Best TWAS P=3.65e-09 · Best GWAS P=2.36e-13 conditioned to 5.11e-12
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellum | NDUFAF6 | 0.28 | 0.13 | lasso | 7 | 0.14 | 5.8e-05 | 5.2 | -5.2 | 2.6e-07 | -0.07 | 0.06 | 0.91 | FALSE |
2 | GTEx | Whole Blood | TP53INP1 | 0.07 | 0.04 | enet | 13 | 0.02 | 2.9e-03 | 5.2 | 5.9 | 3.7e-09 | 0.08 | 0.05 | 0.94 | TRUE |
3 | YFS | Blood | TP53INP1 | 0.03 | 0.02 | lasso | 5 | 0.02 | 8.0e-07 | 4.2 | 5.6 | 1.8e-08 | 0.03 | 0.01 | 0.99 | FALSE |
4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | TP53INP1 | 0.06 | 0.02 | lasso | 3 | 0.03 | 2.8e-03 | 5.2 | 5.2 | 1.8e-07 | 0.07 | 0.06 | 0.77 | FALSE |