[Hub]/) : Traits : Schizophrenia (2018) :

chr14:70,676,661-72,273,020

Best TWAS P=4.44e-09 · Best GWAS P=2.89e-08 conditioned to 0.813

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PCNX 0.17 0.21 lasso 3 0.22 1.9e-17 5.0 -5.3 1.1e-07 -0.88 0.06 0.94 FALSE
2 GTEx Adipose Visceral Omentum PCNX 0.09 0.04 lasso 2 0.03 9.9e-03 5.4 -5.4 5.1e-08 -1.00 0.01 0.96 FALSE
3 GTEx Artery Aorta PCNX 0.26 0.32 enet 32 0.29 3.7e-16 5.0 -5.5 4.8e-08 -0.84 0.11 0.89 FALSE
4 GTEx Artery Tibial PCNX 0.21 0.32 lasso 5 0.31 6.7e-25 5.0 -5.2 2.3e-07 -0.86 0.12 0.88 FALSE
5 GTEx Breast Mammary Tissue (Male) PCNX 0.11 0.11 lasso 3 0.07 1.3e-02 5.3 -5.4 7.7e-08 -0.93 0.03 0.70 FALSE
6 GTEx Cells Transformed fibroblasts PCNX 0.14 0.06 enet 28 0.10 1.2e-07 4.8 -5.2 2.0e-07 -0.72 0.04 0.96 FALSE
7 GTEx Esophagus Mucosa PCNX 0.20 0.18 enet 18 0.20 2.4e-13 5.3 -5.6 1.8e-08 -0.93 0.01 0.99 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic PCNX 0.18 0.18 lasso 4 0.19 1.7e-10 5.0 -5.5 4.2e-08 -0.92 0.01 0.99 FALSE
9 GTEx Skin Sun Exposed Lower leg PCNX 0.23 0.29 enet 30 0.29 2.1e-24 5.0 -5.6 2.8e-08 -0.87 0.15 0.85 FALSE
10 GTEx Testis PCNX 0.14 0.09 enet 12 0.07 3.2e-04 4.9 -5.4 5.9e-08 -0.92 0.02 0.98 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma PCNX 0.05 0.04 blup 92 0.04 4.2e-09 5.5 -5.3 1.1e-07 -0.89 0.01 0.99 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma PCNX 0.06 0.06 blup 91 0.07 7.1e-08 4.5 -5.4 6.0e-08 -0.87 0.04 0.96 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma PCNX 0.08 0.06 blup 91 0.08 8.8e-08 5.5 -5.9 4.4e-09 -0.93 0.01 0.99 TRUE