.8	2.2	3.1	1.8	1.2
Mineral and other dietary supplements	1.8	2.5	4.0	-1.0	-2.0
Illnesses of father: None of the above (group 1)	1.8	2.3	2.9	-1.7	-1.3
Lupus	1.7	2.6	3.6	1.3	1.9
Schizophrenia (2014)	1.7	3.7	4.0	1.9	2.0
Breastfed as a baby	1.7	2.1	2.7	1.2	1.7
Supplements: Vitamin C	1.7	2.0	2.8	1.7	1.1
Bipolar Disorder (2018)	1.6	2.6	2.8	1.7	1.5
Fasting Glucose	1.6	1.9	3.2	-0.7	-1.8
Exposure to tobacco smoke at home	1.6	1.8	2.3	-1.2	-1.5
Family relationship satisfaction	1.6	1.9	2.0	1.4	1.4
Mother’s age at death	1.6	2.0	3.4	-0.7	-1.9
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	3.2	-0.5	-1.8
Diabetes (self-reported)	1.5	2.3	2.8	-1.4	-1.7
Medication: Simvastatin	1.5	2.2	2.5	-1.6	-1.4
Illnesses of father: Heart disease	1.5	2.1	3.2	-1.0	-1.8
Hearing aid user	1.5	1.7	2.9	1.7	0.7
Medication: Bendroflumethiazide	1.5	2.2	4.4	2.1	0.2
Alzheimer’s Disease (including proxy)	1.4	2.1	3.3	1.8	0.9
Father’s age at death	1.4	1.9	2.0	-1.4	-1.3
Neck or shoulder pain in last month	1.4	2.0	3.3	-1.8	-0.9
Suffer from ‘nerves’	1.4	2.2	4.4	-0.3	-2.1
Eye problems/disorders: Cataract	1.4	1.6	2.5	1.6	0.9
Depressed Affect (Nagel 2018)	1.3	2.7	2.9	-1.6	-1.7
Depression (Nagel 2018)	1.3	1.9	2.6	-1.1	-1.6
HbA1C	1.3	1.4	1.8	1.0	1.3
Ever had hysterectomy (womb removed)	1.3	1.4	2.2	-0.8	-1.5
Hayfever, allergic rhinitis or eczema	1.3	2.7	5.3	-2.3	-0.4
Pulse rate	1.3	2.3	3.4	1.8	1.1
Ulcerative Colitis	1.2	1.7	2.8	-0.7	-1.7
Hair/balding pattern: Pattern 2	1.2	1.5	1.9	-1.4	-1.1
Impedance of arm (right)	1.2	5.4	9.2	-3.0	-1.3
Tense / ‘highly strung’	1.2	2.0	2.8	-1.1	-1.7
Diabetes diagnosed by doctor	1.2	2.0	2.3	-1.3	-1.5
Medication: Aspirin	1.2	1.6	2.8	0.5	-1.7
Schizophrenia (2018)	1.1	2.2	3.0	1.2	1.7
Type 2 Diabetes (T2D) (2012)	1.1	1.3	1.6	-1.0	1.2
Supplements: Zinc	1.1	1.2	2.1	0.6	1.4
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	2.7	0.1	-1.6
Illnesses of siblings	1.1	1.6	1.9	-1.1	-1.4
Number of children fathered	1.1	1.2	1.9	0.8	1.4
Age at first live birth	1.1	2.0	3.3	-1.8	-0.9
Medication: Aspirin	1.1	1.5	2.8	0.3	-1.7
Commuting to job workplace: Walk	1.1	1.2	1.9	-0.7	-1.4
Myopia	1.1	1.6	3.1	-1.7	0.2
Cardiovascular Disease	1.0	3.2	5.3	2.3	1.1
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	1.8	0.7	-1.3
Vitamin and mineral supplements	1.0	1.3	1.4	-1.1	-1.2
Severe depression (siblings)	1.0	1.1	2.1	0.4	1.5
Stomach or abdominal pain in last month	1.0	1.2	2.3	1.5	-0.3
Alcohol usually taken with meals	1.0	1.6	2.8	-0.7	1.7
Loud music exposure frequency	1.0	1.1	1.7	-1.3	-0.6
Impedance of whole body	1.0	5.0	9.0	-3.0	-1.0
Neuroticism (Nagel 2018)	0.9	2.1	2.3	-1.5	-1.4
Body Mass Index (BMI) (2010)	0.9	1.3	2.1	1.4	0.7
Blood Eosinophil Count	0.9	6.9	9.9	2.0	3.1
Blood White Count	0.9	6.8	9.5	-2.0	-3.1
Frequency of depressed mood in last 2 weeks	0.9	1.2	1.5	-1.2	-1.0
Serious illness, injury or assault to yourself	0.9	1.1	2.0	0.4	-1.4
Multivitamins +/- minerals	0.9	1.2	2.1	1.4	0.6
Financial difficulties in last 2 years	0.9	1.3	2.5	1.6	-0.2
