Best TWAS P=4.23e-08 · Best GWAS P=9.93e-06 conditioned to 0.745
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells EBV-transformed lymphocytes | RAC1 | 0.21 | 0.11 | enet | 11 | 0.14 | 1.9e-05 | -3.9 | 5.4 | 5.6e-08 | -0.60 | 0.02 | 0.62 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | RAC1 | 0.20 | 0.07 | enet | 15 | 0.15 | 2.5e-11 | -4.0 | 5.5 | 4.2e-08 | -0.77 | 0.02 | 0.80 | TRUE |