TWAS hub - ACTR5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0780	0.0330	2.4e-03	0.051	0.012	0.024	0.023	0.043	8.2e-07	1.0e-02	5.6e-04	6.7e-04	5.8e-06
2	GTEx	Artery Aorta	0.2380	0.0580	1.5e-07	0.203	NA	0.182	NA	0.199	1.9e-11	NA	2.8e-10	NA	3.3e-11
3	GTEx	Brain Cerebellar Hemisphere	0.3120	0.1150	9.3e-03	0.124	NA	0.088	NA	0.090	4.5e-04	NA	3.0e-03	NA	2.6e-03
4	GTEx	Breast Mammary Tissue	0.1200	0.0500	4.2e-03	0.127	NA	0.103	NA	0.111	4.6e-07	NA	5.9e-06	NA	2.5e-06
5	GTEx	Breast Mammary Tissue (Male)	0.0352	0.0504	2.8e-01	0.020	NA	-0.011	NA	-0.006	1.1e-01	NA	7.2e-01	NA	4.7e-01
6	GTEx	Breast Mammary Tissue (Female)	0.1454	0.0722	1.4e-02	0.124	NA	0.074	NA	0.119	1.5e-04	NA	3.2e-03	NA	2.1e-04
7	GTEx	Cells EBV-transformed lymphocytes	0.2820	0.0870	2.2e-04	0.100	NA	0.153	NA	0.160	3.8e-04	NA	1.1e-05	NA	6.8e-06
8	GTEx	Esophagus Mucosa	0.1110	0.0410	1.6e-03	0.085	NA	0.068	NA	0.096	2.5e-06	NA	2.4e-05	NA	5.5e-07
9	GTEx	Lung	0.1014	0.0354	3.1e-04	0.132	NA	0.121	NA	0.124	2.6e-10	NA	1.7e-09	NA	9.9e-10
10	GTEx	Skin Not Sun Exposed Suprapubic	0.1120	0.0470	6.0e-03	0.063	NA	0.051	NA	0.061	2.3e-04	NA	8.5e-04	NA	3.1e-04
11	GTEx	Skin Sun Exposed Lower leg	0.1170	0.0330	7.8e-07	0.117	NA	0.109	NA	0.124	6.4e-10	NA	2.5e-09	NA	2.0e-10
12	GTEx	Testis	0.5920	0.0520	0.0e+00	0.605	NA	0.632	NA	0.633	4.6e-33	NA	1.8e-35	NA	1.5e-35
13	GTEx	Whole Blood	0.0590	0.0240	3.6e-03	0.080	NA	0.044	NA	0.070	7.4e-08	NA	6.2e-05	NA	4.9e-07
14	METSIM	Adipose	0.0656	0.0229	2.5e-05	0.041	0.024	0.025	0.026	0.027	8.9e-07	1.2e-04	9.8e-05	6.5e-05	6.0e-05
15	YFS	Blood	0.1631	0.0270	0.0e+00	0.140	0.160	0.144	0.160	0.154	1.4e-43	6.8e-50	1.3e-44	7.3e-50	4.2e-48
16	TCGA	Brain Lower Grade Glioma	0.0412	0.0194	6.6e-05	0.059	0.050	0.048	NA	0.056	3.1e-07	2.2e-06	3.2e-06	NA	5.4e-07
17	TCGA	Liver Hepatocellular Carcinoma	0.1460	0.0700	5.0e-04	0.004	0.059	0.044	NA	0.047	2.0e-01	9.4e-04	3.8e-03	NA	2.8e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	6	7	8	9	10	11	12	13	14	15	16	17
Seen a psychiatrist for nerves, anxiety, tension or depression	13.1	17.0	24.7	2.9	4.9	4.2	4.7	4.9	4.0	3.9	4.8	4.8	4.5	-3.9	4.9	5.0	3.9	-3.9	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	9.4	14.4	20.5	3.5	4.4	4.3	4.5	4.5	3.9	3.8	4.5	4.3	3.8	-2.7	4.5	4.4	3.9	-2.7	-0.5
Family relationship satisfaction	9.1	11.2	15.9	3.3	4.0	3.1	4.0	3.9	3.3	3.7	3.8	3.7	3.8	-2.2	3.8	4.0	3.8	-2.5	-0.8
Schizophrenia (2018)	7.2	15.0	32.3	0.7	4.1	2.6	3.2	3.6	3.1	2.4	3.7	4.9	4.1	-5.2	3.8	4.2	5.7	-5.5	3.9
Bipolar Disorder or Schizophrenia	7.1	17.4	35.5	1.4	4.6	3.1	3.5	4.1	3.4	3.1	4.1	5.3	4.6	-5.3	4.2	4.7	6.0	-5.5	3.6
Reason for reducing amount of alcohol drunk: Health precaution	6.8	8.0	16.4	1.7	3.4	2.3	2.9	3.2	2.4	2.9	3.2	3.0	3.1	-2.8	3.2	3.3	4.0	-2.9	0.8
Number of incorrect matches in round	6.0	10.0	15.6	2.6	3.5	3.0	3.1	3.4	3.3	3.7	3.5	4.0	3.9	-2.3	3.5	3.6	3.7	-2.4	1.4
Happiness	5.3	6.5	11.8	2.4	2.9	3.4	3.2	3.2	2.3	2.6	3.2	2.4	2.3	-1.7	3.2	3.0	2.5	-1.5	-0.4
Health satisfaction	5.2	6.7	9.6	1.8	3.1	2.7	2.9	3.0	2.7	2.4	2.9	2.8	2.8	-2.5	2.9	3.1	2.9	-2.6	-0.3
Schizophrenia (2014)	5.1	11.3	26.0	0.2	3.5	1.9	2.4	3.1	2.4	1.8	3.2	4.1	3.3	-4.9	3.3	3.6	5.1	-5.0	3.7
Qualifications: NVQ or HND or HNC or equivalent	4.2	5.1	8.8	-2.2	-2.7	-2.2	-2.3	-2.4	-2.2	-2.9	-2.5	-2.4	-3.0	1.4	-2.5	-2.8	-2.5	1.7	0.4
Basal cell carcinoma (self-reported)	3.9	4.6	6.9	-1.3	-2.5	-2.1	-2.6	-2.6	-1.8	-2.3	-2.6	-2.3	-2.5	2.0	-2.6	-2.5	-2.5	1.9	-0.1
Qualifications: CSEs or equivalent	3.8	5.0	9.9	-1.4	-2.5	-1.7	-2.1	-2.3	-1.9	-2.4	-2.3	-3.1	-2.8	2.1	-2.3	-2.5	-3.1	2.4	-0.4
Birth weight	3.8	8.2	13.7	3.5	3.2	3.3	3.5	3.5	3.7	3.0	3.4	3.3	3.3	-1.0	3.4	3.2	1.1	-1.0	-0.7
Medication: Lisinopril	3.8	4.9	7.3	1.3	2.6	2.2	2.6	2.7	2.6	2.7	2.7	2.5	2.4	-2.1	2.6	2.5	1.7	-1.8	-0.0
Eye problems/disorders: Diabetes related eye disease	3.3	3.6	7.8	1.9	2.1	2.8	2.2	2.1	2.5	1.9	2.2	1.9	2.0	-1.2	2.2	2.2	1.4	-1.1	0.1
Smoking Status	3.2	7.8	14.3	1.7	3.2	2.1	2.7	3.0	3.1	1.4	2.8	3.3	3.2	-3.4	2.9	3.3	3.8	-3.7	0.5
Frequency of tenseness / restlessness in last 2 weeks	3.2	5.0	8.4	0.7	2.7	1.9	2.1	2.4	1.3	2.9	2.4	2.8	2.4	-2.6	2.4	2.7	2.2	-2.7	1.4
Ever unenthusiastic/disinterested for a whole week	3.2	3.9	7.0	2.2	2.3	2.1	2.2	2.4	2.7	2.1	2.4	1.8	1.8	-1.1	2.4	2.3	1.9	-0.7	0.3
Depression (self-reported)	3.2	3.8	6.6	1.7	2.3	2.1	2.1	2.2	1.4	2.3	2.2	2.3	2.6	-1.4	2.2	2.3	2.1	-1.5	0.1
Ever smoked	3.0	5.3	11.6	0.6	2.6	1.6	2.1	2.5	1.8	0.9	2.4	2.6	2.2	-3.3	2.5	2.5	3.4	-3.4	1.0
Heart disease (siblings)	3.0	3.7	6.8	-1.0	-2.3	-2.1	-2.1	-2.2	-1.4	-1.9	-2.0	-2.3	-2.6	2.1	-2.0	-2.4	-1.2	2.3	-0.7
Noisy workplace	2.9	3.6	7.6	-1.6	-2.1	-2.0	-2.1	-2.0	-2.3	-2.1	-1.9	-2.0	-2.8	1.1	-1.9	-2.2	-0.8	1.4	2.0
Angina (self-reported)	2.9	3.8	6.6	-0.7	-2.3	-1.9	-1.8	-2.0	-1.1	-2.0	-1.9	-2.5	-2.1	2.3	-1.9	-2.4	-1.8	2.6	-1.9
Number of full sisters	2.9	3.5	5.6	-1.5	-2.2	-2.2	-2.0	-2.2	-1.0	-2.3	-2.2	-2.4	-1.8	1.4	-2.2	-2.3	-1.8	1.4	-0.7
Angina	2.7	3.5	6.3	-0.8	-2.2	-1.8	-1.6	-1.9	-1.1	-2.0	-1.8	-2.5	-2.1	2.1	-1.8	-2.3	-1.8	2.4	-1.9
Chronic bronchitis/emphysema (father)	2.6	3.0	9.5	0.4	-1.8	-1.2	-0.8	-1.2	-1.5	-1.3	-1.3	-1.8	-2.4	2.8	-1.4	-1.9	-1.5	3.1	-2.4
