[Hub]/) : Traits : Systolic Blood Pressure :

chr12:89,116,708-90,799,212

Best TWAS P=7.14e-51 · Best GWAS P=5.78e-71 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous POC1B 0.12 0.08 lasso 9 0.09 1.7e-07 -8.77 8.1 4.4e-16 -0.58 0.96 0.03 FALSE
2 GTEx Adrenal Gland RP11-981P6.1 0.33 0.29 lasso 3 0.19 2.2e-07 -8.77 -9.8 9.8e-23 0.54 0.99 0.00 TRUE
3 GTEx Artery Aorta POC1B 0.12 0.07 lasso 5 0.04 3.9e-03 -8.74 6.3 3.9e-10 -0.53 0.22 0.14 FALSE
4 GTEx Artery Tibial ATP2B1 0.08 0.01 enet 10 0.03 3.5e-03 -17.77 -15.0 7.1e-51 0.87 0.01 0.97 TRUE
5 GTEx Artery Tibial RP11-981P6.1 0.07 0.06 lasso 1 0.03 1.3e-03 -8.55 -8.6 1.2e-17 0.57 0.60 0.02 FALSE
6 GTEx Brain Cerebellum RP11-981P6.1 0.47 0.27 enet 41 0.21 7.1e-07 0.81 -6.2 6.7e-10 0.46 0.75 0.16 FALSE
7 GTEx Colon Sigmoid RP11-981P6.1 0.19 0.12 lasso 4 0.11 9.7e-05 -8.77 -8.4 4.9e-17 0.58 0.31 0.11 FALSE
8 GTEx Colon Transverse RP11-981P6.1 0.14 0.05 enet 26 0.05 1.9e-03 -8.83 -6.8 8.3e-12 0.50 0.25 0.39 TRUE
9 GTEx Esophagus Muscularis RP11-981P6.1 0.18 0.10 lasso 3 0.06 2.9e-04 -8.75 -8.6 1.2e-17 0.59 0.82 0.11 TRUE
10 GTEx Lung RP11-981P6.1 0.08 0.01 lasso 3 0.01 3.9e-02 -8.77 -10.6 2.8e-26 0.61 0.23 0.32 TRUE
11 GTEx Nerve Tibial POC1B 0.30 0.18 lasso 6 0.22 1.0e-15 6.02 8.6 1.3e-17 -0.44 1.00 0.00 FALSE
12 GTEx Prostate POC1B 0.25 0.00 enet 37 0.01 1.6e-01 -14.95 8.2 3.0e-16 -0.50 0.02 0.64 FALSE
13 GTEx Spleen RP11-981P6.1 0.28 0.18 lasso 13 0.14 2.1e-04 -8.55 -9.1 7.6e-20 0.61 0.19 0.57 FALSE
14 GTEx Thyroid RP11-981P6.1 0.24 0.25 lasso 5 0.26 3.9e-20 -8.75 -9.7 3.5e-22 0.64 1.00 0.00 FALSE
15 METSIM Adipose POC1B 0.07 0.03 bslmm 381 0.03 5.2e-05 -8.83 10.6 4.5e-26 -0.56 0.90 0.03 TRUE
16 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LOC338758 0.14 0.00 enet 6 0.01 6.2e-02 3.98 -10.2 1.4e-24 0.32 0.01 0.07 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma GALNT4 0.05 0.05 lasso 2 0.04 8.7e-06 6.03 6.3 2.6e-10 -0.24 0.84 0.01 TRUE