Best TWAS P=8.28e-10 · Best GWAS P=4.97e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Sigmoid | MYLPF | 0.24 | 0.09 | lasso | 3 | 0.05 | 9.0e-03 | -6.2 | -6.1 | 8.3e-10 | 1.00 | 0 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | YPEL3 | 0.15 | 0.00 | blup | 20 | 0.05 | 2.9e-03 | 3.6 | 6.0 | 2.6e-09 | -0.59 | 0 | 0.39 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | GDPD3 | 0.10 | 0.05 | lasso | 5 | 0.05 | 1.9e-05 | -5.2 | 5.7 | 1.5e-08 | -0.91 | 0 | 1.00 | FALSE |