Impedance of arm (left)	0.9	4.1	7.7	-2.8	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	1.3	-1.1	-1.1
Had major operations	0.9	1.1	1.6	1.3	0.7
Supplements: Fish oil (including cod liver oil)	0.9	1.2	1.5	1.2	1.0
Alcohol drinker status: Previous	0.9	1.1	1.9	-1.4	0.5
HDL Cholesterol	0.8	1.3	2.5	0.2	-1.6
Impedance of leg (right)	0.8	3.9	6.3	-2.5	-1.2
High blood pressure	0.8	2.2	3.4	1.9	1.0
High blood pressure (mother)	0.8	1.2	1.9	0.7	1.4
Impedance of leg (left)	0.8	3.9	5.8	-2.4	-1.4
Neuroticism score	0.8	1.7	2.6	-1.6	-0.8
Prospective memory result	0.8	0.9	0.9	0.9	1.0
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	1.8	-0.9	1.3
Birth weight	0.8	1.7	2.0	1.2	1.4
Emphysema/chronic bronchitis	0.8	0.9	1.7	-1.3	-0.2
Handedness (chirality/laterality): Left-handed	0.8	0.9	1.6	0.5	-1.3
Commuting to job workplace: Cycle	0.8	0.9	1.8	0.3	-1.3
Major Depression (MDD)	0.7	0.8	1.3	1.1	0.6
Breast Cancer	0.7	1.7	2.7	-1.6	-0.9
Ovarian Cancer	0.7	0.9	1.6	-1.3	0.5
Coronary Artery Disease (CAD)	0.7	0.8	1.7	-0.0	1.3
Type 2 Diabetes (T2D) (2018)	0.7	1.3	1.8	-1.0	-1.3
Lung FVC	0.7	3.5	5.0	1.4	2.2
Neuroticism	0.7	1.7	2.3	-1.5	-1.0
Sensitivity / hurt feelings	0.7	1.3	2.4	-0.4	1.6
Average weekly fortified wine intake	0.7	0.8	1.6	-0.0	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	1.1	-1.0	-1.0
Mouth/teeth dental problems	0.7	1.0	1.3	-0.9	1.1
Allergy	0.7	1.6	3.2	1.8	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.1	1.4	0.3
Noisy workplace	0.7	0.8	1.2	-1.1	-0.7
Medication: Cholesterol lowering	0.7	1.1	1.2	-1.0	-1.1
Headache pain in last month	0.7	1.1	1.4	-0.9	-1.2
High blood pressure (siblings)	0.7	1.0	1.8	1.4	0.5
Body fat percentage	0.7	2.9	4.9	-0.9	-2.2
Leg fat percentage (right)	0.7	2.5	4.7	-0.6	-2.2
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	1.2	-0.8	-1.1
Hypertension (Self-reported)	0.7	2.0	3.3	1.8	0.8
Loneliness, isolation	0.7	0.9	1.7	-0.3	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	1.0	-0.8	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	1.7	1.1	1.3
Number of self-reported non-cancer illnesses	0.7	1.1	2.1	0.5	1.4
Leg fat percentage (left)	0.7	2.6	5.0	-0.6	-2.2
Age started oral contraceptive pill	0.7	0.9	1.2	1.1	0.8
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.7	-0.2	-1.3
Worry (Nagel 2018)	0.6	1.3	1.6	-1.0	-1.2
Ulcerative Colitis (UC)	0.6	1.1	2.0	-0.4	-1.4
Hypothyroidism (self reported)	0.6	1.4	2.7	0.2	-1.7
Hearing difficulty/problems: Yes	0.6	0.9	1.1	1.0	0.8
Diabetes (father)	0.6	0.8	1.5	1.2	0.3
Diabetes (mother)	0.6	0.8	1.5	-1.2	-0.4
Trunk fat percentage	0.6	2.4	3.9	-0.9	-2.0
Alcohol intake versus 10 years previously	0.6	0.9	1.3	-1.2	-0.6
Worrier / anxious feelings	0.6	1.1	2.1	-1.5	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	2.0	1.2	1.4
Blood clot in the leg (DVT)	0.6	0.8	1.7	0.0	-1.3
Forced vital capacity (FVC), Best measure	0.6	2.1	2.7	1.3	1.6
