Best TWAS P=5.5e-11 · Best GWAS P=2.35e-14 conditioned to 1.33e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | -5.0 | -5.3 | 8.9e-08 | 0.55 | 0.98 | 0.02 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | -6.8 | -6.0 | 2.0e-09 | 0.61 | 0.28 | 0.72 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | -6.7 | -6.5 | 8.8e-11 | 0.71 | 0.29 | 0.69 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CADM2 | 0.14 | 0.05 | blup | 339 | 0.09 | 2.7e-04 | -7.0 | -6.6 | 5.5e-11 | 0.67 | 0.10 | 0.60 | TRUE |