Best TWAS P=3.64e-09 · Best GWAS P=7.26e-10 conditioned to 0.00292
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | FER | 0.23 | 0.15 | enet | 7 | 0.18 | 3.3e-10 | -4.0 | -5.4 | 8.4e-08 | 0.55 | 0.62 | 0.36 | FALSE |
2 | GTEx | Artery Coronary | FER | 0.34 | 0.10 | lasso | 8 | 0.12 | 5.4e-05 | 5.1 | -5.4 | 5.8e-08 | 0.57 | 0.16 | 0.30 | FALSE |
3 | GTEx | Artery Tibial | FER | 0.14 | 0.06 | enet | 7 | 0.05 | 7.3e-05 | 5.1 | -5.9 | 3.6e-09 | 0.67 | 0.16 | 0.83 | TRUE |