TWAS hub - HBEGF

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0216	0.0101	0.0020	0.021	0.006	0.018	0.009	0.018	1.9e-07	3.0e-03	1.3e-06	5e-04	9.8e-07
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0992	0.0475	0.0010	0.011	0.041	0.045	NA	0.031	1.9e-02	2.1e-05	7.0e-06	NA	1.7e-04
3	TCGA	Prostate Adenocarcinoma	0.0272	0.0147	0.0011	0.034	0.021	0.015	NA	0.022	1.7e-04	2.3e-03	8.6e-03	NA	2.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Mean time to correctly identify matches	10.4	19.8	34.9	5.9	-2.2	4.4
Verbal and Numeric Reasoning (VNR)	9.1	21.9	37.5	5.3	-0.5	6.1
Reaction Time	8.6	16.4	27.8	5.3	-2.4	4.0
Intelligence (Savage-Jansen 2018)	8.3	25.5	46.2	5.4	-0.7	6.8
Alzheimer’s Disease (including proxy)	8.0	11.6	18.4	-3.6	1.8	-4.3
Taking other prescription medications	6.6	10.2	14.4	3.8	-1.8	3.6
Wheeze or whistling in the chest in last year	6.5	11.5	18.0	3.3	-2.4	4.2
Worry too long after embarrassment	6.3	10.6	20.2	3.4	0.1	4.5
Birth weight of first child	5.4	9.8	17.8	-4.2	2.4	-2.4
Respiratory disease	5.2	11.7	25.3	2.0	-2.4	5.0
Fluid intelligence score	4.7	9.8	16.5	4.1	0.1	3.6
BMI	4.6	26.8	42.2	5.5	-2.9	6.5
Qualifications: CSEs or equivalent	4.5	5.9	8.3	-2.9	2.1	-2.3
Number of self-reported non-cancer illnesses	4.5	7.8	9.9	3.1	-2.1	3.1
Ever depressed for a whole week	4.5	5.6	10.3	3.2	-0.9	2.4
Qualifications: College or University degree	4.4	13.9	24.4	4.0	-1.1	4.9
Alzheimer’s Disease (in father)	4.3	4.7	9.3	-3.0	0.7	-2.1
Guilty feelings	4.3	6.4	12.3	2.7	-0.1	3.5
Impedance of whole body	4.3	22.1	36.9	-5.0	2.1	-6.1
Long-standing illness, disability or infirmity	4.2	6.4	9.7	2.5	-1.8	3.1
Ever unenthusiastic/disinterested for a whole week	4.0	4.9	7.6	2.8	-1.3	2.3
Family relationship satisfaction	4.0	4.9	10.6	3.3	-0.7	1.9
Mouth/teeth dental problems: Loose teeth	3.9	4.7	11.6	-0.4	3.4	-1.5
Shortness of breath walking on level ground	3.8	4.5	7.1	2.1	-1.5	2.7
Medication: Paracetamol	3.7	5.7	9.6	-2.0	1.8	-3.1
Risk taking	3.7	5.4	9.4	3.1	-1.6	2.1
Impedance of arm (left)	3.6	16.6	24.7	-4.2	2.8	-5.0
Peak expiratory flow (PEF)	3.6	8.4	13.0	-3.6	1.4	-3.2
Neuroticism	3.5	8.5	20.1	2.3	0.1	4.5
Past tobacco smoking	3.5	6.4	8.8	-2.4	2.2	-3.0
Impedance of arm (right)	3.5	16.1	25.3	-4.0	2.6	-5.0
Time employed in main current job	3.5	4.1	7.7	1.7	-1.3	2.8
Medication: Seretide 50 evohaler	3.5	4.1	8.8	1.8	-0.1	3.0
Irritability	3.5	5.9	10.9	2.4	-1.0	3.3
Chronotype (morning person)	3.4	7.8	16.7	-4.1	0.9	-2.5
Friendships satisfaction	3.4	4.2	9.8	3.1	0.4	1.6
Neuroticism (Nagel 2018)	3.3	7.8	15.4	2.4	-1.5	3.9
Body mass index (BMI)	3.3	14.0	21.4	4.0	-2.2	4.6
Mouth/teeth dental problems: Bleeding gums	3.3	4.3	6.3	-2.2	2.5	-1.4
Medication: Paracetamol	3.3	5.4	9.1	-2.4	1.1	-3.0
Financial situation satisfaction	3.2	4.0	7.5	2.7	-1.2	1.8
