Best TWAS P=2.36e-12 · Best GWAS P=2.11e-10 conditioned to 0.0737
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C2orf47 | 0.05 | 0.02 | blup | 361 | 0.02 | 4.3e-03 | 6.2 | -7.0 | 2.4e-12 | -0.73 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Brain Caudate basal ganglia | TYW5 | 0.23 | 0.11 | lasso | 3 | 0.11 | 5.4e-04 | 4.5 | -5.5 | 3.9e-08 | -0.52 | 0.07 | 0.32 | FALSE |
| 3 | GTEx | Testis | C2orf69 | 0.14 | 0.09 | enet | 17 | 0.10 | 2.7e-05 | 6.2 | 6.4 | 1.7e-10 | 0.71 | 0.03 | 0.96 | FALSE |
| 4 | GTEx | Whole Blood | C2orf47 | 0.04 | 0.05 | lasso | 2 | 0.03 | 3.6e-04 | 6.3 | 6.3 | 4.0e-10 | 0.69 | 0.02 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | C2orf60 | 0.08 | 0.06 | enet | 11 | 0.06 | 1.4e-04 | 6.3 | -5.7 | 9.4e-09 | -0.64 | 0.01 | 0.94 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C2orf69 | 0.02 | 0.00 | blup | 35 | 0.01 | 2.6e-02 | 3.4 | 5.4 | 5.4e-08 | 0.59 | 0.02 | 0.76 | FALSE |
| 7 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | C2orf47 | 0.15 | 0.05 | blup | 39 | 0.05 | 7.6e-03 | 6.1 | -5.4 | 5.5e-08 | -0.64 | 0.01 | 0.97 | FALSE |
| 8 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | C2orf60 | 0.15 | 0.05 | enet | 12 | 0.08 | 8.2e-04 | 6.2 | -5.3 | 9.3e-08 | -0.59 | 0.01 | 0.98 | FALSE |