[Hub]/) : Traits : Schizophrenia (2018) :

chr2:197,134,790-199,079,806

Best TWAS P=6.66e-11 · Best GWAS P=4.03e-09 conditioned to 0.348

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SF3B1 0.06 0.07 enet 10 0.07 2.5e-09 5.6 5.7 1.0e-08 0.99 0.02 0.98 FALSE
2 GTEx Breast Mammary Tissue SF3B1 0.06 0.06 lasso 4 0.03 6.6e-03 5.8 6.0 2.0e-09 0.98 0.04 0.92 FALSE
3 GTEx Breast Mammary Tissue (Female) SF3B1 0.05 -0.01 lasso 3 -0.01 8.1e-01 5.9 6.1 1.3e-09 0.91 0.03 0.43 FALSE
4 GTEx Esophagus Mucosa SF3B1 0.04 0.02 lasso 4 0.01 5.7e-02 5.5 5.6 2.8e-08 0.98 0.06 0.82 FALSE
5 GTEx Nerve Tibial SF3B1 0.06 0.09 lasso 8 0.08 3.3e-06 5.9 5.5 3.7e-08 0.97 0.07 0.93 FALSE
6 GTEx Pituitary HSPD1 0.10 0.03 enet 12 0.06 1.3e-02 5.1 6.5 6.7e-11 0.69 0.07 0.40 TRUE
7 GTEx Testis SF3B1 0.10 0.07 enet 17 0.08 2.6e-04 5.6 5.5 4.3e-08 0.95 0.03 0.96 FALSE
8 NTR Blood ANKRD44 0.03 0.00 bslmm 417 0.02 2.7e-06 5.2 -6.0 2.2e-09 -0.61 0.07 0.88 FALSE
9 ROSMAP Brain Pre-frontal Cortex SF3B1 0.02 0.01 blup 336 0.01 6.2e-03 4.9 5.3 1.4e-07 0.93 0.06 0.91 FALSE
10 YFS Blood ANKRD44 0.02 0.00 blup 416 0.01 6.3e-04 2.8 -6.2 4.4e-10 -0.59 0.10 0.63 TRUE
11 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RFTN2 0.05 0.01 blup 61 0.02 3.1e-02 5.6 5.5 4.3e-08 0.92 0.02 0.67 FALSE