[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr5:95,416,676-97,065,386

Best TWAS P=1.45e-08 · Best GWAS P=2.52e-10 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous ERAP1 0.31 0.17 lasso 9 0.22 6.5e-18 -4.5 -5.4 6.2e-08 0.69 0.94 0.06 FALSE
2 GTEx Adipose Visceral Omentum ERAP1 0.23 0.14 lasso 4 0.15 2.2e-08 -5.2 -5.1 2.9e-07 0.74 0.70 0.29 TRUE
3 GTEx Breast Mammary Tissue ERAP1 0.21 0.11 lasso 5 0.12 1.7e-06 -5.0 -5.2 2.0e-07 0.74 0.19 0.79 FALSE
4 GTEx Esophagus Gastroesophageal Junction AC008865.1 0.15 0.11 lasso 11 0.13 1.6e-05 4.2 5.2 2.0e-07 -0.31 0.19 0.05 TRUE
5 GTEx Nerve Tibial ERAP1 0.39 0.23 enet 32 0.26 1.1e-18 -4.5 -5.7 1.5e-08 0.63 0.98 0.02 TRUE
6 GTEx Spleen ERAP1 0.47 0.15 lasso 11 0.31 1.0e-08 -4.2 -5.2 1.7e-07 0.37 0.37 0.20 FALSE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma ERAP1 0.19 0.16 blup 130 0.23 1.0e-19 -4.5 -5.6 2.6e-08 0.72 0.98 0.02 FALSE
8 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma ERAP1 0.42 0.32 blup 131 0.43 1.0e-22 -4.5 -5.2 2.3e-07 0.71 0.89 0.11 TRUE
9 The Cancer Genome Atlas Esophageal Carcinoma ERAP1 0.24 0.09 blup 130 0.14 4.6e-05 -4.5 -5.3 1.4e-07 0.71 0.07 0.84 TRUE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ERAP1 0.39 0.30 lasso 9 0.37 9.0e-44 -4.2 -5.2 1.7e-07 0.67 0.99 0.00 TRUE