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.4	-0.0	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.3	0.1	1.1
Osteoporosis (self-reported)	0.6	0.7	1.4	1.2	0.2
Medication: Blood pressure	0.6	1.2	1.7	1.3	0.8
Arm predicted mass (left)	0.6	2.9	5.9	2.4	0.1
Alzheimer’s Disease (in mother)	0.5	0.5	0.8	-0.5	-0.9
Medication: Atenolol	0.5	0.6	0.8	-0.9	-0.6
Forced vital capacity (FVC)	0.5	2.1	3.4	0.8	1.8
Arm fat percentage (right)	0.5	1.8	3.3	-0.6	-1.8
Happiness	0.5	0.6	0.7	-0.7	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.1	-1.0	0.3
Birth weight of first child	0.5	1.0	1.1	-0.9	-1.0
Worry too long after embarrassment	0.5	0.8	1.2	0.7	1.1
Shortness of breath walking on level ground	0.5	0.6	0.6	0.7	-0.8
Medication: Allopurinol	0.5	0.7	1.4	-1.2	-0.2
Medication: Omeprazole	0.5	0.6	1.0	1.0	-0.5
Arm predicted mass (right)	0.5	2.5	4.8	2.2	0.4
Leg pain on walking	0.5	0.7	0.9	0.7	-1.0
Ever had bowel cancer screening	0.5	0.6	1.2	-1.1	0.2
Medication: Gliclazide	0.5	0.5	0.7	-0.9	-0.6
Eye problems/disorders: Glaucoma	0.5	0.6	1.2	1.1	0.2
Alcohol drinker status: Never	0.5	0.6	1.2	-1.1	-0.2
Ever smoked	0.5	0.9	1.0	-0.9	-1.0
Risk taking	0.5	0.8	0.8	-0.8	-0.9
Schizophrenia vs Biploar Disorder	0.4	0.5	0.8	-0.9	-0.5
Triglycerides	0.4	0.6	1.2	0.2	1.1
Lung FEV1/FVC ratio	0.4	1.9	2.6	-1.1	-1.6
Medication: Metformin	0.4	0.5	0.5	-0.7	-0.7
Chronic bronchitis/emphysema (father)	0.4	0.5	0.7	0.6	0.9
Trunk fat mass	0.4	1.6	3.0	-0.4	-1.7
Past tobacco smoking	0.4	0.7	0.7	0.8	0.8
Had menopause	0.4	0.6	0.9	0.5	1.0
Medication: Lansoprazole	0.4	0.5	0.6	0.8	-0.6
Trunk predicted mass	0.4	2.0	3.8	2.0	0.5
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	1.2	-0.5	-1.1
Medication: Amlodipine	0.4	0.5	0.8	-0.5	0.9
Chronic bronchitis/emphysema (mother)	0.4	0.5	0.6	0.6	-0.8
Arm fat-free mass (right)	0.4	2.1	4.2	2.0	0.1
Exposure to tobacco smoke outside home	0.4	0.5	1.0	-0.1	-1.0
Medication: Blood pressure	0.4	0.8	1.4	1.2	-0.3
Alcohol intake frequency.	0.4	0.9	1.7	-1.3	0.2
Knee pain experienced in last month	0.4	0.7	0.8	-0.9	0.8
Whole body fat-free mass	0.4	2.2	4.2	2.1	0.5
Leg fat-free mass (right)	0.4	2.1	3.8	1.9	0.7
Arm fat percentage (left)	0.4	1.7	3.1	-0.5	-1.8
Whole body water mass	0.4	2.3	4.4	2.1	0.5
Leg predicted mass (right)	0.4	2.3	4.0	2.0	0.8
Guilty feelings	0.4	0.6	0.8	-0.9	0.6
High cholesterol (Self-reported)	0.4	0.7	1.1	-1.1	0.4
Medication: Lisinopril	0.4	0.6	0.8	0.6	0.9
Arm fat-free mass (left)	0.4	1.9	3.9	2.0	-0.0
Number of operations (self-reported)	0.4	0.6	0.8	0.7	0.9
Verbal and Numeric Reasoning (VNR)	0.3	0.7	0.8	0.8	0.9
Neuroticism (2016)	0.3	0.4	0.8	-0.2	-0.9
Number of treatments/medications taken	0.3	0.5	0.9	-0.2	-1.0
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.6	0.8	-0.4
Leg fat-free mass (left)	0.3	1.5	2.8	1.7	0.5
Townsend deprivation index at recruitment	0.3	0.4	0.6	0.6	0.8
Age when periods started (menarche)	0.3	0.8	1.3	0.6	1.1
Qualifications: CSEs or equivalent	0.3	0.4	0.5	-0.5	-0.7
Leg predicted mass (left)	0.3	1.5	2.9	1.7	0.5
