[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr7:74,339,397-75,842,792

Best TWAS P=3.77e-08 · Best GWAS P=1.94e-07 conditioned to 0.276

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PMS2P3 0.15 0.12 lasso 3 0.10 9.8e-09 -5.2 -5.1 2.8e-07 0.99 0 1.00 FALSE
2 GTEx Brain Cerebellar Hemisphere TRIM73 0.35 0.28 enet 25 0.25 3.6e-07 -4.9 -5.5 3.8e-08 0.84 0 0.99 TRUE
3 GTEx Brain Cerebellum TRIM73 0.24 0.06 enet 12 0.14 8.2e-05 -5.2 -5.3 1.1e-07 0.85 0 0.96 FALSE
4 GTEx Cells Transformed fibroblasts PMS2P3 0.23 0.15 lasso 6 0.15 1.4e-11 -5.2 -5.3 9.8e-08 0.97 0 1.00 FALSE
5 GTEx Cells Transformed fibroblasts STAG3L1 0.22 0.17 lasso 4 0.18 2.6e-13 -4.9 -5.1 3.1e-07 0.94 0 0.99 FALSE
6 GTEx Colon Sigmoid STAG3L1 0.30 0.18 lasso 4 0.18 8.5e-07 -4.9 -5.1 2.9e-07 0.94 0 0.98 FALSE
7 GTEx Esophagus Muscularis TRIM73 0.12 0.07 lasso 2 0.05 3.5e-04 -5.2 -5.2 1.7e-07 1.00 0 0.99 FALSE
8 GTEx Nerve Tibial PMS2P3 0.29 0.13 enet 4 0.18 1.1e-12 -4.8 -5.2 2.5e-07 0.90 0 1.00 FALSE
9 GTEx Stomach PMS2P3 0.16 0.07 lasso 5 0.09 3.7e-05 -4.8 -5.2 2.2e-07 0.94 0 0.99 FALSE
10 METSIM Adipose TRIM73 0.11 0.11 lasso 5 0.12 8.6e-18 -5.2 -5.2 1.5e-07 0.97 0 1.00 FALSE
11 ROSMAP Brain Pre-frontal Cortex POM121C 0.36 0.26 lasso 7 0.27 2.8e-34 -4.9 -5.2 2.3e-07 0.95 0 1.00 FALSE
12 ROSMAP Brain Pre-frontal Cortex PMS2P2 0.17 0.08 enet 8 0.08 6.0e-10 -4.9 -5.2 2.0e-07 0.95 0 1.00 FALSE
13 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma PMS2L3 0.23 0.14 lasso 2 0.14 1.3e-04 -4.9 -5.3 1.1e-07 0.94 0 0.63 FALSE