Hair/balding pattern: Pattern 3	2.6	3.9	7.1	2.4	2.3	2.7	2.3	2.2	2.3	2.0	2.4	2.2	1.8	-0.9	2.4	2.3	1.3	-0.9	-1.0
Ever depressed for a whole week	2.6	3.2	6.7	1.9	2.0	1.9	2.0	2.2	2.6	1.7	2.1	2.0	1.9	-1.0	2.2	2.0	1.5	-0.8	0.1
Ovarian Cancer	2.5	3.2	4.6	-1.2	-2.0	-1.8	-1.8	-2.1	-1.8	-2.0	-2.0	-2.0	-2.0	1.6	-2.0	-1.9	-2.2	1.4	-1.5
Mean Putamen Volume	2.3	2.6	5.0	1.5	2.0	1.9	1.9	1.9	1.7	2.2	1.7	2.1	1.6	-1.0	1.7	1.9	1.0	-1.2	-0.5
Age at last live birth	2.3	3.3	7.6	1.6	2.0	1.6	2.0	2.0	0.7	2.7	1.9	2.8	1.8	-1.1	1.9	2.2	2.1	-1.4	0.8
Bipolar Disorder (2018)	2.2	3.6	6.1	1.3	2.2	1.7	1.6	2.0	1.6	1.9	2.0	2.3	2.3	-1.9	2.0	2.3	2.5	-1.9	0.9
Ulcerative Colitis (UC)	2.2	4.2	12.4	-0.4	2.2	1.9	1.9	2.2	1.6	0.5	2.1	1.4	1.9	-3.5	2.2	2.3	2.6	-3.3	1.1
Worrier / anxious feelings	2.2	4.1	6.9	2.6	2.2	2.2	2.6	2.4	2.4	2.2	2.5	1.4	2.1	-0.3	2.5	2.2	1.2	0.1	-1.9
Medication: Omeprazole	2.2	2.6	4.9	-1.0	-1.9	-2.0	-1.7	-1.9	-1.5	-1.3	-1.7	-1.7	-2.2	1.8	-1.7	-2.1	-1.2	1.8	-0.1
Average weekly spirits intake	2.1	2.6	4.5	-0.6	-1.7	-1.5	-2.0	-1.8	-2.0	-1.9	-1.6	-2.1	-2.1	1.6	-1.6	-1.8	-1.3	1.8	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	2.1	4.9	8.2	0.9	2.5	1.6	2.4	2.4	2.6	1.8	2.3	2.8	2.9	-2.4	2.3	2.5	2.3	-2.8	-0.5
Average weekly red wine intake	2.1	3.2	5.7	1.2	2.1	1.4	1.5	1.7	1.6	1.7	1.7	2.4	2.2	-2.1	1.7	2.3	1.6	-2.3	1.1
Risk taking	2.1	3.1	6.5	-2.5	-1.6	-2.0	-2.4	-2.0	-1.8	-2.4	-2.0	-1.3	-1.8	-0.6	-1.9	-1.6	-0.3	-0.7	2.4
Worry (Nagel 2018)	2.0	4.2	8.1	2.4	2.2	2.1	2.8	2.6	2.3	2.0	2.7	2.1	2.1	-0.7	2.6	2.3	1.6	-0.5	-1.2
Major Depression (MDD)	2.0	2.4	4.8	0.8	1.8	2.2	1.8	1.9	1.5	1.6	1.9	1.2	1.8	-1.6	1.9	1.8	0.7	-1.5	-0.0
Hearing difficulty/problems with background noise	2.0	3.1	9.3	3.0	1.6	1.9	1.9	1.8	2.2	2.6	1.9	1.4	1.3	0.9	1.9	1.6	0.5	1.1	-1.7
Medication: Omeprazole (e.g. Zanprol)	2.0	2.4	4.6	-0.9	-1.7	-1.8	-1.6	-1.8	-1.4	-1.3	-1.6	-1.9	-2.1	1.6	-1.6	-1.9	-1.4	1.7	-0.1
Severe depression (siblings)	1.9	2.1	3.7	0.8	1.7	1.1	1.3	1.6	1.5	1.5	1.5	1.9	1.5	-1.7	1.5	1.7	1.8	-1.7	0.3
Past tobacco smoking	1.9	3.6	8.1	-0.8	-2.1	-1.3	-1.9	-2.1	-1.9	-0.5	-1.9	-2.4	-1.8	2.5	-2.0	-2.0	-2.8	2.7	0.1
Father’s age at death	1.9	2.6	6.4	2.5	1.7	1.9	1.9	1.9	2.1	1.3	1.9	1.9	1.5	-0.1	2.0	1.6	0.6	-0.2	-1.3
Ever highly irritable/argumentative for 2 days	1.9	2.2	6.7	-2.6	-1.1	-1.0	-1.6	-1.3	-1.7	-1.9	-1.3	-1.6	-2.2	-1.1	-1.2	-1.1	-0.4	-0.7	2.2
Chest pain or discomfort	1.9	2.8	7.5	-0.9	-1.9	-2.0	-1.6	-1.7	-1.0	-1.4	-1.8	-1.2	-2.0	2.0	-1.8	-1.9	-2.7	1.7	-0.7
Medication: Atorvastatin	1.9	2.3	4.1	-1.1	-1.8	-1.5	-1.8	-1.7	-1.5	-1.2	-1.7	-1.5	-2.0	1.6	-1.7	-2.0	-1.2	1.6	0.4
Supplements: Glucosamine	1.8	2.4	4.8	-0.6	-1.8	-1.4	-1.7	-1.7	-1.5	-1.8	-1.5	-2.2	-1.8	1.6	-1.5	-1.7	-1.1	2.0	0.2
Birth weight of first child	1.8	3.2	7.9	2.4	1.7	1.5	2.1	1.9	2.8	2.2	1.8	2.8	2.3	0.1	1.8	1.7	0.1	-0.2	-0.6
Mouth/teeth dental problems: Bleeding gums	1.8	2.4	4.4	1.5	1.7	1.7	1.6	1.7	1.4	2.1	1.8	1.8	2.0	-0.8	1.8	1.7	1.7	-0.6	-0.4
Serious illness, injury or assault to yourself	1.7	2.1	3.3	-0.1	-1.6	-1.4	-1.7	-1.6	-0.9	-1.7	-1.6	-1.8	-1.2	1.6	-1.6	-1.6	-1.7	1.6	-1.0
Qualifications: College or University degree	1.7	5.4	12.8	0.4	2.5	1.4	1.8	2.2	1.6	2.6	2.1	3.6	2.4	-2.9	2.1	2.7	1.9	-3.6	2.6
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	3.5	0.7	1.6	1.6	1.5	1.5	0.8	1.1	1.4	1.9	1.3	-1.6	1.4	1.6	0.7	-1.8	0.1
Bipolar Disorder (2011)	1.6	1.6	3.6	1.2	1.4	1.1	1.3	1.4	1.1	1.4	1.4	1.8	1.4	-0.7	1.4	1.4	1.9	-0.8	-0.2
Maternal smoking around birth	1.6	2.4	5.0	1.0	1.9	0.9	1.4	1.4	1.8	1.4	1.4	1.9	2.2	-1.7	1.4	1.7	1.9	-2.0	-0.1
Diverticular disease/diverticulitis (self-reported)	1.6	1.9	5.1	-1.2	-1.6	-1.1	-1.3	-1.5	-2.2	-0.7	-1.4	-1.8	-1.9	1.4	-1.5	-1.6	-0.2	1.4	0.7
Smoking status: Previous	1.6	2.4	4.7	1.1	1.8	1.0	1.7	1.8	1.7	0.7	1.6	2.1	1.5	-1.6	1.6	1.7	2.2	-1.8	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.8	4.0	1.6	1.6	1.8	1.7	1.6	1.4	2.0	1.6	0.9	1.2	-0.4	1.6	1.6	1.0	-0.4	-0.5
Miserableness	1.6	2.7	7.8	1.7	1.9	2.8	2.1	2.1	1.3	1.7	2.2	1.2	1.5	-0.9	2.2	1.9	0.6	-0.3	-0.3
Townsend deprivation index at recruitment	1.5	2.1	5.9	-2.4	-1.3	-1.4	-1.1	-1.2	-2.3	-2.0	-1.4	-1.7	-1.9	-0.7	-1.3	-1.3	0.9	-0.6	0.4
Qualifications: None of the above	1.5	3.1	10.1	-1.4	-2.0	-1.5	-2.1	-1.8	-1.2	-2.3	-1.6	-3.2	-2.1	1.3	-1.6	-2.1	-0.7	2.0	-0.3
Pulse wave reflection index	1.5	1.9	5.5	1.1	1.4	1.6	1.5	1.6	1.6	2.3	1.8	0.8	1.6	-0.4	1.7	1.4	1.2	0.1	0.3
Financial situation satisfaction	1.5	1.9	3.0	0.5	1.5	1.7	1.6	1.5	1.0	1.4	1.5	1.4	1.0	-1.5	1.5	1.5	1.6	-1.4	1.4
Supplements: Calcium	1.5	1.7	3.9	-1.3	-1.3	-0.8	-1.7	-1.4	-1.3	-1.4	-1.2	-2.0	-1.5	0.8	-1.2	-1.4	-1.6	1.0	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.1	6.3	0.9	2.0	1.0	1.7	1.8	2.2	1.8	1.7	2.1	2.5	-1.6	1.8	2.0	2.2	-2.1	-0.6
Pain all over the body in last month	1.4	1.5	5.2	0.3	-1.3	-1.1	-0.7	-1.0	-0.3	-0.6	-0.8	-1.5	-1.1	2.1	-0.9	-1.3	-1.1	2.3	-1.7
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	5.1	1.7	1.7	1.7	1.7	1.5	0.8	2.3	1.4	1.9	1.9	-0.8	1.4	1.8	1.5	-1.1	0.2
Blood clot in the leg (DVT)	1.4	1.8	4.8	-1.7	-1.3	-1.6	-1.6	-1.5	-1.4	-1.6	-1.7	-0.8	-1.0	-0.3	-1.6	-1.2	0.2	-0.4	2.2
Medication: Paracetamol	1.4	2.3	13.2	-1.4	-1.3	-0.8	-0.9	-1.2	-0.8	-1.6	-1.2	-2.2	-1.3	0.7	-1.2	-1.4	-3.6	1.1	-1.8
