Best TWAS P=7.1e-09 · Best GWAS P=1.76e-06 conditioned to 0.18
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LGSN | 0.06 | 0.04 | blup | 44 | 0.04 | 1.2e-08 | 4.8 | 5.8 | 7.1e-09 | 0.65 | 0.00 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | LGSN | 0.05 | 0.05 | enet | 10 | 0.04 | 7.6e-06 | -4.2 | 5.3 | 1.2e-07 | 0.70 | 0.02 | 0.93 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LGSN | 0.19 | 0.11 | enet | 11 | 0.14 | 2.6e-14 | 4.2 | 5.4 | 8.5e-08 | 0.62 | 0.03 | 0.91 | FALSE |