[Hub]/) : Traits : Schizophrenia (2018) :

chr14:103,161,201-105,211,221

Best TWAS P=4.26e-11 · Best GWAS P=5.79e-10 conditioned to 0.0326

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PPP1R13B 0.04 0.02 lasso 2 0.01 4.1e-02 5.5 -5.6 1.9e-08 -0.63 0.08 0.72 FALSE
2 GTEx Adipose Subcutaneous KLC1 0.05 0.03 lasso 3 0.03 1.8e-03 6.1 5.4 8.3e-08 0.86 0.03 0.89 FALSE
3 GTEx Adipose Subcutaneous XRCC3 0.09 0.08 lasso 5 0.07 3.8e-06 5.9 6.0 2.2e-09 0.95 0.01 0.99 FALSE
4 GTEx Adipose Subcutaneous APOPT1 0.06 0.02 lasso 5 0.02 8.2e-03 5.4 -6.0 2.3e-09 -0.91 0.04 0.92 FALSE
5 GTEx Adipose Subcutaneous RP11-73M18.8 0.14 0.19 lasso 4 0.20 6.4e-16 5.4 5.5 4.1e-08 0.86 0.08 0.92 FALSE
6 GTEx Adrenal Gland KLC1 0.15 0.03 lasso 3 0.06 4.6e-03 5.7 5.4 7.9e-08 0.80 0.06 0.65 FALSE
7 GTEx Artery Aorta ZFYVE21 0.10 0.09 lasso 4 0.08 2.9e-05 5.8 5.5 3.4e-08 0.64 0.08 0.74 FALSE
8 GTEx Artery Tibial XRCC3 0.06 0.08 lasso 3 0.03 1.4e-03 5.7 5.9 4.0e-09 0.74 0.10 0.89 FALSE
9 GTEx Artery Tibial RP11-73M18.8 0.09 0.06 lasso 4 0.09 7.4e-08 5.4 6.0 2.6e-09 0.82 0.05 0.95 FALSE
10 GTEx Artery Tibial RP11-73M18.6 0.05 0.03 lasso 2 0.02 4.7e-03 5.4 5.2 2.4e-07 0.83 0.05 0.82 FALSE
11 GTEx Brain Cortex XRCC3 0.12 0.02 lasso 4 0.01 1.7e-01 5.7 5.8 8.5e-09 0.74 0.08 0.61 FALSE
12 GTEx Brain Cortex RP11-73M18.8 0.35 0.13 enet 34 0.25 1.2e-07 5.9 5.5 3.1e-08 0.66 0.03 0.97 FALSE
13 GTEx Breast Mammary Tissue KLC1 0.12 0.02 enet 26 0.07 2.9e-04 5.7 6.0 2.0e-09 0.82 0.06 0.93 FALSE
14 GTEx Breast Mammary Tissue XRCC3 0.15 0.01 enet 37 0.01 1.0e-01 5.8 5.2 2.4e-07 0.66 0.07 0.92 FALSE
15 GTEx Breast Mammary Tissue RP11-73M18.8 0.19 0.14 enet 21 0.26 2.0e-13 6.2 5.8 5.4e-09 0.85 0.01 0.99 FALSE
16 GTEx Breast Mammary Tissue (Male) RP11-73M18.8 0.22 0.12 lasso 4 0.08 7.3e-03 5.8 5.6 2.4e-08 0.74 0.06 0.84 FALSE
17 GTEx Breast Mammary Tissue (Female) KLC1 0.09 0.00 lasso 2 0.00 2.4e-01 6.1 6.6 5.2e-11 0.93 0.04 0.64 FALSE
18 GTEx Cells EBV-transformed lymphocytes PPP1R13B 0.15 0.08 lasso 4 0.07 2.2e-03 5.8 -6.6 4.3e-11 -0.71 0.07 0.83 TRUE
19 GTEx Colon Transverse KLC1 0.16 0.01 lasso 7 0.00 1.9e-01 6.2 6.0 1.6e-09 0.95 0.02 0.86 FALSE
20 GTEx Colon Transverse XRCC3 0.13 0.14 lasso 4 0.11 1.0e-05 5.7 5.8 6.0e-09 0.81 0.07 0.93 FALSE