Bipolar Disorder (2011)	3.0	2.9	6.3	-1.3	-0.9	-2.5
Noisy workplace	3.0	3.7	4.8	-1.6	2.2	-1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	3.0	3.9	6.0	2.4	0.3	2.4
Neuroticism score	2.9	6.1	14.3	1.8	0.9	3.8
Smoking status: Previous	2.9	4.4	6.0	1.5	-2.2	2.5
Arm fat mass (right)	2.8	11.5	17.3	3.4	-2.4	4.2
Length of working week for main job	2.7	2.9	5.8	2.4	-0.2	1.7
Qualifications: NVQ or HND or HNC or equivalent	2.7	3.3	7.5	-0.6	1.4	-2.7
Impedance of leg (left)	2.6	12.5	20.8	-4.0	0.9	-4.6
Qualifications: None of the above	2.6	5.6	8.0	-2.8	-1.1	-2.8
Heart attack	2.6	3.3	8.9	3.0	-0.7	0.7
Hip circumference	2.6	11.4	15.4	2.9	-3.2	3.9
Eye problems/disorders: Glaucoma	2.6	3.1	7.4	1.2	-2.7	0.8
Medication: Metformin	2.5	3.5	5.6	2.4	0.0	2.2
Impedance of leg (right)	2.5	12.2	19.4	-4.0	1.0	-4.4
Asthma (self-reported)	2.5	5.0	12.7	0.5	-1.5	3.6
Arm fat mass (left)	2.5	10.4	15.3	3.2	-2.3	3.9
Tinnitus: Yes, now most or all of the time	2.4	2.8	5.5	-1.4	-2.3	-1.1
Primary Biliary Cirrhosis	2.3	3.3	5.8	-2.0	2.4	-0.6
Asthma	2.3	4.6	12.4	0.6	-1.0	3.5
Loneliness, isolation	2.3	3.2	5.5	2.4	0.3	2.0
Ever smoked	2.3	4.1	6.2	2.1	-1.3	2.5
Ever taken oral contraceptive pill	2.2	2.5	7.1	0.1	2.7	0.6
LDL Cholesterol	2.1	3.4	5.7	2.0	-0.5	2.4
Heart attack/myocardial infarction (self-reported)	2.1	2.7	7.7	2.8	-0.4	0.6
Waist Hip Ratio (WHR)	2.0	9.2	12.0	-3.5	3.0	-2.6
Number of treatments/medications taken	2.0	3.6	4.8	2.2	-2.0	1.4
Multivitamins +/- minerals	2.0	2.5	5.4	-2.3	1.3	-0.6
Weight	2.0	10.0	14.4	2.8	-2.8	3.8
Trunk fat-free mass	2.0	11.5	15.4	2.6	-3.5	3.9
Trunk predicted mass	2.0	11.3	15.2	2.6	-3.5	3.9
Leg fat mass (right)	2.0	7.8	10.8	2.6	-2.4	3.3
Arm predicted mass (right)	2.0	10.5	14.9	2.4	-3.3	3.9
Leg fat mass (left)	2.0	7.8	10.6	2.6	-2.5	3.3
Arm predicted mass (left)	2.0	10.0	13.3	2.1	-3.5	3.6
Depressed Affect (Nagel 2018)	1.9	4.1	7.2	1.8	-1.4	2.7
Tense / ‘highly strung’	1.9	3.1	5.5	1.7	-1.0	2.4
Hair/balding pattern: Pattern 4	1.9	4.5	13.1	-0.4	-0.5	-3.6
Glaucoma (self-reported)	1.9	2.3	3.2	1.2	-1.8	1.4
Overall health rating	1.9	4.1	7.2	2.7	-1.5	1.7
Ever had prostate specific antigen (PSA) test	1.9	2.2	5.8	0.4	-0.8	2.4
Body Mass Index (BMI) (2010)	1.8	2.5	3.0	1.4	-1.7	1.6
Diabetes (father)	1.8	2.3	5.6	-2.4	0.6	-0.9
Stomach or abdominal pain in last month	1.8	2.2	4.2	-1.0	1.2	-2.0
Waist circumference	1.8	6.7	10.9	2.5	-1.7	3.3
Exposure to tobacco smoke at home	1.8	2.0	2.6	1.6	-1.6	1.0
Arm fat-free mass (right)	1.8	9.3	12.7	2.3	-3.1	3.6
Pulse rate, automated reading	1.8	5.9	8.9	-2.3	1.9	-3.0
Ever had bowel cancer screening	1.8	2.1	3.6	0.5	1.9	1.6
Medication: Gliclazide	1.8	2.0	4.0	1.3	-0.6	2.0
Whole body water mass	1.8	10.0	14.4	2.5	-3.1	3.8
Basal metabolic rate	1.8	10.1	14.6	2.5	-3.1	3.8
