Best TWAS P=1.39e-08 · Best GWAS P=2.04e-10 conditioned to 0.00106
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Sigmoid | IMMP2L | 0.12 | 0.05 | lasso | 3 | 0.05 | 8.5e-03 | 5.2 | 5.3 | 1.1e-07 | -0.71 | 0.31 | 0.32 | FALSE |
| 2 | GTEx | Thyroid | IMMP2L | 0.16 | 0.08 | lasso | 6 | 0.07 | 8.1e-06 | 5.4 | -5.7 | 1.4e-08 | 0.72 | 0.36 | 0.64 | TRUE |
| 3 | GTEx | Whole Blood | IMMP2L | 0.06 | 0.06 | lasso | 4 | 0.04 | 1.4e-04 | -5.1 | -5.3 | 1.4e-07 | 0.90 | 0.02 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | IMMP2L | 0.05 | 0.02 | blup | 312 | 0.04 | 4.5e-05 | -3.7 | -5.2 | 1.9e-07 | 0.79 | 0.10 | 0.86 | FALSE |