Illnesses of father: Heart disease	1.4	1.9	6.6	-0.6	-1.7	-0.7	-1.3	-1.4	-0.6	-1.4	-1.5	-1.2	-1.2	1.7	-1.5	-1.7	-2.6	1.8	-0.2
Pain type(s) experienced in last month: Hip pain	1.4	1.7	3.3	-0.8	-1.4	-1.1	-1.3	-1.5	-1.1	-1.4	-1.4	-1.5	-1.8	1.1	-1.4	-1.5	-1.7	1.1	-1.1
Trunk fat percentage	1.3	5.2	9.4	-1.4	-2.7	-2.6	-2.5	-2.7	-1.6	-2.4	-2.7	-2.8	-3.1	2.3	-2.7	-2.7	-1.4	2.2	-1.0
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	4.3	-0.1	-1.3	-1.3	-1.5	-1.6	-2.1	-0.6	-1.5	-0.9	-1.0	1.6	-1.5	-1.1	-0.1	1.3	0.5
Exposure to tobacco smoke outside home	1.3	1.7	4.3	-0.0	-1.4	-1.3	-1.3	-1.3	-1.7	-1.2	-1.1	-1.7	-1.6	1.8	-1.2	-1.5	-0.5	2.1	-0.1
Irritable Bowel Disease (IBD)	1.2	2.9	10.8	-0.7	1.7	1.1	1.2	1.6	1.1	-0.1	1.5	1.2	1.3	-3.3	1.6	1.8	2.5	-3.1	1.3
Age at First Birth	1.2	1.8	4.5	0.3	-1.3	-0.7	-0.6	-1.1	-1.3	-0.8	-1.3	-1.1	-1.5	2.0	-1.3	-1.3	-2.1	2.0	-1.7
Type 2 Diabetes (T2D) (2012)	1.2	1.3	4.2	0.3	-1.1	-0.9	-1.0	-0.9	-1.1	-0.8	-0.9	-0.6	-0.7	1.8	-0.9	-1.2	-1.9	1.5	-2.1
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	3.4	0.4	-1.3	-0.7	-1.2	-1.3	-0.4	-1.1	-1.4	-1.2	-1.0	1.9	-1.4	-1.2	-1.3	1.6	-1.4
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	4.8	0.2	1.2	1.3	1.1	1.2	0.7	1.2	1.2	0.9	1.2	-1.5	1.2	1.3	2.2	-1.3	1.0
Exposure to tobacco smoke at home	1.2	1.4	2.5	1.0	1.4	1.4	1.3	1.5	0.9	0.7	1.6	1.1	1.0	-0.9	1.6	1.3	1.5	-0.8	-0.7
Body fat percentage	1.2	4.8	8.4	-1.1	-2.5	-2.2	-2.3	-2.5	-1.3	-2.2	-2.5	-2.7	-2.9	2.4	-2.5	-2.5	-1.6	2.4	-1.3
Pulse rate, automated reading	1.2	3.9	7.6	-2.2	-2.2	-2.1	-2.1	-2.2	-2.8	-2.5	-2.4	-2.3	-2.4	0.7	-2.4	-2.1	-1.1	0.5	-0.5
Qualifications: nursing, teaching	1.2	1.8	11.4	1.1	-1.0	-0.4	-0.0	-0.7	0.3	-1.1	-0.9	-0.7	-1.0	2.2	-0.9	-1.0	-1.5	2.0	-3.4
Neuroticism (Nagel 2018)	1.1	2.5	5.3	2.0	1.6	2.3	2.3	2.0	1.5	1.6	2.2	0.7	1.3	-0.4	2.2	1.7	0.7	0.4	-1.1
Ever had hysterectomy (womb removed)	1.1	1.3	3.6	-0.6	-1.2	-1.2	-1.7	-1.5	-0.6	-1.9	-1.4	-1.6	-0.7	0.7	-1.3	-1.1	-0.5	0.6	-0.5
Mouth/teeth dental problems	1.1	1.6	5.1	-2.3	-0.7	-1.3	-1.0	-1.0	-1.2	-1.6	-1.3	-0.4	-0.8	-1.3	-1.2	-0.6	-1.3	-1.8	1.7
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	3.5	1.0	1.3	1.5	1.6	1.4	0.8	1.9	1.4	1.2	1.3	-0.5	1.4	1.3	1.2	-0.5	0.4
Worry too long after embarrassment	1.1	1.8	8.6	2.9	0.7	1.0	1.2	1.0	0.8	1.5	1.1	0.1	1.2	1.8	1.0	0.7	-0.1	2.2	-2.0
Wheeze or whistling in the chest in last year	1.1	1.9	4.4	2.0	1.5	1.7	1.3	1.5	2.1	0.6	1.6	0.9	1.6	-0.2	1.6	1.4	1.3	0.2	-1.5
Arm fat percentage (left)	1.1	4.4	7.7	-0.7	-2.4	-2.1	-2.2	-2.3	-1.1	-2.0	-2.4	-2.5	-2.8	2.5	-2.4	-2.3	-1.7	2.5	-1.6
Alzheimer’s Disease (in mother)	1.0	1.2	2.8	1.6	1.3	1.7	1.3	1.4	0.8	1.1	1.4	1.1	0.5	-0.3	1.4	1.3	0.4	-0.2	-0.7
Reaction Time	1.0	1.9	5.5	-0.5	1.3	1.1	1.1	1.2	0.4	0.8	1.2	1.2	1.2	-2.3	1.2	1.4	2.2	-2.1	1.6
Ulcerative Colitis	1.0	1.5	5.2	-0.5	1.1	0.7	0.8	1.0	1.6	-0.2	0.8	0.9	1.5	-2.1	0.9	1.1	1.8	-2.3	0.4
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	2.2	1.3	1.4	1.3	1.5	1.4	0.9	0.9	1.2	1.4	0.9	-0.7	1.2	1.5	0.0	-1.1	-1.1
Leg fat percentage (right)	1.0	3.7	7.1	-0.5	-2.1	-1.8	-1.8	-1.9	-0.8	-1.8	-1.8	-2.7	-2.5	2.5	-1.9	-2.1	-1.7	2.6	-1.8
Overall health rating	1.0	2.2	4.4	1.0	1.7	0.9	1.6	1.6	1.6	0.8	1.5	1.8	1.5	-1.5	1.5	1.7	2.1	-1.7	-1.2
Leg pain on walking	1.0	1.3	2.5	-0.5	-1.3	-1.0	-1.2	-1.3	-0.4	-1.6	-1.3	-1.6	-1.1	1.1	-1.2	-1.3	-1.4	1.2	-0.5
Illnesses of siblings: Diabetes	1.0	1.2	3.0	-0.5	-1.3	-1.4	-1.7	-1.5	-0.6	-1.1	-1.5	-0.7	-0.9	1.0	-1.5	-1.2	-0.6	0.6	0.5
Number of operations (self-reported)	1.0	1.4	3.7	-1.9	-1.2	-1.3	-1.4	-1.4	-0.8	-1.4	-1.4	-1.0	-1.3	-0.1	-1.3	-1.2	-1.1	-0.2	1.4
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	4.1	-1.4	-1.0	-1.5	-1.4	-1.3	-1.1	-1.2	-1.4	-0.6	-0.7	-0.3	-1.4	-0.9	0.5	-0.4	2.0
HbA1C	0.9	1.0	3.3	0.6	1.1	1.8	0.8	0.9	-0.1	0.6	0.7	1.4	1.1	-1.4	0.7	1.3	1.1	-1.1	-0.6
Neuroticism (2016)	0.9	1.4	3.3	1.2	1.4	1.8	1.7	1.5	0.9	1.0	1.5	0.3	1.0	-0.8	1.6	1.4	0.7	-0.5	-0.5
Neuroticism	0.9	2.1	4.9	1.7	1.5	2.2	2.2	2.0	1.3	1.1	2.1	0.5	1.0	-0.8	2.1	1.6	0.7	0.1	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	2.4	-1.5	-0.9	-1.4	-1.5	-1.4	-1.3	-0.8	-1.6	-0.7	-0.6	-0.2	-1.5	-0.9	-0.4	-0.6	1.4
Fluid intelligence score	0.9	2.0	4.5	2.1	1.7	1.0	1.4	1.6	1.2	1.4	1.5	1.8	1.9	-0.5	1.5	1.8	0.5	-0.9	-1.0
Arm fat percentage (right)	0.9	3.5	6.1	-0.5	-2.1	-1.9	-1.9	-2.0	-0.9	-1.9	-2.1	-2.1	-2.5	2.2	-2.1	-2.1	-1.4	2.2	-1.7
Length of working week for main job	0.9	1.0	3.0	0.2	1.1	0.8	0.8	1.0	1.1	0.5	0.8	1.2	1.7	-1.5	0.9	1.2	0.1	-1.5	0.5
Wears glasses or contact lenses	0.9	1.0	2.1	-0.3	-1.2	-0.9	-1.2	-1.1	-0.3	-0.9	-0.9	-1.1	-1.1	1.3	-1.0	-1.2	-1.5	1.4	0.4
Hearing aid user	0.9	1.0	5.0	0.7	-0.8	-0.0	-0.1	-0.4	-0.0	-0.1	-0.5	-1.1	-0.8	1.8	-0.5	-0.7	-1.3	1.9	-2.2
Medication: Paracetamol	0.9	1.4	9.9	-0.8	-0.8	-0.4	-0.4	-0.5	-0.0	-1.4	-0.5	-1.5	-1.0	0.5	-0.5	-1.0	-3.1	1.0	-2.0
Illnesses of father: High blood pressure	0.9	1.1	2.2	0.9	1.1	1.1	1.3	1.3	1.5	0.4	1.2	1.1	0.8	-0.8	1.2	1.1	-0.3	-0.8	-1.4
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.5	-0.7	-1.3	-1.2	-1.0	-1.2	-1.1	-1.6	-1.3	-0.8	-1.3	0.9	-1.3	-1.4	-1.3	0.8	-0.5
High blood pressure (mother)	0.8	1.1	2.2	-0.7	-1.2	-1.3	-1.5	-1.3	-1.5	-0.5	-1.2	-1.0	-0.7	1.1	-1.3	-1.2	-0.9	1.0	0.5