Basal cell carcinoma (self-reported)	1.8	2.1	6.0	-0.5	-0.5	-2.4
Major Depression (MDD)	1.7	2.1	4.3	2.1	0.5	1.3
Other serious medical condition/disability diagnosed by doctor	1.7	2.3	3.8	1.9	-0.3	1.7
Financial difficulties in last 2 years	1.7	2.3	3.7	1.9	0.7	1.6
Arm fat percentage (right)	1.7	6.7	10.4	2.8	-1.3	3.2
Falls in the last year	1.7	2.3	4.8	1.2	-0.8	2.2
Pulse rate	1.7	2.8	4.3	-1.3	1.6	-2.1
Whole body fat-free mass	1.7	9.9	13.8	2.4	-3.1	3.7
Arm fat percentage (left)	1.7	6.9	10.2	3.0	-1.3	3.2
Pain type(s) experienced in last month: Hip pain	1.7	2.1	2.8	1.3	-1.4	1.7
Number of operations (self-reported)	1.7	2.5	6.4	-0.3	-2.5	-1.0
Father’s age at death	1.6	2.2	4.7	-0.8	2.2	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.4	3.8	2.0	0.5	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.3	6.9	1.3	1.2	2.6
High cholesterol (Self-reported)	1.6	2.8	4.6	2.1	-1.6	1.1
Arm fat-free mass (left)	1.6	8.3	11.7	2.0	-3.0	3.4
Age started oral contraceptive pill	1.6	2.1	2.9	-1.3	1.3	-1.7
Vascular/heart problems diagnosed by doctor	1.6	4.3	8.2	-2.9	1.8	-1.2
Frequency of depressed mood in last 2 weeks	1.5	2.0	4.7	0.8	0.9	2.2
Qualifications: A levels/AS levels or equivalent	1.5	3.4	7.8	1.5	0.3	2.8
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	3.6	1.1	0.6	1.9
Number of children fathered	1.5	1.7	5.1	-0.2	-2.3	-0.3
Health satisfaction	1.5	1.9	3.5	1.1	-1.9	1.0
Whole body fat mass	1.5	6.4	8.1	2.5	-2.2	2.8
Lung FEV1/FVC ratio	1.4	7.2	11.2	-2.2	3.4	-2.3
Severe depression (siblings)	1.4	1.6	2.4	1.6	-1.4	-0.6
Alcohol usually taken with meals	1.4	2.3	4.5	-2.1	1.0	-1.2
Hair/balding pattern: Pattern 2	1.4	1.8	3.0	1.7	-0.9	1.3
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	5.2	-0.5	-2.3	0.2
Migraine (self-reported)	1.4	1.7	3.8	-2.0	-0.0	-1.1
Supplements: Vitamin C	1.4	1.6	3.9	-0.3	2.0	1.0
Illnesses of father: Heart disease	1.4	1.9	4.5	2.1	-0.3	1.1
Average weekly red wine intake	1.4	2.1	3.0	1.7	-0.9	1.6
Qualifications: nursing, teaching	1.4	2.2	4.4	1.3	-0.8	2.1
Back pain experienced in last month	1.4	2.0	4.4	2.1	-0.7	1.1
Schizophrenia (2014)	1.3	3.0	5.7	1.7	-2.4	0.4
Cardiovascular Disease	1.3	4.2	6.9	2.6	-2.2	1.0
Hand grip strength (left)	1.3	3.4	6.5	-2.5	-1.3	-1.4
Fed-up feelings	1.3	2.4	4.7	1.6	-0.2	2.2
High blood pressure	1.3	3.7	6.7	2.6	-1.8	1.0
Leg predicted mass (left)	1.3	6.8	11.0	2.1	-2.2	3.3
Had other major operations	1.3	1.6	3.5	-1.2	0.0	-1.9
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	5.4	0.5	-0.8	2.3
Happiness	1.3	1.6	1.9	1.4	-1.3	1.0
Medication: Lansoprazole	1.3	1.4	3.1	1.0	-1.8	0.5
Lung cancer (father)	1.3	1.6	2.9	1.4	-1.7	-0.0
Breast cancer (self-reported)	1.3	1.5	3.5	0.1	-1.9	-1.1
Depression (Nagel 2018)	1.2	1.9	4.5	0.8	0.7	2.1
Vitamin and mineral supplements	1.2	1.6	2.6	1.5	-1.6	-0.0
