Best TWAS P=3.27e-09 · Best GWAS P=3.59e-12 conditioned to 5.28e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | SNX16 | 0.40 | 0.17 | lasso | 12 | 0.16 | 1.7e-06 | 5 | 5.5 | 3.8e-08 | -0.47 | 0.68 | 0.30 | FALSE |
2 | GTEx | Colon Transverse | SNX16 | 0.28 | 0.36 | lasso | 5 | 0.38 | 5.5e-19 | 5 | 5.9 | 3.3e-09 | -0.66 | 0.98 | 0.02 | TRUE |
3 | GTEx | Esophagus Gastroesophageal Junction | SNX16 | 0.37 | 0.39 | lasso | 8 | 0.39 | 2.6e-15 | 5 | 5.1 | 3.0e-07 | -0.51 | 0.99 | 0.01 | FALSE |
4 | GTEx | Stomach | SNX16 | 0.26 | 0.16 | lasso | 10 | 0.18 | 4.5e-09 | 5 | 5.2 | 2.2e-07 | -0.54 | 0.99 | 0.01 | FALSE |
5 | GTEx | Testis | SNX16 | 0.53 | 0.62 | lasso | 6 | 0.63 | 6.1e-35 | 5 | 5.1 | 3.1e-07 | -0.52 | 0.99 | 0.01 | FALSE |