Best TWAS P=4.91e-10 · Best GWAS P=1.33e-13 conditioned to 8.19e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | CACNA2D4 | 0.19 | 0.04 | lasso | 5 | 0.01 | 9.2e-02 | 7.1 | -6.2 | 4.9e-10 | -0.89 | 0.04 | 0.46 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | DCP1B | 0.08 | 0.00 | blup | 553 | 0.04 | 1.8e-05 | 3.9 | -5.2 | 1.7e-07 | -0.32 | 0.08 | 0.16 | TRUE |