Leg fat-free mass (left)	1.2	6.5	10.4	2.1	-2.2	3.2
Medication: Cholesterol lowering	1.2	1.9	3.3	1.8	-0.9	1.3
Commuting to job workplace: Car/motor vehicle	1.2	1.3	2.6	0.2	-1.6	1.2
Leg predicted mass (right)	1.2	6.5	9.9	2.2	-2.2	3.1
Systolic Blood Pressure	1.1	5.6	12.9	-2.0	-0.3	-3.6
Smoking Status	1.1	2.6	3.8	1.5	-1.9	1.3
Average weekly fortified wine intake	1.1	1.3	2.7	-1.0	0.5	-1.6
Trunk fat mass	1.1	4.9	5.9	2.1	-2.1	2.4
Had menopause	1.1	1.3	3.6	1.9	0.3	0.6
Allergy	1.1	2.5	5.3	-0.4	-1.4	-2.3
Worrier / anxious feelings	1.1	2.2	5.2	0.0	2.3	1.1
Leg fat percentage (right)	1.1	4.0	4.5	2.0	-1.9	2.1
Number of full brothers	1.1	1.4	3.0	1.7	0.1	1.1
Eye problems/disorders: None of the above	1.1	1.3	2.0	0.3	1.3	-1.4
Hypertension (Self-reported)	1.1	3.2	5.0	2.2	-2.0	0.8
Leg fat-free mass (right)	1.1	6.1	9.5	2.1	-2.1	3.1
Commuting to job workplace: Public transport	1.1	1.4	2.5	1.2	0.4	1.6
Leg fat percentage (left)	1.1	4.0	4.4	2.1	-1.9	2.1
Ulcerative Colitis (UC)	1.0	1.8	3.6	1.9	0.2	1.3
Ever highly irritable/argumentative for 2 days	1.0	1.2	2.0	0.4	-1.4	1.2
Emphysema/chronic bronchitis	1.0	1.2	1.7	0.6	-1.3	1.2
Medication: Ibuprofen	1.0	1.2	3.4	-0.3	-1.8	-0.1
Medication: Omeprazole	1.0	1.2	3.5	-0.3	0.1	-1.9
Osteoporosis (self-reported)	1.0	1.2	3.3	-0.3	1.8	0.3
Osteoarthritis (self-reported)	1.0	1.3	1.5	1.1	-1.2	1.1
Medication: Lisinopril	1.0	1.3	2.9	0.8	-1.7	0.6
Prostate Cancer	0.9	1.2	3.0	-0.6	-0.5	-1.7
Ulcerative Colitis	0.9	1.3	2.6	1.6	-0.8	0.9
Lung FVC	0.9	4.6	13.1	0.7	-0.2	3.6
Hand grip strength (right)	0.9	2.5	6.1	-2.5	-0.5	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	2.5	1.2	0.2	1.6
Breastfed as a baby	0.9	1.1	1.9	1.4	-1.0	0.6
Loud music exposure frequency	0.9	1.0	1.3	1.1	1.1	0.6
Medication for pain relief, constipation, heartburn	0.9	1.5	3.3	0.5	1.8	1.0
Heart disease (mother)	0.9	1.1	2.9	1.7	-0.0	0.6
Commuting to job workplace: Walk	0.9	1.0	2.4	-0.7	0.2	-1.6
Illnesses of father: None of the above (group 1)	0.9	1.1	2.1	-1.0	-1.5	-0.5
Miserableness	0.9	1.6	3.2	1.2	-0.4	1.8
Schizophrenia (2018)	0.8	1.7	3.4	1.3	-1.8	-0.1
Hayfever, allergic rhinitis or eczema	0.8	1.8	4.8	-0.7	2.2	0.4
Mouth/teeth dental problems	0.8	1.2	3.3	0.5	-1.8	0.1
Diabetes (self-reported)	0.8	1.2	2.0	1.2	0.1	1.4
Medication: Simvastatin	0.8	1.2	1.8	0.2	1.3	-1.3
Illnesses of mother	0.8	1.0	1.5	0.4	-1.2	1.2
Headache pain in last month	0.8	1.4	2.3	-0.4	1.3	-1.5
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	2.2	-1.3	1.5	-0.4
Medication: Ventolin 100micrograms inhaler	0.8	1.1	2.8	0.6	0.1	1.7
Body fat percentage	0.8	3.3	4.0	2.0	-1.5	2.0
Chest pain or discomfort	0.8	1.2	2.2	0.3	1.1	1.5
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.6	-0.6	1.9	0.1
Bipolar Disorder (2018)	0.7	1.2	3.2	-0.5	-0.3	-1.8
Neuroticism (2016)	0.7	1.0	2.8	0.5	-0.0	1.7