21 GTEx Esophagus Gastroesophageal Junction PPP1R13B 0.09 0.08 lasso 2 0.05 7.9e-03 5.8 -5.9 4.8e-09 -0.67 0.07 0.76 FALSE
22 GTEx Esophagus Gastroesophageal Junction RP11-73M18.8 0.14 0.07 enet 10 0.10 2.4e-04 5.4 5.9 2.9e-09 0.79 0.08 0.88 FALSE
23 GTEx Esophagus Mucosa KLC1 0.17 0.09 lasso 5 0.12 1.6e-08 5.7 5.9 4.9e-09 0.75 0.08 0.91 FALSE
24 GTEx Esophagus Mucosa XRCC3 0.12 0.15 lasso 2 0.13 4.4e-09 5.7 5.7 9.1e-09 0.82 0.10 0.90 FALSE
25 GTEx Esophagus Muscularis PPP1R13B 0.12 0.07 lasso 5 0.07 3.9e-05 5.6 -5.8 5.2e-09 -0.67 0.10 0.90 FALSE
26 GTEx Esophagus Muscularis KLC1 0.07 0.01 enet 10 0.02 2.6e-02 -3.5 5.8 6.3e-09 0.68 0.11 0.48 FALSE
27 GTEx Esophagus Muscularis XRCC3 0.11 0.05 enet 23 0.03 5.2e-03 5.4 5.8 8.4e-09 0.66 0.04 0.86 FALSE
28 GTEx Esophagus Muscularis RP11-73M18.8 0.11 0.04 enet 11 0.10 1.9e-06 5.7 5.6 2.4e-08 0.69 0.08 0.88 FALSE
29 GTEx Muscle Skeletal KLC1 0.11 0.07 lasso 7 0.08 3.3e-08 -3.5 5.2 1.7e-07 0.73 0.40 0.60 FALSE
30 GTEx Muscle Skeletal RP11-73M18.8 0.11 0.14 lasso 7 0.13 8.4e-13 5.2 5.8 5.6e-09 0.71 0.15 0.85 FALSE
31 GTEx Nerve Tibial KLC1 0.07 0.00 enet 22 0.01 8.5e-02 4.7 6.4 1.8e-10 0.73 0.07 0.78 FALSE
32 GTEx Nerve Tibial XRCC3 0.08 0.06 lasso 3 0.05 3.5e-04 5.4 5.7 1.3e-08 0.85 0.05 0.95 FALSE
33 GTEx Nerve Tibial APOPT1 0.10 0.08 lasso 5 0.06 7.8e-05 6.1 -6.0 1.7e-09 -0.98 0.01 0.99 FALSE
34 GTEx Nerve Tibial RP11-73M18.8 0.08 0.13 lasso 4 0.10 7.4e-08 5.4 5.4 7.0e-08 0.84 0.15 0.85 FALSE
35 GTEx Ovary RP11-73M18.8 0.19 0.20 lasso 5 0.14 2.4e-04 5.4 5.6 1.6e-08 0.80 0.06 0.74 FALSE
36 GTEx Pituitary RP11-73M18.8 0.23 0.17 lasso 2 0.13 3.6e-04 5.4 5.4 5.4e-08 0.85 0.05 0.66 FALSE
37 GTEx Prostate RP11-73M18.8 0.15 0.29 lasso 1 0.25 5.2e-07 5.7 5.7 1.5e-08 0.82 0.06 0.85 FALSE
38 GTEx Skin Not Sun Exposed Suprapubic KLC1 0.11 0.09 lasso 4 0.10 4.1e-06 5.7 5.9 4.1e-09 0.64 0.10 0.87 FALSE
39 GTEx Skin Not Sun Exposed Suprapubic XRCC3 0.14 0.03 lasso 14 0.03 1.3e-02 5.7 6.2 5.1e-10 0.80 0.05 0.94 FALSE
40 GTEx Skin Sun Exposed Lower leg XRCC3 0.09 0.10 enet 16 0.09 6.3e-08 5.8 5.5 4.3e-08 0.76 0.06 0.94 FALSE
41 GTEx Skin Sun Exposed Lower leg RP11-73M18.8 0.11 0.11 lasso 4 0.12 5.1e-10 5.4 5.2 2.5e-07 0.72 0.08 0.92 FALSE
