Best TWAS P=9.71e-08 · Best GWAS P=3.18e-09 conditioned to 0.166
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | TBPL1 | 0.04 | 0.01 | lasso | 4 | 0.02 | 3.6e-07 | 5.3 | -5.3 | 1.3e-07 | 0.17 | 0.06 | 0.94 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SLC2A12 | 0.04 | 0.04 | lasso | 4 | 0.03 | 4.6e-07 | -5.3 | 5.2 | 2.0e-07 | -0.09 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TCF21 | 0.04 | 0.01 | blup | 40 | 0.02 | 9.9e-06 | 2.6 | -5.3 | 9.7e-08 | 0.79 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | TBPL1 | 0.08 | 0.06 | lasso | 3 | 0.04 | 2.3e-03 | -5.3 | 5.2 | 2.6e-07 | -0.10 | 0.01 | 0.97 | FALSE |