Trunk fat mass	0.8	3.4	5.4	-0.8	-2.1	-2.1	-2.1	-2.2	-1.1	-2.0	-2.3	-2.0	-2.3	2.0	-2.2	-2.1	-1.2	1.9	-0.9
Had menopause	0.8	1.1	2.3	-1.0	-1.3	-0.8	-1.1	-1.1	-1.0	-1.1	-0.9	-1.5	-1.5	0.9	-0.9	-1.3	-0.3	1.2	-0.2
Number of live births	0.8	1.1	4.7	-1.9	-0.2	-1.1	-0.8	-0.5	-0.8	-0.8	-0.4	-0.6	-0.5	-1.5	-0.4	-0.2	1.4	-1.6	2.2
Qualifications: A levels/AS levels or equivalent	0.8	1.8	4.9	2.0	1.4	0.8	1.2	1.2	1.1	2.2	1.1	2.2	2.1	0.0	1.1	1.6	0.9	-0.7	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	4.9	1.1	1.4	1.0	1.6	1.4	0.9	1.5	1.2	2.2	1.9	-0.8	1.2	1.4	1.0	-1.3	-0.4
Friendships satisfaction	0.8	1.0	3.5	0.7	1.0	1.1	1.4	1.2	0.3	1.0	1.1	0.7	0.9	-0.6	1.1	1.1	1.9	-0.6	-0.5
Ever taken oral contraceptive pill	0.8	0.9	4.1	-0.9	0.8	0.1	0.6	0.7	0.2	0.3	0.6	1.0	0.7	-1.9	0.6	0.8	0.8	-2.0	1.1
Fasting Glucose	0.7	0.8	2.6	-0.9	-1.0	-0.6	-1.6	-1.3	-0.5	-1.4	-1.4	-0.3	-0.4	-0.3	-1.3	-0.6	0.2	-0.1	0.8
Hearing difficulty/problems: Yes	0.7	1.0	5.7	1.9	-0.0	0.6	0.4	0.0	0.5	0.6	0.0	-0.3	0.0	1.8	-0.0	-0.0	-0.7	1.7	-2.4
Relative age of first facial hair	0.7	1.4	9.5	1.5	-0.4	0.1	0.7	0.2	0.8	-0.3	0.1	-0.2	-0.6	1.9	0.1	-0.5	-1.0	2.2	-3.1
Medication for hormone replacement therapy	0.7	0.8	2.2	-1.4	-0.9	-0.8	-1.2	-1.0	-0.7	-0.9	-1.0	-1.5	-0.7	-0.2	-1.0	-1.0	-0.0	0.0	0.5
Vitamin and mineral supplements	0.7	0.9	2.6	0.1	-1.1	-1.6	-0.7	-1.0	-0.9	-0.7	-1.1	-0.4	-0.7	1.5	-1.1	-1.2	-0.6	1.3	-0.6
Medication: Co-codamol	0.7	0.8	3.0	0.1	-0.9	-0.2	-0.2	-0.5	-0.8	0.1	-0.4	-0.6	-1.4	1.6	-0.5	-0.9	-1.3	1.7	-0.6
High blood pressure	0.7	1.9	5.0	1.5	1.3	1.5	1.6	1.5	2.2	1.7	1.5	0.6	1.5	-0.1	1.5	1.3	0.8	0.2	-1.9
Body mass index (BMI)	0.7	2.9	4.8	-0.1	-1.8	-1.5	-1.7	-1.8	-0.5	-1.9	-1.8	-2.2	-1.9	2.2	-1.8	-1.8	-1.7	2.2	-1.9
Heart attack	0.7	1.0	2.2	-0.7	-1.2	-1.0	-0.8	-1.0	-0.8	-1.5	-1.1	-0.6	-1.2	0.7	-1.1	-1.2	-1.4	0.6	-0.6
Illnesses of siblings	0.7	1.0	2.0	0.9	1.2	0.7	1.4	1.4	0.3	0.8	1.2	1.4	1.2	-0.8	1.2	1.2	0.5	-1.0	-0.4
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.2	0.3	1.3	1.5	1.3	1.3	1.4	0.8	1.4	0.7	1.3	-1.4	1.5	1.3	0.8	-1.3	0.3
Medication for pain relief, constipation, heartburn	0.7	1.2	5.3	0.2	0.9	0.6	0.6	0.8	0.9	0.5	0.9	1.2	1.6	-1.3	0.9	1.0	2.3	-1.3	1.1
Medication: Ibuprofen	0.7	0.8	1.7	1.1	1.0	1.0	1.3	1.2	0.7	0.9	1.0	1.1	0.6	-0.3	1.0	1.1	0.1	-0.6	-1.1
Whole body fat mass	0.7	2.7	4.3	-0.5	-1.9	-1.7	-1.8	-1.9	-0.7	-1.7	-1.9	-2.0	-2.1	2.0	-1.9	-1.8	-1.4	1.9	-1.1
Leg fat mass (right)	0.7	2.6	4.4	-0.3	-1.8	-1.5	-1.6	-1.7	-0.7	-1.8	-1.7	-2.1	-1.9	2.0	-1.7	-1.7	-1.4	2.0	-1.2
Suffer from ‘nerves’	0.7	1.1	4.4	0.5	1.1	0.4	1.1	1.1	0.5	1.2	1.1	1.5	0.9	-0.8	1.1	1.1	2.1	-0.9	0.5
Medication: Aspirin	0.7	1.0	2.2	-0.2	-1.2	-0.9	-1.1	-1.1	-0.7	-0.3	-1.1	-0.8	-1.2	1.5	-1.2	-1.2	-0.9	1.3	0.3
Medication: Gliclazide	0.7	0.8	2.0	-0.7	-1.0	-0.3	-0.7	-0.8	-1.2	-0.5	-0.8	-1.4	-1.4	0.7	-0.8	-1.0	-0.4	1.1	0.8
Eye problems/disorders: Glaucoma	0.7	0.8	2.9	0.4	0.9	1.0	0.8	0.8	1.7	0.0	0.7	1.2	1.0	-1.1	0.8	0.9	0.3	-1.3	-0.6
Alcohol drinker status: Previous	0.7	0.8	2.2	0.8	-0.8	-1.0	-0.8	-0.8	0.2	-0.9	-0.9	-0.4	-0.6	1.5	-0.9	-0.8	-1.2	1.2	-1.5
Type 2 Diabetes (T2D) (2018)	0.6	1.1	4.1	2.0	1.0	1.6	1.3	1.0	1.0	1.6	1.0	0.9	0.4	0.6	0.9	0.8	0.3	0.7	-0.3
Frequency of depressed mood in last 2 weeks	0.6	0.8	3.1	-0.4	0.8	0.8	0.6	0.6	0.4	0.9	0.6	0.9	0.5	-1.2	0.5	0.8	1.3	-1.3	1.8
Relative age voice broke	0.6	1.0	4.6	1.4	0.5	0.9	1.1	0.9	1.2	0.5	0.8	0.9	0.5	0.6	0.8	0.5	-1.3	0.6	-2.1
Hayfever, allergic rhinitis or eczema	0.6	1.2	3.0	1.6	1.0	1.7	1.2	1.3	1.1	1.7	1.3	1.1	1.1	0.3	1.2	1.0	0.2	0.5	0.5
Medication: Levothyroxine sodium	0.6	1.1	3.7	-0.2	1.1	0.9	1.1	1.0	1.3	0.4	1.0	0.9	1.3	-1.7	1.0	1.2	0.4	-1.9	0.2
Alcohol usually taken with meals	0.6	0.9	2.3	0.3	1.1	1.1	0.6	0.7	1.2	1.4	0.9	0.5	1.5	-1.2	0.8	1.2	-0.1	-1.0	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	2.2	0.8	0.9	1.0	1.4	1.1	1.5	1.3	0.9	0.9	0.6	-0.2	0.9	0.9	-0.9	-0.2	-1.3
Lung cancer (father)	0.6	0.7	2.6	-1.4	-0.3	-0.2	-0.8	-0.6	-1.6	-0.5	-0.4	-1.2	-1.0	-0.8	-0.4	-0.3	1.1	-0.4	0.7
Pulse wave Arterial Stiffness index	0.6	0.7	2.6	0.2	0.9	0.7	0.9	0.9	0.2	1.2	0.8	0.5	0.8	-0.8	0.8	0.9	1.6	-0.6	0.8
Knee pain experienced in last month	0.6	0.9	5.4	0.0	-0.9	0.0	-0.7	-0.8	-0.3	-0.8	-0.7	-1.3	-0.8	1.2	-0.7	-0.8	-2.3	1.4	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	4.5	2.1	0.4	0.6	0.3	0.3	1.3	1.0	0.4	0.7	0.9	1.3	0.3	0.4	0.7	1.1	-2.0
Breast cancer (self-reported)	0.6	0.7	1.6	0.3	-0.8	-1.1	-1.3	-1.0	-0.6	-0.5	-1.0	-0.9	-0.3	1.3	-1.0	-0.8	-0.6	1.1	0.1
Smoking status: Current	0.6	1.0	3.5	0.2	1.1	0.6	0.6	0.8	0.9	0.4	0.7	0.9	1.1	-1.6	0.8	1.1	1.9	-1.7	0.5
Schizophrenia vs Biploar Disorder	0.5	0.7	2.8	-0.3	0.8	0.4	0.4	0.4	0.8	0.2	0.5	1.0	0.6	-1.4	0.5	0.8	1.5	-1.7	0.7
Body Mass Index (BMI) (2010)	0.5	0.6	1.3	1.0	1.0	0.9	0.6	0.9	0.8	0.8	1.0	1.0	0.7	-0.4	1.1	1.1	0.2	-0.5	-0.5
Blood Red Count	0.5	5.3	10.2	1.2	2.8	1.6	2.2	2.3	2.3	2.2	2.2	2.9	2.8	-2.5	2.2	2.8	2.8	-3.2	0.6
BMI	0.5	2.9	6.4	-0.9	-1.8	-1.6	-1.7	-1.9	-0.9	-2.2	-1.8	-2.5	-2.4	1.5	-1.8	-1.8	-1.5	1.7	-1.1
Waist Hip Ratio (WHR)	0.5	2.3	6.3	0.8	1.7	1.7	1.6	1.7	2.5	1.0	1.6	1.4	2.0	-1.6	1.7	1.6	-0.6	-1.3	-1.1