42 GTEx Small Intestine Terminal Ileum ZFYVE21 0.16 0.10 lasso 2 0.13 7.7e-04 4.0 5.2 2.1e-07 0.61 0.07 0.45 FALSE
43 GTEx Spleen XRCC3 0.28 0.19 lasso 3 0.24 8.7e-07 5.7 5.3 1.2e-07 0.77 0.04 0.94 FALSE
44 GTEx Testis KLC1 0.17 0.17 lasso 2 0.15 4.4e-07 5.7 6.1 1.2e-09 0.82 0.10 0.89 FALSE
45 GTEx Testis RP11-73M18.8 0.16 0.12 lasso 4 0.12 4.0e-06 5.7 6.0 2.4e-09 0.82 0.09 0.89 FALSE
46 GTEx Thyroid KLC1 0.12 0.03 enet 22 0.03 3.6e-03 5.1 5.7 1.0e-08 0.61 0.12 0.73 FALSE
47 GTEx Thyroid APOPT1 0.11 0.12 lasso 1 0.10 1.9e-08 5.9 -5.9 3.8e-09 -0.97 0.01 0.99 FALSE
48 GTEx Whole Blood KLC1 0.16 0.13 lasso 3 0.11 3.6e-10 5.7 5.7 1.2e-08 0.83 0.11 0.89 FALSE
49 GTEx Whole Blood XRCC3 0.08 0.12 lasso 3 0.10 1.3e-09 5.7 5.8 8.5e-09 0.82 0.10 0.90 FALSE
50 METSIM Adipose MARK3 0.03 0.02 lasso 6 0.03 6.3e-05 5.9 -5.3 1.4e-07 -0.87 0.06 0.93 FALSE
51 METSIM Adipose TDRD9 0.08 0.04 lasso 10 0.06 1.9e-09 6.1 -5.4 5.3e-08 -0.81 0.01 0.99 FALSE
52 METSIM Adipose XRCC3 0.13 0.20 lasso 7 0.22 6.2e-33 5.7 5.5 3.7e-08 0.76 0.10 0.90 FALSE
53 YFS Blood BAG5 0.01 0.01 bslmm 350 0.00 1.9e-02 6.2 5.8 5.6e-09 0.73 0.01 0.92 FALSE
54 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma XRCC3 0.03 0.04 enet 3 0.04 6.1e-05 5.7 6.0 2.7e-09 0.82 0.02 0.97 FALSE
55 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma XRCC3 0.06 0.07 lasso 4 0.05 4.6e-04 5.7 5.6 2.4e-08 0.80 0.02 0.80 FALSE
56 The Cancer Genome Atlas Brain Lower Grade Glioma C14orf153 0.04 0.01 blup 38 0.03 6.2e-04 6.1 -5.4 5.1e-08 -0.84 0.00 0.95 FALSE
57 The Cancer Genome Atlas Lung Adenocarcinoma C14orf153 0.06 0.02 blup 38 0.04 2.4e-05 -3.4 -5.3 1.3e-07 -0.79 0.02 0.94 FALSE
58 The Cancer Genome Atlas Pancreatic Adenocarcinoma C14orf153 0.15 0.03 blup 37 0.03 1.6e-02 5.4 -5.6 2.3e-08 -0.91 0.01 0.78 FALSE
59 The Cancer Genome Atlas Prostate Adenocarcinoma XRCC3 0.02 0.01 blup 46 0.01 3.0e-02 5.3 5.7 1.3e-08 0.67 0.02 0.56 FALSE
60 The Cancer Genome Atlas Thyroid Carcinoma KLC1 0.04 0.01 blup 82 0.03 5.4e-04 6.1 6.1 1.2e-09 0.86 0.02 0.86 FALSE
61 The Cancer Genome Atlas Thyroid Carcinoma PPP1R13B 0.04 0.04 lasso 2 0.03 7.9e-04 5.7 5.8 6.0e-09 0.73 0.04 0.90 FALSE
62 The Cancer Genome Atlas Thyroid Carcinoma XRCC3 0.08 0.07 lasso 4 0.08 1.8e-08 5.7 5.4 5.3e-08 0.76 0.02 0.98 FALSE