Best TWAS P=1.68e-08 · Best GWAS P=1.31e-06 conditioned to 0.102
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | UBAP1 | 0.16 | 0.04 | enet | 38 | 0.13 | 2.3e-16 | 4.7 | 5.6 | 1.7e-08 | 0.30 | 0.03 | 0.94 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PRSS3 | 0.04 | 0.01 | blup | 37 | 0.02 | 4.5e-03 | 3.0 | 5.2 | 2.1e-07 | 0.55 | 0.00 | 0.12 | TRUE |