Best TWAS P=4.94e-13 · Best GWAS P=6.75e-13 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Transverse | LFNG | 0.25 | 0.20 | lasso | 3 | 0.17 | 1.1e-08 | 7.2 | 7.2 | 4.9e-13 | 1.00 | 0.00 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Soft Tissue Sarcoma | LFNG | 0.13 | 0.02 | blup | 43 | 0.05 | 8.0e-04 | 5.3 | -5.3 | 1.4e-07 | -0.52 | 0.01 | 0.15 | FALSE |