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.0	1.4	0.2	0.7
Medication for hormone replacement therapy	0.7	0.8	1.9	0.6	-1.4	-0.4
Supplements: Zinc	0.7	0.8	1.8	-0.5	-1.4	0.6
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	1.7	1.3	1.3	0.3
Had major operations	0.7	0.8	1.3	1.1	-1.0	0.3
Medication: Aspirin	0.7	0.9	1.5	1.2	-1.1	0.1
Heart disease (siblings)	0.7	0.9	2.3	0.0	0.5	1.5
Alcohol drinker status: Previous	0.7	0.8	1.0	0.8	0.9	1.0
Bipolar Disorder or Schizophrenia	0.6	1.5	2.7	0.7	-1.7	-1.2
Triglycerides	0.6	1.0	1.9	0.7	-1.4	0.7
Blood Eosinophil Count	0.6	4.4	6.0	2.4	-1.3	2.4
Hypothyroidism (self reported)	0.6	1.4	2.2	0.1	-1.5	1.5
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.4	-1.0	-0.4	-1.2
Diabetes (mother)	0.6	0.7	2.1	1.4	-0.3	0.2
Relative age voice broke	0.6	1.0	2.3	-1.5	0.5	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.5	2.9	1.7	-0.4	1.2
Serious illness, injury or assault to yourself	0.6	0.7	1.9	0.0	-1.4	-0.5
Supplements: Glucosamine	0.6	0.7	1.6	-0.1	-0.8	-1.3
Medication: Atenolol	0.6	0.7	1.7	-0.2	-0.7	-1.3
Medication: Levothyroxine sodium	0.6	1.1	2.6	0.2	-0.8	1.6
Pain all over the body in last month	0.6	0.6	1.2	-0.3	-1.1	0.7
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	1.5	-0.8	1.2	0.1
Depression (self-reported)	0.6	0.7	1.9	0.4	-0.3	1.4
Birth weight	0.6	1.3	2.0	-1.3	1.4	-0.3
Exposure to tobacco smoke outside home	0.6	0.8	1.8	1.3	-0.6	-0.5
Comparative body size at age 10	0.6	1.7	2.6	1.6	-0.5	1.5
Medication: Allopurinol	0.6	0.8	1.1	-0.8	0.8	-1.0
Leg pain on walking	0.6	0.8	2.1	-0.4	-1.4	0.1
Medication: Aspirin	0.6	0.7	1.2	1.0	-1.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	2.0	-1.4	-0.7	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.2	-0.7	-0.7	1.1
Supplements: Fish oil (including cod liver oil)	0.6	0.7	1.1	-1.1	0.0	-1.1
Medication: Bendroflumethiazide	0.6	0.9	2.6	1.6	-0.3	0.3
Fractured/broken bones in last 5 years	0.6	0.8	1.3	-1.0	-0.2	-1.1
Unable to work because of sickness or disability	0.6	0.8	2.3	-0.2	-1.5	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.9	0.2	-0.4	-1.4
Supplements: Calcium	0.6	0.7	1.8	-0.4	-1.3	-0.3
Irritable Bowel Disease (IBD)	0.5	1.1	2.0	1.4	1.1	0.4
Tanning	0.5	5.7	10.7	-2.3	-1.2	-3.3
Sensitivity / hurt feelings	0.5	0.9	2.3	0.5	-0.3	1.5
Trunk fat percentage	0.5	1.9	2.5	1.4	-1.1	1.6
High blood pressure (mother)	0.5	0.7	1.4	-0.5	0.7	-1.2
Illnesses of siblings	0.5	0.7	2.0	-0.2	-1.4	0.1
Hair/balding pattern: Pattern 3	0.5	0.8	2.3	0.3	0.2	1.5
Pulse wave reflection index	0.5	0.6	1.1	-0.5	1.0	0.6
High blood pressure (siblings)	0.5	0.7	1.3	0.8	1.2	0.4
Neck or shoulder pain in last month	0.5	0.7	1.2	-1.1	-0.9	-0.4
Suffer from ‘nerves’	0.5	0.8	1.7	-1.3	0.4	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.7	0.3	-0.2	-1.3