Waist circumference	0.3	1.1	2.1	0.3	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.3	-1.1	-0.4
Trunk fat-free mass	0.3	1.9	3.6	1.9	0.5
Whole body fat mass	0.3	1.1	2.1	-0.2	-1.5
Leg fat mass (right)	0.3	1.2	2.4	0.1	-1.5
Chest pain or discomfort	0.3	0.4	0.7	-0.9	-0.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.6	0.5	0.8
Long-standing illness, disability or infirmity	0.3	0.4	0.8	0.9	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.6	-0.8	0.1
Qualifications: nursing, teaching	0.3	0.4	0.7	0.4	0.8
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.8	-0.4	-0.9
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.6	-0.1	-0.8
Commuting to job workplace: Public transport	0.3	0.4	0.7	0.3	0.9
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.5	-0.4	-0.7
Basal metabolic rate	0.3	1.4	2.8	1.7	0.1
Vascular/heart problems diagnosed by doctor	0.3	0.9	1.6	-1.3	-0.5
Leg fat mass (left)	0.3	1.1	2.2	0.1	-1.5
Intelligence (Savage-Jansen 2018)	0.2	0.5	0.9	-0.0	1.0
BMI	0.2	1.3	2.6	-0.0	-1.6
Smoking Status	0.2	0.4	0.7	-0.3	-0.8
Hand grip strength (left)	0.2	0.6	1.1	1.0	0.2
Angina	0.2	0.3	0.3	-0.5	-0.6
Medication for hormone replacement therapy	0.2	0.3	0.5	-0.7	0.2
Maternal smoking around birth	0.2	0.3	0.5	-0.7	-0.4
Relative age voice broke	0.2	0.4	0.7	-0.9	-0.0
Taking other prescription medications	0.2	0.3	0.7	0.8	0.1
Medication: Levothyroxine sodium	0.2	0.3	0.6	-0.8	0.1
Body mass index (BMI)	0.2	1.0	1.6	0.6	-1.3
Had other major operations	0.2	0.3	0.4	0.4	0.6
Heart attack	0.2	0.3	0.5	-0.4	-0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.3	0.3	1.1
Mouth/teeth dental problems: Dentures	0.2	0.3	0.5	0.7	-0.3
Asthma	0.2	0.5	0.7	-0.5	0.8
Lung cancer (father)	0.2	0.3	0.4	-0.7	-0.4
Arm fat mass (right)	0.2	0.9	1.7	0.2	-1.3
Length of working week for main job	0.2	0.2	0.3	-0.5	0.3
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.5	0.7	0.2
Health satisfaction	0.2	0.2	0.4	0.6	0.3
Qualifications: College or University degree	0.2	0.6	0.7	-0.8	-0.7
Asthma (self-reported)	0.2	0.5	0.9	-0.4	0.9
Osteoarthritis (self-reported)	0.2	0.3	0.3	-0.5	-0.5
Arm fat mass (left)	0.2	1.0	1.7	0.4	-1.3
Illnesses of father: High blood pressure	0.2	0.2	0.4	0.2	0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.4	-0.2	0.7
Basal cell carcinoma (self-reported)	0.2	0.2	0.4	-0.6	-0.3
Heart disease (siblings)	0.2	0.2	0.3	0.2	0.6
Reaction Time	0.1	0.2	0.4	-0.0	-0.6
LDL Cholesterol	0.1	0.2	0.4	0.7	0.2
Blood Platelet Count	0.1	1.7	3.3	-0.3	-1.8
Heel T-Score	0.1	0.6	0.9	0.9	0.5
Height	0.1	1.3	2.6	0.3	1.6
Respiratory disease	0.1	0.3	0.5	-0.1	0.7
Chronotype (morning person)	0.1	0.2	0.3	-0.6	0.1
Hair Pigment	0.1	1.5	2.1	-0.9	-1.5
Average weekly spirits intake	0.1	0.1	0.2	0.1	-0.5
Relative age of first facial hair	0.1	0.3	0.4	0.3	0.7
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.2	0.5	0.1
Medication: Co-codamol	0.1	0.1	0.1	0.3	-0.3
Pack years adult smoking proportion	0.1	0.1	0.2	0.4	-0.0
