Best TWAS P=1.09e-11 · Best GWAS P=2.77e-21 conditioned to 8.21e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | U91328.21 | 0.09 | 0.01 | lasso | 8 | 0.01 | 0.0300 | 2.02 | 6.8 | 1.1e-11 | -0.50 | 0.30 | 0.10 | TRUE |
2 | GTEx | Skin Sun Exposed Lower leg | TRIM38 | 0.09 | 0.00 | enet | 21 | 0.02 | 0.0063 | -0.75 | 5.1 | 2.9e-07 | -0.51 | 0.10 | 0.71 | TRUE |
3 | The Cancer Genome Atlas | Lung Adenocarcinoma | TRIM38 | 0.07 | 0.01 | lasso | 6 | 0.02 | 0.0051 | 2.14 | 6.7 | 2.2e-11 | -0.50 | 0.01 | 0.56 | FALSE |