[Hub]/) : Traits : Systolic Blood Pressure :

chr22:19,262,852-20,330,744

Best TWAS P=9.66e-12 · Best GWAS P=3.36e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ARVCF 0.30 0.22 lasso 3 0.23 6.0e-13 6.9 -6.7 2.0e-11 -0.97 0.01 0.99 FALSE
2 GTEx Artery Tibial ARVCF 0.17 0.10 lasso 5 0.11 7.8e-09 6.9 -6.8 9.7e-12 -0.95 0.01 0.99 TRUE
3 GTEx Artery Tibial AC006547.14 0.09 0.00 lasso 4 0.00 6.9e-01 6.9 -6.8 1.2e-11 -0.83 0.02 0.61 TRUE
4 GTEx Brain Cerebellum ARVCF 0.29 0.15 lasso 3 0.11 3.9e-04 -5.0 5.7 1.1e-08 0.74 0.07 0.86 TRUE
5 GTEx Brain Cerebellum AC006547.13 0.24 -0.01 enet 15 0.00 3.4e-01 4.5 5.7 1.3e-08 0.76 0.04 0.37 TRUE
6 GTEx Nerve Tibial ARVCF 0.19 0.09 lasso 6 0.13 2.3e-09 6.9 6.7 2.2e-11 0.94 0.01 0.99 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic ARVCF 0.12 0.00 lasso 3 0.00 5.5e-01 6.1 5.3 1.1e-07 0.86 0.04 0.81 FALSE
8 GTEx Skin Sun Exposed Lower leg ARVCF 0.09 0.00 lasso 3 0.00 3.8e-01 5.7 5.8 7.1e-09 0.84 0.05 0.21 FALSE
9 GTEx Thyroid ARVCF 0.25 0.09 enet 39 0.20 7.5e-15 6.9 5.4 7.4e-08 0.73 0.00 1.00 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma ARVCF 0.03 0.01 blup 116 0.01 1.1e-02 -1.5 -6.3 3.0e-10 -0.62 0.02 0.27 TRUE