Best TWAS P=1.26e-08 · Best GWAS P=8.12e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | RABGAP1L | 0.14 | 0.02 | lasso | 4 | 0.02 | 0.01400 | -5.6 | -5.6 | 2.3e-08 | 0.96 | 0.01 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | DARS2 | 0.04 | 0.01 | lasso | 2 | 0.01 | 0.03300 | -3.6 | -5.2 | 1.6e-07 | 0.86 | 0.00 | 0.49 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | GAS5 | 0.03 | 0.03 | enet | 6 | 0.03 | 0.00033 | -5.6 | -5.7 | 1.3e-08 | 0.97 | 0.01 | 0.97 | TRUE |