Best TWAS P=4.76e-08 · Best GWAS P=2.45e-12 conditioned to 5.49e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | PAWR | 0.05 | 0.03 | blup | 303 | 0.04 | 0.00001 | 2.2 | 5.2 | 2.4e-07 | -0.50 | 0.91 | 0.05 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PAWR | 0.04 | 0.02 | lasso | 3 | 0.01 | 0.01480 | 5.5 | 5.1 | 2.9e-07 | -0.19 | 0.00 | 0.84 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | PAWR | 0.08 | 0.03 | lasso | 1 | 0.03 | 0.00076 | 5.5 | 5.5 | 4.8e-08 | -0.16 | 0.00 | 0.96 | TRUE |