Best TWAS P=1.26e-07 · Best GWAS P=2.06e-08 conditioned to 0.0309
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | CBWD1 | 0.31 | 0.17 | enet | 8 | 0.23 | 1.7e-22 | -4.7 | -5.1 | 2.7e-07 | -0.87 | 0.03 | 0.96 | FALSE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CBWD1 | 0.11 | 0.11 | lasso | 3 | 0.13 | 2.1e-14 | -4.8 | -5.3 | 1.5e-07 | -0.88 | 0.04 | 0.95 | FALSE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | CBWD1 | 0.10 | 0.10 | blup | 30 | 0.11 | 1.9e-05 | -4.6 | -5.2 | 1.8e-07 | -0.87 | 0.02 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CBWD1 | 0.10 | 0.08 | enet | 7 | 0.11 | 2.2e-11 | -4.8 | -5.3 | 1.3e-07 | -0.84 | 0.02 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | CBWD1 | 0.12 | 0.03 | blup | 30 | 0.06 | 3.4e-03 | -4.6 | -5.2 | 2.4e-07 | -0.88 | 0.00 | 0.89 | FALSE |