Diabetes diagnosed by doctor	0.5	0.8	1.7	0.8	-0.1	1.3
Wears glasses or contact lenses	0.5	0.6	1.3	-1.1	-0.7	0.1
Cholesterol lowering medication	0.5	0.7	1.7	0.3	1.3	-0.7
Worry (Nagel 2018)	0.4	0.9	2.6	0.2	-0.0	1.6
Crohns Disease (2017)	0.4	0.9	2.1	-0.2	1.5	-0.7
Coronary Artery Disease (CAD)	0.4	0.5	1.1	-0.4	-1.0	0.5
HbA1C	0.4	0.4	0.9	0.5	-0.3	0.9
HDL Cholesterol	0.4	0.6	1.0	-0.3	1.0	0.8
Blood Platelet Count	0.4	4.1	6.3	-1.0	-2.5	-2.2
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.3	0.8	0.8	1.1
Hearing difficulty/problems: Yes	0.4	0.6	0.8	0.9	-0.7	0.7
Relative age of first facial hair	0.4	0.9	1.8	-1.3	0.9	-0.2
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.1	0.5	-0.3	1.1
Angina	0.4	0.6	1.4	1.2	-0.5	0.4
Medication: Co-codamol	0.4	0.4	0.5	0.7	-0.7	0.4
Nervous feelings	0.4	0.8	1.7	-0.3	0.8	1.3
Medication: Amlodipine	0.4	0.6	0.7	-0.7	-0.7	-0.8
Age at first live birth	0.4	0.7	1.0	-0.7	0.6	-1.0
Pulse wave peak to peak time	0.4	0.5	0.6	0.3	-0.8	-0.8
Number of full sisters	0.4	0.5	1.0	0.4	-0.7	1.0
Schizophrenia vs Biploar Disorder	0.3	0.4	1.0	0.1	-0.6	1.0
Alzheimer’s Disease (in mother)	0.3	0.4	0.9	-0.4	0.4	-0.9
Ovarian Cancer	0.3	0.4	0.9	0.3	-1.0	0.6
Fasting Glucose	0.3	0.4	1.1	-0.1	-0.1	-1.1
Blood White Count	0.3	1.9	3.0	1.3	-1.7	1.0
Ever had hysterectomy (womb removed)	0.3	0.3	0.9	0.3	-0.1	-0.9
Townsend deprivation index at recruitment	0.3	0.4	0.5	-0.5	0.7	-0.7
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.9	-0.0	-1.0	-0.4
Chronic bronchitis/emphysema (father)	0.3	0.4	0.5	0.5	0.7	0.6
Medication: Ramipril	0.3	0.4	1.0	0.5	1.0	-0.1
Alcohol intake versus 10 years previously	0.3	0.4	0.7	0.6	-0.5	0.8
Number of live births	0.3	0.5	0.7	-0.8	-0.4	-0.8
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	2.4	-1.6	0.0	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	1.2	-0.9	0.6	1.1
Pulse wave Arterial Stiffness index	0.3	0.4	0.8	-0.2	0.6	0.9
Standing height	0.3	3.3	4.7	-2.2	-1.9	-1.2
Gout (self-reported)	0.3	0.4	0.9	-0.5	-0.9	0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.2	0.0	-0.8	1.1
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.5	0.7	-0.4	0.5
Medication: Blood pressure	0.3	0.4	0.7	0.9	-0.8	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	0.7	0.5	0.0	-0.8
Comparative height size at age 10	0.3	1.6	4.5	0.0	-2.1	-0.3
Age at last live birth	0.3	0.4	0.6	-0.5	0.7	-0.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.8	-0.9	0.5	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.7	0.6	-0.0	0.8
Medication for cholesterol	0.3	0.5	1.2	-1.1	0.2	0.5
Mineral and other dietary supplements	0.3	0.4	0.7	0.4	0.6	0.8
Hearing aid user	0.3	0.3	0.6	-0.6	-0.4	-0.8
Alcohol drinker status: Never	0.3	0.4	0.5	-0.4	0.7	-0.7
Breast Cancer	0.2	0.5	0.6	0.3	0.8	0.8
