Best TWAS P=8.24e-12 · Best GWAS P=4.05e-17 conditioned to 0.000311
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | ENPEP | 0.17 | 0.01 | lasso | 6 | 0.00 | 5.0e-01 | -2.0 | -6.0 | 2.2e-09 | -0.52 | 0.02 | 0.72 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | ENPEP | 0.16 | 0.08 | lasso | 7 | 0.10 | 5.3e-08 | 6.1 | -6.1 | 9.3e-10 | -0.18 | 0.98 | 0.00 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | ENPEP | 0.04 | 0.01 | blup | 486 | 0.01 | 5.7e-03 | 5.9 | -6.8 | 8.2e-12 | -0.37 | 0.17 | 0.38 | TRUE |