[Hub]/) : Traits : Systolic Blood Pressure :

chr17:29,959,697-31,506,495

Best TWAS P=7.05e-09 · Best GWAS P=2.04e-08 conditioned to 0.254

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa C17orf75 0.11 0.10 lasso 2 0.09 1.2e-06 5.3 -5.3 1.3e-07 -0.94 0.02 0.98 FALSE
2 GTEx Testis PSMD11 0.42 0.38 lasso 4 0.37 1.6e-17 5.5 -5.4 7.4e-08 -0.98 0.02 0.98 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma C17orf75 0.02 0.02 lasso 1 0.02 1.5e-04 5.3 -5.2 1.5e-07 -0.98 0.00 0.99 FALSE
4 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma C17orf75 0.07 0.07 blup 24 0.06 4.3e-04 5.3 -5.3 9.8e-08 -0.90 0.01 0.89 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C17orf75 0.08 0.04 blup 24 0.06 3.1e-07 5.3 -5.3 1.0e-07 -0.82 0.00 0.99 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C17orf75 0.17 0.16 lasso 3 0.16 1.3e-17 5.3 -5.4 8.4e-08 -0.98 0.00 0.99 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma C17orf75 0.03 0.03 blup 24 0.03 3.2e-04 5.3 -5.4 6.1e-08 -0.93 0.00 0.93 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma C17orf75 0.06 0.05 blup 24 0.05 2.8e-06 5.4 -5.8 7.1e-09 -0.87 0.00 0.99 TRUE
9 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C17orf75 0.06 0.04 blup 24 0.04 1.1e-03 5.4 -5.4 7.9e-08 -0.94 0.00 0.92 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma C17orf75 0.15 0.10 blup 24 0.11 3.0e-05 5.3 -5.3 1.2e-07 -0.91 0.00 0.98 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma C17orf75 0.21 0.20 enet 12 0.22 1.1e-20 5.3 -5.3 1.1e-07 -0.94 0.00 1.00 FALSE