Hypothyroidism (self reported)	0.5	1.2	1.9	0.3	1.1	1.4	1.3	1.3	1.3	1.3	1.3	1.1	1.2	-1.0	1.3	1.2	0.3	-1.1	0.1
Chronotype (morning person)	0.5	1.1	3.3	-0.5	-1.0	-0.5	-0.5	-0.7	-0.1	-1.4	-0.8	-1.3	-1.4	0.9	-0.8	-1.2	-1.6	1.0	-1.8
Tanning	0.5	6.0	12.1	0.7	2.9	2.8	2.3	2.7	2.5	1.7	2.6	2.5	2.4	-3.5	2.7	2.9	1.6	-3.2	2.0
Supplements: Zinc	0.5	0.6	2.5	0.2	0.7	1.6	1.0	1.0	0.6	1.0	1.1	0.1	0.3	-0.3	1.1	0.7	0.2	0.1	0.0
Current tobacco smoking	0.5	0.7	3.0	0.1	1.0	0.5	0.5	0.7	0.6	0.3	0.6	0.6	0.8	-1.5	0.6	0.9	1.7	-1.5	0.6
Average weekly fortified wine intake	0.5	0.6	2.1	-0.2	-0.7	-0.4	-0.3	-0.6	-1.1	-1.3	-0.5	-1.5	-1.3	0.6	-0.4	-0.8	-0.2	0.9	-0.9
Prospective memory result	0.5	0.6	3.6	-1.9	-0.6	-0.4	-0.5	-0.6	-0.3	-0.5	-0.6	-0.8	-0.7	-0.8	-0.6	-0.6	0.1	-0.4	1.2
Arm fat mass (right)	0.5	2.2	3.4	-0.3	-1.6	-1.6	-1.6	-1.7	-0.6	-1.7	-1.8	-1.7	-1.9	1.8	-1.8	-1.6	-1.1	1.7	-1.2
Glaucoma (self-reported)	0.5	0.6	1.6	0.5	0.9	0.9	0.9	0.8	1.0	0.6	0.7	1.3	0.7	-0.8	0.8	0.9	0.4	-1.0	-0.6
High blood pressure (siblings)	0.5	0.8	2.3	-0.2	-0.9	0.1	-0.8	-0.7	0.2	-1.0	-0.6	-1.5	-0.9	0.9	-0.6	-0.8	-1.5	1.4	-0.7
Number of full brothers	0.5	0.6	1.4	-0.8	-0.8	-1.2	-1.2	-0.9	-0.1	-1.1	-0.9	-0.6	-0.5	-0.0	-0.9	-0.8	-0.3	0.1	1.1
Pulse wave peak to peak time	0.5	0.5	2.0	-0.2	-0.8	-0.7	-0.9	-0.8	-0.3	-1.1	-0.8	-0.3	-0.7	0.6	-0.8	-0.8	-1.4	0.4	-0.6
Medication: Seretide 50 evohaler	0.5	0.6	2.3	-1.5	-0.6	-1.0	-0.7	-0.6	-1.1	-0.9	-0.7	-0.2	-0.8	-0.5	-0.6	-0.7	-0.8	-0.6	0.4
Alcohol intake frequency.	0.5	1.2	4.5	2.1	0.7	0.7	0.8	0.7	2.0	1.2	0.7	0.5	0.7	1.1	0.7	0.6	0.7	1.0	-1.7
Had major operations	0.5	0.6	1.7	-1.3	-0.6	-0.8	-1.1	-0.8	-0.3	-1.3	-0.7	-0.8	-0.5	-0.7	-0.7	-0.5	-0.1	-0.5	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	3.8	0.2	-0.6	-0.0	-0.2	-0.2	-0.6	-0.2	-0.2	-0.5	-0.7	1.1	-0.3	-0.7	-1.9	1.4	-0.5
Diabetes diagnosed by doctor	0.5	0.8	2.2	1.4	0.9	1.5	0.8	0.8	0.6	1.3	0.9	1.0	0.4	-0.2	0.8	0.9	0.8	-0.1	1.2
Illnesses of father: None of the above (group 1)	0.5	0.6	2.3	-1.1	-0.5	-0.9	-1.1	-0.8	-1.0	-0.1	-0.6	-1.1	-0.5	-0.3	-0.7	-0.4	0.4	-0.1	1.5
Arm fat mass (left)	0.5	2.2	3.7	-0.1	-1.6	-1.5	-1.6	-1.7	-0.4	-1.7	-1.7	-1.7	-1.8	1.9	-1.7	-1.6	-1.2	1.9	-1.3
Guilty feelings	0.5	0.8	1.6	1.2	1.0	1.1	1.3	1.0	0.8	0.8	1.0	0.3	0.6	-0.4	1.0	1.1	1.0	-0.3	-0.9
Medication: Bendroflumethiazide	0.5	0.8	2.8	0.9	0.6	1.7	1.0	0.9	1.4	0.9	0.9	-0.1	0.6	0.2	0.9	0.7	-0.7	0.6	-1.5
Alcohol drinker status: Never	0.5	0.6	2.8	0.6	-0.7	-0.4	-0.8	-0.7	-0.2	-0.2	-0.5	-0.9	-0.2	1.6	-0.6	-0.8	0.1	1.7	0.1
Leg fat percentage (left)	0.5	1.7	4.3	0.1	-1.3	-1.1	-1.0	-1.2	-0.2	-0.9	-1.1	-1.7	-1.7	2.0	-1.1	-1.2	-0.9	2.1	-2.0
Depressed Affect (Nagel 2018)	0.4	0.9	3.3	1.1	0.7	1.8	1.4	1.1	0.7	0.8	1.3	-0.4	-0.0	0.1	1.2	0.7	-0.4	1.0	-0.6
Depression (Nagel 2018)	0.4	0.5	1.8	-1.3	-0.8	-0.2	-0.7	-0.8	-0.7	-0.9	-0.9	-0.4	-0.7	-0.4	-0.9	-0.5	-0.7	-0.5	0.8
Hand grip strength (left)	0.4	1.1	2.6	0.4	-1.1	-0.6	-0.6	-1.0	-1.0	-1.5	-1.0	-0.7	-1.2	1.5	-1.0	-1.1	-1.2	1.4	-1.6
Number of treatments/medications taken	0.4	0.6	1.4	-0.8	-0.9	-0.3	-0.7	-0.8	-0.8	-0.6	-0.7	-1.1	-1.0	0.7	-0.8	-0.9	-1.2	0.8	-0.3
Diabetes (father)	0.4	0.5	1.9	0.2	0.7	1.4	0.7	0.7	0.9	0.4	0.7	0.5	0.7	-0.9	0.7	0.8	0.6	-0.8	-0.1
Multivitamins +/- minerals	0.4	0.5	1.9	-1.4	-0.1	0.6	-0.5	-0.2	-0.6	-0.4	-0.1	-0.7	-0.6	-1.1	-0.1	0.1	-0.7	-0.9	1.3
Stomach or abdominal pain in last month	0.4	0.5	1.9	-0.6	-0.6	-0.6	-1.0	-0.9	0.1	-0.5	-0.8	-0.5	-0.2	0.1	-0.8	-0.6	-1.1	0.1	1.4
Nervous feelings	0.4	0.7	2.5	1.6	0.6	0.5	1.2	0.8	0.3	1.2	0.8	0.6	0.7	0.8	0.8	0.6	0.3	1.0	-0.6
Mouth/teeth dental problems: Dentures	0.4	0.6	2.7	0.0	-0.7	0.2	-0.2	-0.1	-0.4	-0.8	-0.0	-1.4	-1.2	1.0	-0.0	-0.8	-0.4	1.6	-1.1
Peak expiratory flow (PEF)	0.4	1.0	2.6	0.6	-0.9	-1.1	-0.9	-1.1	-0.4	-0.8	-1.4	-0.5	-0.3	1.6	-1.4	-0.9	-1.1	0.9	-1.2
Loud music exposure frequency	0.4	0.4	1.4	-0.2	-0.6	-0.7	-0.8	-0.7	-1.2	0.0	-0.6	-0.5	-0.5	0.7	-0.6	-0.6	0.1	0.7	1.0
Headache pain in last month	0.4	0.8	2.2	0.9	1.0	0.8	0.7	0.8	1.5	1.2	0.9	0.9	1.3	-0.6	0.9	1.0	-0.2	-0.4	0.8
Age at first live birth	0.4	0.7	1.6	0.7	0.7	1.2	1.3	1.0	0.4	1.2	0.9	1.0	0.6	-0.1	0.8	0.8	-1.1	-0.1	-0.6
Shortness of breath walking on level ground	0.4	0.5	1.3	-0.2	-0.8	-0.1	-0.7	-0.8	0.2	-1.2	-0.8	-1.0	-0.5	0.5	-0.7	-0.8	-0.9	0.6	0.1
Mouth/teeth dental problems: Loose teeth	0.4	0.5	2.2	1.0	0.7	0.4	0.3	0.6	0.8	-0.3	0.6	0.8	0.4	-0.6	0.7	0.8	1.5	-0.6	0.9
Neck or shoulder pain in last month	0.4	0.6	1.3	1.0	0.9	0.4	0.5	0.7	0.8	1.0	0.8	1.1	0.6	-0.2	0.8	0.9	1.2	-0.3	-0.2
Medication: Allopurinol	0.4	0.5	0.9	-0.6	-0.9	-1.0	-0.7	-0.6	-0.7	-0.6	-0.6	-0.8	-0.8	0.8	-0.7	-0.9	-0.3	0.8	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.8	1.0	0.1	0.8	0.5	0.3	0.6	0.4	0.4	-0.8	0.3	0.8	0.4	0.0	-0.8	1.3	-1.3
Hypertension (Self-reported)	0.4	1.2	4.0	1.3	0.8	1.2	1.1	1.0	2.0	1.4	1.1	0.1	1.1	0.5	1.0	0.8	0.1	0.7	-2.0
Eye problems/disorders: Cataract	0.4	0.5	1.1	0.8	0.7	0.6	0.4	0.6	1.0	0.7	0.6	0.9	0.9	-0.4	0.6	0.8	0.7	-0.4	1.1
Medication: Aspirin	0.4	0.6	1.0	-0.6	-0.9	-0.8	-1.0	-0.9	-0.8	-0.2	-0.9	-0.6	-0.9	0.7	-1.0	-0.9	-0.2	0.5	1.0
Commuting to job workplace: Public transport	0.4	0.4	1.6	0.4	0.8	0.2	0.7	0.6	-0.2	1.3	0.7	0.9	0.6	-0.6	0.7	0.9	0.4	-0.6	0.4
