[Hub]/) : Traits : Reaction Time :

chr12:48,605,088-50,199,949

Best TWAS P=5.45e-11 · Best GWAS P=2.43e-12 conditioned to 0.00457

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RHEBL1 0.03 0.01 blup 315 0.02 4.4e-03 6.6 5.2 2.4e-07 0.64 0.03 0.87 FALSE
2 GTEx Artery Aorta CCDC65 0.19 0.08 enet 7 0.11 1.9e-06 3.9 6.6 5.4e-11 0.82 0.02 0.98 TRUE
3 GTEx Artery Tibial CCDC65 0.14 0.08 enet 39 0.11 7.9e-09 7.0 6.6 5.6e-11 0.80 0.01 0.99 FALSE
4 GTEx Esophagus Mucosa LMBR1L 0.07 0.03 lasso 5 0.04 1.8e-03 5.3 -6.0 1.7e-09 -0.72 0.02 0.96 FALSE
5 GTEx Lung LMBR1L 0.05 0.02 lasso 2 0.00 1.5e-01 5.3 -5.3 1.1e-07 -0.61 0.14 0.21 FALSE
6 GTEx Muscle Skeletal RP11-386G11.5 0.09 0.07 enet 17 0.08 7.4e-08 5.6 -5.6 1.7e-08 -0.78 0.29 0.71 FALSE
7 GTEx Nerve Tibial LMBR1L 0.08 0.04 lasso 4 0.06 3.1e-05 5.8 -5.5 3.6e-08 -0.65 0.60 0.26 FALSE
8 GTEx Testis PRKAG1 0.17 0.11 lasso 5 0.09 1.2e-04 5.3 -5.6 2.0e-08 -0.69 0.18 0.78 FALSE