Best TWAS P=7.28e-08 · Best GWAS P=1.72e-07 conditioned to 0.512
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | TRPT1 | 0.24 | 0.26 | lasso | 6 | 0.27 | 1.6e-26 | 5.1 | 5.4 | 7.3e-08 | 0.92 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FERMT3 | 0.04 | 0.04 | lasso | 3 | 0.04 | 3.2e-05 | 5.1 | -5.2 | 2.1e-07 | -0.99 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MACROD1 | 0.03 | 0.04 | lasso | 2 | 0.03 | 4.6e-04 | 5.2 | 5.2 | 1.6e-07 | 0.99 | 0.01 | 0.94 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | DNAJC4 | 0.03 | 0.03 | lasso | 1 | 0.02 | 2.4e-03 | 5.1 | -5.1 | 2.9e-07 | -0.97 | 0.00 | 0.93 | FALSE |