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.2	-0.7	-0.7	-0.3	-0.6	-0.5	-0.5	-1.0	-0.4	-1.2	-0.9	0.4	-0.4	-0.7	-1.5	0.6	-0.9
Irritability	0.4	0.6	2.9	-1.1	-0.3	0.7	-0.4	-0.4	-1.3	-0.6	-0.2	-1.7	-0.8	-0.6	-0.2	-0.3	-0.8	0.2	1.2
Myopia	0.4	0.6	1.5	0.5	0.9	0.4	0.5	0.5	0.4	0.4	0.5	0.8	1.2	-0.9	0.6	0.9	1.2	-1.1	0.8
Alzheimer’s Disease (in father)	0.3	0.3	1.1	0.7	0.2	-0.1	-0.1	-0.1	0.7	0.6	0.0	1.0	0.9	0.5	0.0	0.2	-1.0	0.1	-0.7
Verbal and Numeric Reasoning (VNR)	0.3	0.8	2.7	1.0	0.9	0.4	1.1	1.1	0.9	0.4	1.0	1.0	1.2	-0.5	1.0	1.0	-0.2	-0.7	-1.6
Coronary Artery Disease (CAD)	0.3	0.4	1.1	-0.2	-0.3	-1.1	-0.8	-0.9	-0.9	-0.7	-0.8	-0.8	0.2	0.2	-0.8	-0.4	-0.3	-0.2	-0.9
Crohns Disease (2012)	0.3	0.5	1.5	-0.9	-0.5	-0.9	-0.8	-0.6	-0.6	-1.2	-0.6	-0.5	-0.4	-0.5	-0.6	-0.4	0.9	-0.5	0.5
HDL Cholesterol	0.3	0.5	1.3	-1.1	-0.7	-0.9	-0.6	-0.7	-0.3	-1.1	-0.8	-0.7	-0.2	-0.1	-0.8	-0.6	-0.9	-0.4	-0.0
Primary Biliary Cirrhosis	0.3	0.5	3.9	-0.4	-0.6	-0.0	-0.6	-0.4	-0.6	-0.3	-0.3	-0.6	-0.5	0.5	-0.4	-0.6	-2.0	0.8	0.2
Rheumatoid Arthritis	0.3	0.5	1.6	-0.9	-0.6	-0.6	-0.8	-0.7	-0.2	-1.2	-0.7	-0.5	-0.4	-0.3	-0.7	-0.6	-1.0	-0.4	0.8
Triglycerides	0.3	0.5	1.6	-0.4	-0.6	-1.2	-0.6	-0.6	-1.3	-0.6	-0.5	-0.2	-0.7	0.1	-0.5	-0.6	1.1	0.2	0.8
Blood Eosinophil Count	0.3	2.1	5.5	0.9	1.7	1.7	1.3	1.3	1.4	1.1	1.2	2.4	1.4	-1.4	1.2	1.6	1.8	-1.8	1.1
Sensitivity / hurt feelings	0.3	0.4	1.3	0.6	0.6	1.0	1.0	0.8	0.6	0.2	0.9	-0.3	0.2	-0.1	0.9	0.5	0.0	0.5	-1.1
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.9	-0.3	-0.5	-0.1	-0.4	-0.4	0.3	-1.3	-0.3	-0.7	-0.8	0.3	-0.3	-0.6	-1.1	0.5	-1.4
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.9	-0.1	-0.7	-0.6	-0.5	-0.5	-0.1	-0.7	-0.5	-1.4	-0.6	0.8	-0.5	-0.8	0.5	1.2	0.3
Medication: Atenolol	0.3	0.4	1.6	0.3	-0.4	-0.1	0.2	-0.2	-0.4	0.6	-0.1	-0.4	-0.7	1.2	-0.1	-0.5	-0.8	1.2	-1.0
Medication: Ramipril	0.3	0.4	1.6	0.7	-0.2	-0.1	0.1	-0.1	-0.3	0.4	-0.0	-0.4	-0.4	1.1	-0.1	-0.3	1.3	1.1	-1.0
Time employed in main current job	0.3	0.4	0.9	-0.7	-0.7	-0.9	-0.7	-0.8	-0.2	-0.9	-0.9	-0.3	-0.1	0.4	-0.9	-0.6	-0.3	-0.2	-0.7
Falls in the last year	0.3	0.4	1.7	1.3	0.4	0.7	0.4	0.4	0.3	0.7	0.6	-0.2	0.2	0.6	0.6	0.5	-0.3	0.9	-0.9
Medication: Lansoprazole	0.3	0.3	1.8	-0.6	-0.1	0.3	-0.1	0.2	0.0	-1.0	0.1	-0.9	-0.4	-0.4	0.2	-0.2	-1.4	0.0	-1.1
Illnesses of mother	0.3	0.4	1.4	-0.2	0.6	0.5	0.6	0.5	0.8	-0.2	0.6	0.3	0.9	-1.2	0.6	0.6	0.9	-0.9	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	3.2	1.0	1.2	0.7	0.8	0.8	0.8	1.0	0.7	1.5	1.8	-0.7	0.7	1.2	0.7	-1.2	0.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.2	-1.0	-0.6	-1.1	-0.8	-0.7	-0.7	-1.0	-0.8	-0.5	-0.5	-0.3	-0.8	-0.5	-0.1	-0.5	0.6
Gout (self-reported)	0.3	0.4	1.4	-1.1	-0.8	-0.5	-0.8	-0.6	-0.2	-0.7	-0.6	-0.6	-0.6	-0.1	-0.6	-0.7	0.0	0.1	1.2
Medication: Amlodipine	0.3	0.4	4.2	-0.4	-0.5	-0.2	0.1	-0.2	-0.1	-0.6	-0.3	-0.8	-0.8	0.3	-0.3	-0.5	-0.3	0.5	-2.0
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.4	1.2	0.2	-0.6	0.5	0.4	0.0	0.7	0.4	0.3	0.3	1.1	0.3	0.1	1.0	0.8	-1.0
Comparative body size at age 10	0.3	0.8	3.7	1.1	1.0	0.7	0.9	0.8	1.0	0.6	0.8	0.8	0.4	-0.5	0.8	1.0	1.1	-0.5	-1.9
Emphysema/chronic bronchitis	0.3	0.4	2.4	-0.9	-0.2	-1.0	-0.6	-0.3	-0.7	-0.0	-0.4	-0.4	-0.1	-0.5	-0.4	-0.1	0.4	-0.5	1.6
Medication: Blood pressure	0.3	0.5	1.0	0.8	0.4	1.0	0.8	0.7	1.0	0.7	0.8	0.1	0.4	0.2	0.8	0.4	-0.4	0.7	-1.0
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.6	0.9	0.7	1.2	0.4	0.6	0.9	0.9	0.6	0.0	0.4	0.1	0.6	0.6	0.4	0.1	-0.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.2	1.1	0.3	0.4	0.6	0.4	0.7	0.6	0.4	0.3	0.6	0.7	0.4	0.2	-1.0	0.7	-1.1
Ever had bowel cancer screening	0.3	0.3	1.6	0.3	-0.4	-0.3	-0.2	-0.3	0.2	-0.2	-0.4	-0.4	-0.1	1.0	-0.4	-0.4	-1.3	0.9	-0.7
Commuting to job workplace: Walk	0.3	0.4	1.7	0.4	-0.5	-0.7	-0.2	-0.2	0.3	-0.9	-0.3	-0.1	0.1	0.8	-0.2	-0.6	-1.3	0.8	-1.0
Medication for cholesterol	0.3	0.5	2.0	0.6	0.8	0.4	0.7	0.7	-0.1	0.1	0.6	1.4	0.4	-0.7	0.7	0.8	0.3	-0.9	1.4
Osteoarthritis (self-reported)	0.3	0.4	1.6	0.6	0.4	0.6	0.5	0.6	0.9	-0.7	0.6	-0.3	-0.0	-0.2	0.7	0.4	-0.6	0.2	-1.3
Mother’s age at death	0.3	0.4	1.9	0.0	-0.5	0.2	-0.9	-0.6	-0.9	-0.7	-0.4	-0.6	-0.4	0.6	-0.4	-0.5	-0.5	0.6	1.4
Medication: Blood pressure	0.3	0.6	4.4	0.6	0.4	0.8	0.8	0.6	1.1	1.0	0.6	0.0	0.7	0.4	0.5	0.3	0.1	0.4	-2.1
Average weekly beer plus cider intake	0.3	0.4	2.1	0.8	-0.5	-0.2	-0.2	-0.4	-0.4	0.2	-0.4	-0.3	-0.6	1.4	-0.4	-0.6	-0.0	1.5	-0.9
Vascular/heart problems diagnosed by doctor	0.3	0.9	3.9	-1.0	-0.7	-0.9	-1.1	-0.9	-1.5	-1.1	-0.9	-0.1	-0.8	-0.3	-0.9	-0.7	-0.3	-0.5	2.0
Pain experienced in last month	0.3	0.5	1.8	-1.3	-0.4	-0.5	-0.5	-0.5	-0.8	-0.7	-0.6	-0.1	-0.4	-0.9	-0.6	-0.3	1.0	-1.1	0.8
Pack years of smoking	0.3	0.5	1.2	-1.0	-0.5	-0.7	-0.7	-0.6	-0.9	-0.8	-0.4	-0.7	-0.9	-0.4	-0.4	-0.5	0.7	-0.2	1.1
Leg fat mass (left)	0.3	1.3	2.4	0.0	-1.2	-1.1	-1.1	-1.2	-0.3	-1.2	-1.2	-1.4	-1.4	1.5	-1.2	-1.1	-0.9	1.5	-1.2
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.4	-0.2	-0.8	-1.2	-0.7	-0.6	-1.0	-0.8	-0.7	-0.5	-0.9	0.7	-0.6	-0.7	-0.6	0.4	-1.0
Crohns Disease (2017)	0.2	0.4	2.1	-0.5	0.5	-0.0	0.0	0.3	0.0	-0.7	0.2	0.3	-0.0	-1.4	0.3	0.5	1.2	-1.5	0.4
