[Hub]/) : Traits : Schizophrenia (2018) :

chr12:122,713,991-124,545,118

Best TWAS P=1.82e-09 · Best GWAS P=1.99e-09 conditioned to 0.0243

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts OGFOD2 0.10 0.07 lasso 7 0.07 3.1e-06 5.5 5.2 2.3e-07 0.93 0.09 0.91 FALSE
2 GTEx Cells Transformed fibroblasts ABCB9 0.08 0.12 enet 7 0.12 4.3e-09 5.3 5.4 7.3e-08 0.89 0.28 0.71 FALSE
3 GTEx Cells Transformed fibroblasts ARL6IP4 0.12 0.13 lasso 2 0.12 4.0e-09 5.3 -5.3 1.3e-07 -0.85 0.15 0.85 FALSE
4 GTEx Heart Left Ventricle ABCB9 0.10 0.14 lasso 5 0.10 4.2e-06 6.0 5.9 3.2e-09 0.95 0.01 0.99 FALSE
5 GTEx Liver ABCB9 0.32 0.32 lasso 3 0.28 1.9e-08 5.3 5.3 1.2e-07 0.88 0.12 0.85 FALSE
6 GTEx Pancreas ARL6IP4 0.07 0.07 lasso 2 0.07 9.6e-04 6.0 -5.4 6.1e-08 -0.93 0.04 0.88 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic ABCB9 0.13 0.15 lasso 11 0.11 2.1e-06 5.3 5.5 4.7e-08 0.93 0.03 0.97 FALSE
8 GTEx Skin Sun Exposed Lower leg ABCB9 0.09 0.08 lasso 5 0.08 4.3e-07 5.3 5.7 1.3e-08 0.93 0.03 0.97 FALSE
9 GTEx Testis MPHOSPH9 0.28 0.27 enet 23 0.32 1.3e-14 4.7 5.2 2.5e-07 0.93 0.07 0.93 FALSE
10 GTEx Testis CDK2AP1 0.20 0.14 lasso 5 0.13 2.0e-06 5.8 -5.9 3.3e-09 -0.95 0.01 0.99 FALSE
11 GTEx Testis RP11-282O18.3 0.18 0.09 lasso 9 0.12 7.8e-06 5.8 -5.3 1.3e-07 -0.85 0.02 0.96 FALSE
12 NTR Blood SBNO1 0.02 0.02 lasso 2 0.02 5.5e-07 5.2 -5.2 1.7e-07 -0.85 0.13 0.87 FALSE
13 The Cancer Genome Atlas Bladder Urothelial Carcinoma OGFOD2 0.03 0.02 blup 16 0.01 5.0e-02 5.2 5.4 5.3e-08 0.86 0.01 0.85 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma C12orf65 0.02 0.00 enet 6 0.01 2.4e-03 6.0 -5.6 1.7e-08 -0.82 0.01 0.81 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C12orf65 0.04 0.03 enet 18 0.03 4.9e-04 5.8 -6.0 1.8e-09 -0.75 0.01 0.91 TRUE
16 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C12orf65 0.05 0.04 blup 34 0.05 1.0e-03 5.3 -5.9 4.6e-09 -0.95 0.01 0.91 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma C12orf65 0.03 0.01 blup 35 0.02 1.6e-03 5.8 -5.8 5.9e-09 -0.89 0.01 0.87 FALSE
18 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ABCB9 0.19 0.22 enet 9 0.22 7.7e-11 5.2 5.7 1.6e-08 0.88 0.01 0.99 FALSE
19 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ABCB9 0.06 0.06 enet 7 0.07 5.2e-08 5.3 5.3 1.5e-07 0.91 0.01 0.99 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma ABCB9 0.04 0.05 enet 10 0.05 1.2e-05 5.0 5.2 2.1e-07 0.90 0.01 0.99 FALSE
21 The Cancer Genome Atlas Testicular Germ Cell Tumors CDK2AP1 0.13 0.10 blup 34 0.11 8.2e-05 5.8 -5.4 8.4e-08 -0.93 0.01 0.97 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma OGFOD2 0.02 0.00 enet 4 0.02 2.7e-03 5.3 5.6 2.2e-08 0.88 0.01 0.68 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma PITPNM2 0.04 0.03 enet 5 0.05 8.1e-06 3.7 5.7 1.2e-08 0.78 0.03 0.97 FALSE