Best TWAS P=9.2e-09 · Best GWAS P=2.51e-09 conditioned to 0.0901
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Nucleus accumbens basal ganglia | PFDN1 | 0.16 | 0.01 | lasso | 5 | 0.03 | 5.6e-02 | 4.8 | 5.2 | 2.0e-07 | -0.81 | 0.04 | 0.59 | FALSE |
| 2 | YFS | Blood | HBEGF | 0.02 | 0.02 | lasso | 3 | 0.02 | 9.8e-07 | 4.8 | 5.3 | 1.4e-07 | -0.82 | 0.08 | 0.92 | FALSE |
| 3 | YFS | Blood | PFDN1 | 0.03 | 0.03 | lasso | 13 | 0.03 | 1.4e-10 | 4.7 | 5.5 | 5.0e-08 | -0.66 | 0.61 | 0.39 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | PFDN1 | 0.03 | 0.02 | blup | 47 | 0.02 | 5.5e-03 | -5.7 | 5.7 | 9.2e-09 | -0.93 | 0.01 | 0.90 | TRUE |