Best TWAS P=2.57e-08 · Best GWAS P=7.92e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | SREBF1 | 0.17 | 0.11 | lasso | 4 | 0.09 | 3.5e-04 | 5.0 | 5.1 | 2.7e-07 | 0.77 | 0.08 | 0.58 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TOM1L2 | 0.01 | 0.01 | blup | 83 | 0.01 | 1.8e-03 | 4.5 | -5.2 | 1.9e-07 | -0.92 | 0.07 | 0.77 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | LRRC48 | 0.07 | 0.05 | enet | 12 | 0.04 | 7.0e-03 | 5.0 | 5.3 | 9.1e-08 | 0.93 | 0.03 | 0.70 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | C17orf39 | 0.05 | 0.05 | blup | 49 | 0.05 | 5.8e-06 | 5.1 | 5.6 | 2.6e-08 | 0.98 | 0.03 | 0.97 | TRUE |