Best TWAS P=9.66e-12 · Best GWAS P=3.36e-12 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | ARVCF | 0.30 | 0.22 | lasso | 3 | 0.23 | 6.0e-13 | 6.9 | -6.7 | 2.0e-11 | -0.97 | 0.01 | 0.99 | FALSE |
2 | GTEx | Artery Tibial | ARVCF | 0.17 | 0.10 | lasso | 5 | 0.11 | 7.8e-09 | 6.9 | -6.8 | 9.7e-12 | -0.95 | 0.01 | 0.99 | TRUE |
3 | GTEx | Artery Tibial | AC006547.14 | 0.09 | 0.00 | lasso | 4 | 0.00 | 6.9e-01 | 6.9 | -6.8 | 1.2e-11 | -0.83 | 0.02 | 0.61 | TRUE |
4 | GTEx | Brain Cerebellum | ARVCF | 0.29 | 0.15 | lasso | 3 | 0.11 | 3.9e-04 | -5.0 | 5.7 | 1.1e-08 | 0.74 | 0.07 | 0.86 | TRUE |
5 | GTEx | Brain Cerebellum | AC006547.13 | 0.24 | -0.01 | enet | 15 | 0.00 | 3.4e-01 | 4.5 | 5.7 | 1.3e-08 | 0.76 | 0.04 | 0.37 | TRUE |
6 | GTEx | Nerve Tibial | ARVCF | 0.19 | 0.09 | lasso | 6 | 0.13 | 2.3e-09 | 6.9 | 6.7 | 2.2e-11 | 0.94 | 0.01 | 0.99 | FALSE |
7 | GTEx | Skin Not Sun Exposed Suprapubic | ARVCF | 0.12 | 0.00 | lasso | 3 | 0.00 | 5.5e-01 | 6.1 | 5.3 | 1.1e-07 | 0.86 | 0.04 | 0.81 | FALSE |
8 | GTEx | Skin Sun Exposed Lower leg | ARVCF | 0.09 | 0.00 | lasso | 3 | 0.00 | 3.8e-01 | 5.7 | 5.8 | 7.1e-09 | 0.84 | 0.05 | 0.21 | FALSE |
9 | GTEx | Thyroid | ARVCF | 0.25 | 0.09 | enet | 39 | 0.20 | 7.5e-15 | 6.9 | 5.4 | 7.4e-08 | 0.73 | 0.00 | 1.00 | FALSE |
10 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARVCF | 0.03 | 0.01 | blup | 116 | 0.01 | 1.1e-02 | -1.5 | -6.3 | 3.0e-10 | -0.62 | 0.02 | 0.27 | TRUE |