Crohns Disease (2012)	0.2	0.3	1.0	-0.1	-0.0	-1.0
Allergy or Eczema	0.2	0.5	0.9	0.0	0.7	1.0
Maternal smoking around birth	0.2	0.3	0.4	-0.5	0.4	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.5	-0.2	0.7	0.6
Age when periods started (menarche)	0.2	0.6	0.9	-0.9	-0.2	-0.9
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	0.6	0.4	0.4
Sitting height	0.2	1.2	2.8	-1.7	-0.9	-0.3
Number of incorrect matches in round	0.2	0.3	0.7	-0.4	-0.1	-0.8
Hearing difficulty/problems with background noise	0.2	0.3	0.8	0.2	0.3	-0.9
Forced vital capacity (FVC)	0.2	0.9	1.2	-0.7	-1.0	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	0.8	0.9	0.8	0.6
Mouth/teeth dental problems: Dentures	0.2	0.3	0.7	-0.2	0.2	0.8
Prospective memory result	0.2	0.3	0.5	-0.1	-0.5	-0.7
Forced vital capacity (FVC), Best measure	0.2	0.8	2.2	-0.5	-0.1	1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.5	0.2	-0.3	0.7
Angina (self-reported)	0.2	0.3	0.9	1.0	-0.2	0.1
Knee pain experienced in last month	0.2	0.2	0.4	0.6	-0.4	0.3
Illnesses of siblings: Diabetes	0.2	0.2	0.5	0.3	0.7	0.1
Eye problems/disorders: Cataract	0.2	0.3	0.5	-0.7	-0.2	0.5
Mother’s age at death	0.2	0.3	0.3	0.6	0.5	0.6
Medication: Blood pressure	0.2	0.4	1.2	-0.0	-0.3	-1.1
Myopia	0.2	0.3	0.8	0.2	-0.2	0.9
Pain experienced in last month	0.2	0.4	1.1	-0.2	1.0	-0.2
Pack years of smoking	0.2	0.3	0.5	0.4	0.6	-0.7
Age at First Birth	0.1	0.2	0.5	0.1	0.7	0.3
Mean Putamen Volume	0.1	0.1	0.2	-0.4	-0.0	0.5
Rheumatoid Arthritis	0.1	0.1	0.3	0.6	0.2	-0.2
Heel T-Score	0.1	0.4	0.8	-0.1	-0.6	-0.9
Height	0.1	2.4	5.5	-2.3	-0.6	-1.2
Hair Pigment	0.1	3.5	4.2	2.0	-1.5	2.0
Average weekly spirits intake	0.1	0.1	0.1	-0.1	0.4	-0.3
Systolic blood pressure, automated reading	0.1	0.2	0.2	0.4	-0.4	-0.5
Pack years adult smoking proportion	0.1	0.2	0.5	0.7	0.4	-0.1
Current tobacco smoking	0.1	0.1	0.2	0.4	0.3	-0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.4	-0.1	0.3	0.6
Blood clot in the leg (DVT)	0.1	0.2	0.4	0.3	-0.6	-0.0
Alcohol intake frequency.	0.1	0.2	0.3	0.5	0.4	0.6
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.2	-0.4	0.4	-0.4
Mood swings	0.1	0.2	0.6	0.2	-0.1	0.8
Average weekly champagne plus white wine intake	0.1	0.2	0.4	0.1	0.7	-0.3
Medication: Atorvastatin	0.1	0.1	0.2	0.4	-0.2	0.5
Illnesses of father: High blood pressure	0.1	0.2	0.4	-0.2	0.7	-0.1
Average weekly beer plus cider intake	0.1	0.1	0.3	-0.2	0.5	0.2
Commuting to job workplace: Cycle	0.1	0.1	0.3	0.2	0.2	-0.6
Lupus	0.0	0.0	0.1	-0.3	-0.1	-0.0
Blood Red Count	0.0	0.3	0.5	0.7	-0.2	-0.5
Smoking status: Current	0.0	0.0	0.1	0.4	0.1	-0.1
Diastolic blood pressure, automated reading	0.0	0.0	0.1	0.1	0.2	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.0	0.1	0.2	0.0	-0.1	-0.4

Hub : Genes

HBEGF

Models

Trait associations