Breast Cancer	0.2	0.4	0.6	-0.4	-0.7	-0.7	-0.6	-0.7	-0.3	-0.5	-0.7	-0.5	-0.8	0.8	-0.7	-0.7	-0.8	0.8	-0.0
Prostate Cancer	0.2	0.2	0.9	0.9	-0.1	-0.6	-0.3	-0.3	-0.2	0.0	-0.3	0.3	0.0	0.7	-0.3	-0.1	0.8	0.4	-1.0
Allergy or Eczema	0.2	0.6	2.4	0.8	0.6	1.5	0.7	0.8	0.3	1.5	0.9	0.4	0.6	0.3	0.8	0.5	-0.5	0.7	0.8
Cardiovascular Disease	0.2	0.8	5.1	1.5	0.3	0.0	0.2	0.1	0.9	1.1	0.2	0.1	0.5	1.4	0.1	0.1	0.3	1.1	-2.3
Diabetes (mother)	0.2	0.3	2.3	-0.9	-0.3	-0.2	-0.6	-0.4	-0.4	0.1	-0.4	-0.4	-0.1	-0.5	-0.4	-0.1	-0.1	-0.4	1.5
Pack years adult smoking proportion	0.2	0.3	1.1	-0.6	0.2	0.1	0.1	0.2	-0.3	-0.4	0.3	0.0	-0.2	-1.0	0.3	0.2	1.1	-0.8	0.8
Fed-up feelings	0.2	0.4	1.4	0.3	0.1	1.2	0.6	0.3	-0.4	0.7	0.4	-1.0	-0.5	0.5	0.4	0.0	-1.0	1.2	0.2
Age when periods started (menarche)	0.2	0.4	1.6	1.3	0.2	0.2	0.3	0.3	0.8	0.5	0.2	0.7	0.5	1.0	0.2	0.1	-0.2	0.8	-1.1
Sitting height	0.2	1.4	4.6	0.8	1.1	0.0	0.8	0.8	0.7	0.9	0.6	2.1	1.9	-0.9	0.6	1.1	2.0	-1.7	1.5
Hair/balding pattern: Pattern 2	0.2	0.3	1.3	-1.1	-0.4	-0.8	-0.6	-0.4	-0.3	-0.6	-0.6	-0.2	-0.1	-0.4	-0.5	-0.4	-0.4	-0.6	0.5
Allergy	0.2	0.5	1.4	-0.6	-0.7	-0.8	-0.6	-0.8	-0.7	-0.9	-0.7	-0.9	-0.8	0.4	-0.7	-0.8	0.2	0.3	-1.2
Diabetes (self-reported)	0.2	0.3	1.1	0.9	0.3	1.1	0.5	0.4	0.2	0.6	0.5	0.1	-0.1	0.2	0.5	0.3	0.2	0.6	0.9
Neuroticism score	0.2	0.5	2.0	0.2	0.7	1.4	1.1	0.9	-0.2	0.4	1.0	-0.4	0.1	-0.7	1.0	0.6	-0.0	0.2	0.3
Weight	0.2	0.9	2.2	0.5	-0.9	-1.0	-0.9	-1.0	-0.0	-1.1	-1.2	-0.8	-0.8	1.5	-1.1	-0.9	-0.6	1.2	-1.0
Hip circumference	0.2	0.8	3.7	1.3	-0.6	-0.4	-0.5	-0.7	0.1	-0.3	-0.7	-0.5	-0.7	1.9	-0.7	-0.5	-0.2	1.7	-1.1
Pulse rate	0.2	0.3	1.4	-0.2	-0.4	-0.6	-0.6	-0.6	-1.2	-0.6	-0.7	-0.5	-0.4	0.2	-0.7	-0.4	0.2	-0.2	-0.6
Medication: Cholesterol lowering	0.2	0.3	1.0	0.9	0.4	0.8	0.8	0.5	0.1	1.0	0.6	0.6	0.0	0.4	0.5	0.4	0.1	0.4	-0.2
Standing height	0.2	2.3	6.9	0.9	1.6	0.8	1.3	1.2	0.7	1.3	1.0	2.6	2.2	-1.4	1.0	1.6	2.2	-2.2	1.8
Tense / ‘highly strung’	0.2	0.3	0.7	-0.4	0.4	0.1	0.4	0.4	-0.6	0.5	0.4	0.7	0.0	-0.8	0.4	0.4	0.2	-0.7	0.8
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.0	-0.5	-0.6	-1.0	-0.5	-0.5	-0.6	-1.0	-0.5	0.1	-0.7	0.2	-0.5	-0.6	-0.7	0.2	0.5
Forced vital capacity (FVC), Best measure	0.2	0.8	2.9	0.4	0.9	0.3	0.5	0.5	0.1	0.4	0.3	1.6	1.2	-1.1	0.3	0.9	1.2	-1.7	1.0
Number of children fathered	0.2	0.2	0.9	0.1	-0.0	0.8	0.2	0.2	0.8	-0.4	0.3	-0.4	-0.3	0.0	0.3	-0.1	-0.9	0.6	-0.6
Eye problems/disorders: None of the above	0.2	0.2	1.7	-0.3	-0.2	-0.3	0.3	-0.0	-0.8	-0.4	-0.1	-0.8	-0.4	0.2	-0.1	-0.3	-0.5	0.3	-1.3
Migraine (self-reported)	0.2	0.2	1.0	-0.4	0.1	-0.0	-0.5	-0.3	-0.2	-0.7	-0.2	-0.5	0.3	-0.9	-0.1	0.1	-0.6	-0.7	1.0
Mean time to correctly identify matches	0.2	0.3	1.8	-0.9	0.2	0.5	0.2	0.2	-0.2	0.1	0.2	0.1	0.3	-1.0	0.2	0.3	0.9	-0.7	1.3
Heart disease (mother)	0.2	0.2	1.0	-0.1	0.4	0.3	0.6	0.5	0.2	0.2	0.3	0.4	0.3	-0.7	0.3	0.4	0.0	-1.0	0.1
Mood swings	0.2	0.3	1.4	0.0	-0.2	0.6	0.3	0.0	-1.2	0.2	0.1	-0.7	-1.0	0.4	0.0	-0.2	-0.9	0.9	0.2
Loneliness, isolation	0.2	0.3	1.7	-0.3	0.4	0.5	0.4	0.4	0.4	0.2	0.4	-0.1	0.1	-1.0	0.4	0.5	1.0	-0.7	1.3
Back pain experienced in last month	0.2	0.4	1.3	0.5	0.7	0.0	0.6	0.6	0.2	0.8	0.8	0.7	0.4	-0.2	0.8	0.6	0.5	-0.2	1.1
Average weekly champagne plus white wine intake	0.2	0.3	0.8	-0.2	-0.5	-0.3	-0.5	-0.5	-0.8	-0.1	-0.6	-0.3	-0.3	0.9	-0.6	-0.5	-0.6	0.6	-0.7
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.3	0.5	-0.0	0.5	0.3	0.2	-0.1	0.0	0.3	-0.9	-0.5	0.6	0.3	-0.1	-0.2	1.1	-0.5
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.2	0.7	0.0	-0.1	0.3	0.4	0.1	0.5	0.4	0.1	0.2	0.9	0.4	0.1	0.4	1.0	-1.1
Fractured/broken bones in last 5 years	0.2	0.3	0.7	0.3	0.6	0.8	0.7	0.7	0.2	0.3	0.7	0.1	0.4	-0.6	0.7	0.5	-0.4	-0.3	-0.5
Age started oral contraceptive pill	0.2	0.3	1.2	0.3	-0.5	-0.2	-0.1	-0.4	-0.3	-0.3	-0.3	-0.7	-0.4	1.1	-0.3	-0.5	-0.4	1.1	-0.7
Commuting to job workplace: Cycle	0.2	0.2	1.1	-0.7	-0.3	-0.2	0.1	0.1	-0.4	-0.6	0.1	-1.0	-0.5	-0.3	0.1	-0.4	-0.7	0.3	0.2
Alzheimer’s Disease (including proxy)	0.1	0.1	0.4	0.6	-0.2	0.0	-0.3	-0.2	0.0	-0.0	-0.1	-0.0	-0.3	0.2	-0.1	-0.1	-0.6	0.2	-0.5
Lupus	0.1	0.1	0.7	0.3	-0.1	0.0	-0.2	-0.2	-0.3	-0.0	-0.1	-0.4	-0.1	0.5	-0.1	-0.2	0.2	0.8	-0.0
Blood Platelet Count	0.1	0.9	3.8	-0.8	-0.9	-0.6	-0.7	-0.6	0.2	-1.9	-0.7	-1.3	-0.8	0.4	-0.6	-1.0	-1.5	0.6	-1.4
Heel T-Score	0.1	1.2	5.8	1.2	1.1	-0.8	0.4	0.6	1.7	1.1	0.6	1.3	1.4	-0.0	0.6	0.6	2.4	-0.6	-1.1
Height	0.1	2.4	9.9	0.6	1.3	-0.1	0.8	0.8	0.7	0.9	0.4	3.1	2.4	-1.4	0.5	1.4	2.8	-2.7	0.9
Systolic Blood Pressure	0.1	0.4	2.0	-0.9	0.2	-0.1	0.2	0.3	0.2	-0.4	0.3	0.2	0.4	-1.2	0.4	0.2	1.4	-1.0	0.7
Respiratory disease	0.1	0.2	1.0	-0.7	-0.1	-0.3	-0.5	-0.4	-0.5	-0.1	-0.3	-0.1	-0.2	-0.3	-0.3	-0.2	-0.6	-0.2	1.0
Lung FEV1/FVC ratio	0.1	0.5	3.3	0.5	0.0	0.5	0.3	0.2	0.8	0.1	0.1	0.1	1.0	0.7	0.1	0.1	-1.6	0.6	-1.8
Lung FVC	0.1	0.5	2.9	1.2	-0.3	0.2	-0.1	-0.3	0.1	-0.4	-0.3	-0.5	0.1	1.2	-0.2	-0.1	-0.8	1.0	-1.7
Systolic blood pressure, automated reading	0.1	0.3	1.6	-1.3	-0.4	-0.2	-0.4	-0.3	-0.1	-0.7	-0.2	-0.4	-0.5	-0.5	-0.2	-0.4	0.4	-0.3	0.9
Medication: Metformin	0.1	0.2	0.7	0.8	0.1	0.5	0.0	0.0	-0.1	0.5	0.0	0.5	-0.4	0.4	0.0	0.1	0.9	0.2	0.9
Impedance of leg (right)	0.1	0.4	1.8	-1.3	-0.3	-0.5	-0.1	-0.1	-1.1	0.1	-0.1	-0.2	-0.5	-0.6	-0.1	-0.3	0.2	-0.5	1.4
