[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr7:76,506,844-77,966,572

Best TWAS P=8.24e-10 · Best GWAS P=1.87e-09 conditioned to 0.0174

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PTPN12	0.21	0.09	lasso	9	0.14	5.4e-17	-5.4	5.4	7.8e-08	-0.72	0.30	0.70	FALSE
2	GTEx	Adipose Subcutaneous	PTPN12	0.17	0.08	lasso	7	0.10	7.8e-09	3.7	5.7	1.3e-08	-0.74	0.17	0.83	FALSE
3	GTEx	Adipose Visceral Omentum	PTPN12	0.19	0.04	enet	28	0.02	2.5e-02	-5.9	6.1	9.7e-10	-0.79	0.01	0.98	FALSE
4	GTEx	Adrenal Gland	PTPN12	0.16	0.10	lasso	4	0.04	1.0e-02	-5.4	5.5	3.3e-08	-0.88	0.03	0.93	FALSE
5	GTEx	Artery Aorta	PTPN12	0.22	0.03	enet	28	0.10	3.0e-06	4.3	6.0	1.9e-09	-0.67	0.05	0.94	FALSE
6	GTEx	Artery Coronary	PTPN12	0.33	0.08	enet	26	0.24	1.6e-08	3.2	5.4	8.0e-08	-0.66	0.12	0.83	FALSE
7	GTEx	Artery Tibial	PTPN12	0.25	0.13	lasso	8	0.12	1.8e-09	-6.0	6.0	1.9e-09	-0.99	0.01	0.99	FALSE
8	GTEx	Cells Transformed fibroblasts	PTPN12	0.19	0.15	lasso	4	0.18	1.7e-13	3.9	5.5	3.8e-08	-0.74	0.39	0.61	FALSE
9	GTEx	Colon Sigmoid	PTPN12	0.24	0.04	lasso	8	0.08	1.2e-03	4.3	5.8	7.2e-09	-0.68	0.05	0.80	FALSE
10	GTEx	Colon Transverse	PTPN12	0.17	0.12	lasso	6	0.10	1.8e-05	-5.4	5.8	8.9e-09	-0.84	0.04	0.94	FALSE
11	GTEx	Esophagus Muscularis	PTPN12	0.34	0.17	enet	48	0.20	4.3e-12	-5.3	6.1	8.2e-10	-0.70	0.12	0.88	TRUE
12	GTEx	Heart Atrial Appendage	PTPN12	0.20	0.09	enet	17	0.10	2.8e-05	3.9	5.5	4.0e-08	-0.64	0.04	0.89	FALSE
13	GTEx	Lung	PTPN12	0.10	0.05	enet	11	0.07	5.1e-06	-5.4	5.8	7.4e-09	-0.83	0.13	0.86	FALSE
14	GTEx	Nerve Tibial	PTPN12	0.18	0.13	enet	20	0.14	2.9e-10	-5.3	5.7	1.4e-08	-0.80	0.14	0.86	FALSE
15	GTEx	Pancreas	PTPN12	0.26	0.13	lasso	3	0.08	2.7e-04	-5.3	5.4	5.4e-08	-0.79	0.12	0.71	FALSE
16	GTEx	Skin Sun Exposed Lower leg	PTPN12	0.28	0.17	lasso	8	0.18	1.8e-14	3.9	5.1	2.9e-07	-0.59	0.99	0.01	FALSE
17	GTEx	Spleen	PTPN12	0.41	0.07	lasso	11	0.14	2.2e-04	-5.3	5.3	1.2e-07	-0.78	0.05	0.90	FALSE
18	GTEx	Thyroid	PTPN12	0.13	0.08	lasso	7	0.08	9.5e-07	-5.4	6.1	1.0e-09	-0.83	0.04	0.96	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	PHTF2	0.02	0.01	lasso	1	0.01	3.0e-03	-6.0	6.0	2.1e-09	-1.00	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PHTF2	0.02	0.03	lasso	1	0.02	8.0e-04	-5.8	5.8	6.9e-09	-0.97	0.02	0.95	FALSE
21	The Cancer Genome Atlas	Soft Tissue Sarcoma	PHTF2	0.06	0.04	blup	72	0.04	2.0e-03	-5.9	5.4	7.3e-08	-0.85	0.02	0.89	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	PTPN12	0.04	0.04	enet	4	0.04	1.0e-04	-5.3	5.4	7.4e-08	-0.91	0.01	0.98	FALSE