[Hub]/) : Traits : Systolic Blood Pressure :

chr16:65,813,302-67,691,515

Best TWAS P=8.56e-10 · Best GWAS P=1.71e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa FAM96B 0.08 0.09 lasso 4 0.09 1.1e-06 6.0 -5.7 1.0e-08 -0.97 0.00 1.00 FALSE
2 GTEx Esophagus Mucosa CES2 0.20 0.18 lasso 6 0.20 1.1e-13 6.0 -6.1 8.9e-10 -0.98 0.00 1.00 TRUE
3 GTEx Esophagus Mucosa RP11-361L15.4 0.18 0.17 lasso 5 0.20 2.5e-13 6.0 -6.1 8.6e-10 -0.98 0.00 1.00 FALSE
4 GTEx Lung RP11-403P17.5 0.17 0.05 enet 26 0.07 2.9e-06 6.0 5.8 6.2e-09 0.75 0.00 1.00 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CDH16 0.02 0.01 blup 37 0.01 3.4e-02 4.9 -5.4 5.6e-08 -0.77 0.02 0.65 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CES2 0.03 0.01 blup 30 0.01 8.2e-03 4.6 -5.2 1.9e-07 -0.69 0.02 0.46 FALSE
7 The Cancer Genome Atlas Thyroid Carcinoma CCDC79 0.11 0.03 blup 46 0.03 7.5e-04 5.7 -5.5 4.0e-08 -0.91 0.00 0.94 FALSE