Hand grip strength (right)	0.1	0.2	1.0	0.6	-0.1	0.3	0.2	0.0	0.1	-0.2	0.1	-0.1	-0.4	0.7	0.1	-0.2	-0.8	0.9	-1.0
Taking other prescription medications	0.1	0.2	0.6	0.6	0.1	0.5	0.2	0.1	0.5	0.3	0.2	0.4	-0.1	0.5	0.2	0.1	-0.8	0.6	-0.2
Impedance of leg (left)	0.1	0.5	1.2	-0.7	0.5	0.1	0.6	0.6	-0.6	0.9	0.6	0.7	0.2	-1.1	0.5	0.5	1.0	-1.1	1.1
Waist circumference	0.1	0.5	2.2	1.1	-0.3	-0.2	-0.3	-0.4	0.9	-0.4	-0.5	-0.3	-0.2	1.3	-0.5	-0.3	-0.7	1.2	-1.5
Had other major operations	0.1	0.1	0.8	-0.3	0.1	-0.1	0.0	0.1	0.1	-0.1	0.1	0.5	0.1	-0.4	0.1	0.0	-0.6	-0.4	0.9
Financial difficulties in last 2 years	0.1	0.2	1.0	-0.4	0.4	0.2	0.0	0.1	0.2	0.0	0.1	0.5	-0.2	-0.8	0.2	0.4	0.6	-1.0	0.2
Medication: Simvastatin	0.1	0.2	0.4	0.1	0.4	0.3	0.6	0.4	0.6	0.6	0.6	-0.3	0.3	-0.4	0.6	0.4	-0.0	-0.1	-0.2
Impedance of arm (right)	0.1	0.4	1.9	-0.3	0.4	0.3	0.7	0.6	-0.4	1.0	0.5	1.1	0.1	-0.6	0.4	0.4	1.4	-0.6	0.8
Trunk fat-free mass	0.1	0.6	2.4	1.5	0.9	0.6	0.6	0.7	1.0	0.1	0.4	1.2	1.4	-0.1	0.5	0.9	0.3	-0.6	-0.1
Alcohol intake versus 10 years previously	0.1	0.1	0.4	0.6	0.1	-0.3	-0.2	-0.2	0.3	0.3	-0.3	-0.1	0.3	0.4	-0.3	0.1	0.4	-0.1	-0.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.6	0.8	-0.0	-0.4	-0.2	-0.4	-0.3	0.2	-0.5	0.3	0.5	0.8	-0.5	-0.1	-0.5	0.1	-0.7
Impedance of arm (left)	0.1	0.3	0.8	-0.8	-0.4	-0.4	-0.2	-0.3	-0.9	0.5	-0.3	0.3	-0.6	0.0	-0.3	-0.4	0.8	-0.1	0.9
Trunk predicted mass	0.1	0.7	2.5	1.6	1.0	0.7	0.7	0.7	1.1	0.2	0.5	1.3	1.5	-0.2	0.6	1.0	0.3	-0.7	0.0
Breastfed as a baby	0.1	0.1	0.7	-0.3	-0.4	-0.4	0.3	0.0	0.4	0.1	0.0	-0.1	0.0	0.5	-0.0	-0.3	-0.5	0.4	-0.8
Hair/balding pattern: Pattern 4	0.1	0.1	0.6	-0.7	-0.1	0.1	0.0	0.1	-0.7	-0.1	0.0	-0.6	-0.8	-0.4	0.0	-0.2	-0.3	0.1	-0.5
Comparative height size at age 10	0.1	0.3	2.4	-0.6	-0.1	-0.3	-0.2	-0.2	-0.4	-0.5	-0.2	0.2	0.1	-0.5	-0.2	-0.0	1.0	-0.6	1.6
Supplements: Vitamin C	0.1	0.1	1.3	0.3	0.2	0.3	0.4	0.2	-0.2	0.1	0.2	0.0	0.0	0.1	0.2	0.2	1.1	-0.1	-0.1
Whole body fat-free mass	0.1	0.3	2.0	1.4	0.6	0.3	0.4	0.3	0.8	-0.1	0.1	0.9	1.0	0.2	0.2	0.6	0.2	-0.2	-0.3
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.4	0.4	0.1	0.2	0.4	0.2	-0.2	0.0	0.1	0.6	-0.0	0.3	0.1	0.1	0.3	0.1	-0.5
Long-standing illness, disability or infirmity	0.1	0.2	0.8	-0.5	-0.3	-0.6	-0.4	-0.3	0.0	-0.9	-0.4	0.0	-0.8	-0.1	-0.3	-0.4	-0.2	-0.2	-0.7
Mineral and other dietary supplements	0.1	0.2	0.6	0.7	0.3	-0.3	0.3	0.2	0.1	0.7	0.0	0.8	0.8	0.0	-0.0	0.3	0.5	-0.2	0.6
Asthma (self-reported)	0.1	0.1	0.4	0.4	-0.1	-0.6	-0.3	-0.3	-0.2	-0.1	-0.2	0.3	-0.2	0.6	-0.2	-0.1	-0.7	0.5	-0.0
Osteoporosis (self-reported)	0.1	0.1	1.1	-0.2	-0.2	-0.3	-0.0	-0.2	-0.1	-0.6	-0.2	-0.1	-0.0	0.1	-0.2	-0.3	-0.4	0.0	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.4	0.5	-0.2	-0.6	-0.4	-0.4	0.4	-0.3	-0.4	0.3	0.3	0.6	-0.4	-0.1	-0.5	0.1	-0.4
Whole body water mass	0.1	0.4	2.0	1.4	0.6	0.4	0.4	0.4	0.9	-0.1	0.2	0.9	1.0	0.1	0.2	0.6	0.2	-0.3	-0.2
Leg predicted mass (right)	0.1	0.3	1.9	1.4	0.3	0.0	0.1	-0.0	0.6	-0.1	-0.2	0.8	0.7	0.6	-0.2	0.3	0.3	0.2	-0.6
Number of self-reported non-cancer illnesses	0.1	0.1	0.8	0.5	0.2	-0.1	-0.1	0.0	0.9	-0.2	0.2	-0.1	0.2	0.1	0.2	0.2	-0.1	0.3	-0.7
High cholesterol (Self-reported)	0.1	0.1	0.7	0.3	0.2	0.1	0.1	0.2	0.4	0.8	0.3	0.3	-0.1	0.3	0.2	0.1	-0.3	0.2	-0.3
Diastolic blood pressure, automated reading	0.1	0.2	0.7	-0.7	-0.2	0.2	-0.2	-0.1	-0.5	-0.8	0.0	-0.8	-0.5	-0.4	0.1	-0.2	0.4	0.2	0.5
Unable to work because of sickness or disability	0.1	0.1	0.4	-0.0	-0.3	-0.3	-0.4	-0.4	-0.1	-0.1	-0.4	-0.6	-0.2	0.4	-0.4	-0.3	-0.5	0.5	-0.2
Cholesterol lowering medication	0.1	0.2	0.9	-0.7	-0.1	-0.5	-0.6	-0.3	0.3	-0.1	-0.3	-0.5	-0.0	-0.4	-0.3	-0.1	0.9	-0.5	0.7
Impedance of whole body	0.1	0.5	1.7	-1.3	-0.5	-0.8	-0.3	-0.4	-1.3	0.3	-0.4	0.0	-0.7	-0.2	-0.5	-0.5	0.7	-0.3	1.2
LDL Cholesterol	0.0	0.1	0.4	-0.3	-0.1	-0.2	-0.3	-0.2	-0.1	-0.1	-0.2	-0.4	0.3	-0.3	-0.2	-0.0	0.4	-0.1	0.6
Blood White Count	0.0	0.2	1.0	-0.1	0.2	0.3	0.3	0.3	0.4	-1.0	0.3	-0.1	-0.4	-0.8	0.4	0.4	0.8	-0.6	-0.2
Hair Pigment	0.0	1.3	3.9	0.7	-1.0	-2.0	-1.6	-1.5	-1.2	-0.7	-1.5	0.4	-0.6	1.7	-1.5	-1.1	0.3	0.5	-0.7
Leg fat-free mass (left)	0.0	0.2	0.9	0.9	-0.2	-0.3	-0.3	-0.4	0.2	-0.5	-0.6	0.3	0.3	0.8	-0.5	-0.1	-0.0	0.3	-0.3
Leg predicted mass (left)	0.0	0.2	0.8	0.9	-0.2	-0.3	-0.3	-0.4	0.3	-0.5	-0.6	0.3	0.2	0.8	-0.5	-0.1	-0.1	0.3	-0.3
Forced vital capacity (FVC)	0.0	0.2	0.6	0.6	0.0	-0.4	-0.2	-0.4	-0.7	-0.3	-0.6	0.5	0.3	0.3	-0.6	0.0	-0.1	-0.4	-0.1
Asthma	0.0	0.1	0.3	0.3	0.0	-0.4	-0.2	-0.1	-0.1	-0.3	-0.0	0.4	-0.1	0.3	0.0	-0.0	-0.5	0.2	-0.1
Arm fat-free mass (right)	0.0	0.1	0.6	0.8	0.2	0.0	-0.1	-0.1	0.4	-0.4	-0.2	0.3	0.6	0.1	-0.2	0.3	0.1	-0.2	0.1
Arm predicted mass (right)	0.0	0.2	0.9	1.0	-0.0	-0.1	-0.2	-0.2	0.5	-0.6	-0.4	0.0	0.4	0.6	-0.3	0.0	-0.4	0.2	-0.5
Leg fat-free mass (right)	0.0	0.2	1.6	1.2	0.3	0.0	0.1	0.0	0.6	-0.1	-0.2	0.9	0.8	0.4	-0.1	0.4	0.3	-0.0	-0.4
Basal metabolic rate	0.0	0.2	1.3	1.1	0.3	0.0	0.1	0.0	0.6	-0.4	-0.2	0.5	0.6	0.4	-0.1	0.3	0.1	-0.1	-0.3
Arm fat-free mass (left)	0.0	0.2	1.1	1.1	0.4	0.2	0.2	0.2	0.9	-0.4	0.0	0.5	0.7	0.1	0.1	0.4	0.0	-0.2	-0.4
Arm predicted mass (left)	0.0	0.2	0.9	1.0	0.5	0.2	0.3	0.3	0.7	-0.3	0.0	0.6	0.7	-0.1	0.1	0.5	0.1	-0.5	-0.2

Hub : Genes

ACTR5

Models

Trait associations