Best TWAS P=1.29e-08 · Best GWAS P=5.39e-12 conditioned to 0.000631
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | ACTR5 | 0.59 | 0.60 | lasso | 9 | 0.63 | 1.5e-35 | -4.9 | -5.2 | 1.7e-07 | 0.74 | 0.98 | 0.02 | FALSE |
| 2 | YFS | Blood | ACTR5 | 0.16 | 0.14 | blup | 408 | 0.16 | 6.8e-50 | -4.1 | 5.7 | 1.3e-08 | -0.64 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ACTR5 | 0.04 | 0.06 | lasso | 4 | 0.06 | 5.4e-07 | -5.1 | -5.5 | 3.2e-08 | 0.83 | 0.19 | 0.80 | TRUE |