Hand grip strength (right)	0.1	0.3	0.5	0.7	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	0.5	-0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.1	-0.3	-0.4
Hearing difficulty/problems with background noise	0.1	0.2	0.3	0.5	-0.4
Qualifications: None of the above	0.1	0.3	0.4	-0.3	-0.7
Weight	0.1	0.6	0.8	0.7	-0.9
Hip circumference	0.1	0.3	0.5	0.1	-0.7
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	0.4	0.3
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.3	0.3	0.6
Depression (self-reported)	0.1	0.1	0.2	0.5	-0.1
Illnesses of mother	0.1	0.1	0.2	-0.5	0.2
Standing height	0.1	0.6	0.8	0.5	0.9
Hair/balding pattern: Pattern 4	0.1	0.2	0.3	0.5	0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.1	0.3	0.3
Gout (self-reported)	0.1	0.2	0.3	-0.6	0.1
Comparative body size at age 10	0.1	0.3	0.3	-0.6	0.5
Heart disease (mother)	0.1	0.1	0.2	-0.2	0.5
Comparative height size at age 10	0.1	0.4	0.4	0.7	0.6
Number of full sisters	0.1	0.2	0.2	-0.5	-0.4
Overall health rating	0.1	0.1	0.1	0.4	0.3
Age at last live birth	0.1	0.1	0.2	-0.4	-0.0
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.1	-0.3	-0.3
Smoking status: Previous	0.1	0.1	0.2	0.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.5	0.2	0.7
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.5	-0.2
Medication: Atorvastatin	0.1	0.1	0.3	-0.5	0.2
Fractured/broken bones in last 5 years	0.1	0.2	0.2	0.4	-0.4
Cholesterol lowering medication	0.1	0.1	0.2	0.2	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.2	0.4	-0.3
Pain experienced in last month	0.1	0.1	0.2	-0.2	-0.5
Supplements: Calcium	0.1	0.1	0.2	-0.4	0.2
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.3	-0.0	-0.6
Pack years of smoking	0.1	0.1	0.2	0.5	0.2
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.2	-0.1
Waist Hip Ratio (WHR)	0.0	0.2	0.2	0.5	-0.3
Tanning	0.0	0.3	0.4	0.6	-0.4
Fed-up feelings	0.0	0.0	0.1	-0.2	-0.1
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.0	0.0	-0.1
Sitting height	0.0	0.1	0.2	0.1	-0.4
Number of incorrect matches in round	0.0	0.0	0.0	-0.0	-0.2
Nervous feelings	0.0	0.0	0.0	0.2	0.0
Medication: Ramipril	0.0	0.0	0.0	-0.1	-0.0
Fluid intelligence score	0.0	0.1	0.1	-0.4	-0.1
Peak expiratory flow (PEF)	0.0	0.0	0.0	-0.1	0.1
Pulse wave reflection index	0.0	0.0	0.1	-0.3	-0.0
Glaucoma (self-reported)	0.0	0.0	0.1	0.3	0.0
Angina (self-reported)	0.0	0.1	0.1	-0.4	-0.0
Migraine (self-reported)	0.0	0.1	0.1	-0.3	-0.1
Mean time to correctly identify matches	0.0	0.1	0.1	-0.2	0.3
Pulse rate, automated reading	0.0	0.1	0.3	0.0	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.1	0.1	0.2	-0.3
Illnesses of siblings: Diabetes	0.0	0.1	0.1	-0.3	0.1
Friendships satisfaction	0.0	0.0	0.0	-0.1	-0.0
Medication for cholesterol	0.0	0.0	0.1	0.3	0.1
Breast cancer (self-reported)	0.0	0.0	0.0	0.1	0.1
Ever depressed for a whole week	0.0	0.1	0.1	0.3	0.2
Unable to work because of sickness or disability	0.0	0.0	0.0	-0.0	0.1

Hub : Genes

PRKAA1

Models

Trait associations