Hub : Genes

ENPEP

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1660	0.0570	3.0e-03	0.012	NA	-0.005	NA	-0.003	7.5e-02	NA	7.0e-01	NA	5.0e-01
2	GTEx	Cells Transformed fibroblasts	0.1600	0.0450	6.1e-05	0.080	NA	0.092	NA	0.101	1.4e-06	NA	2.3e-07	NA	5.3e-08
3	GTEx	Esophagus Gastroesophageal Junction	0.2820	0.0940	4.9e-03	-0.005	NA	-0.008	NA	-0.004	5.2e-01	NA	8.4e-01	NA	5.0e-01
4	GTEx	Esophagus Mucosa	0.2490	0.0710	4.2e-04	0.004	NA	0.006	NA	0.020	1.7e-01	NA	1.2e-01	NA	1.7e-02
5	GTEx	Esophagus Muscularis	0.1640	0.0500	4.7e-04	0.061	NA	0.017	NA	0.093	1.4e-04	NA	2.9e-02	NA	2.9e-06
6	GTEx	Lung	0.4788	0.0490	0.0e+00	0.332	NA	0.393	NA	0.405	3.9e-26	NA	7.3e-32	NA	5.0e-33
7	GTEx	Muscle Skeletal	0.1294	0.0440	3.1e-03	0.095	NA	0.097	NA	0.104	1.3e-09	NA	1.0e-09	NA	2.2e-10
8	ROSMAP	Brain Pre-frontal Cortex	0.0403	0.0184	1.6e-02	0.005	0.014	0.003	0.011	0.003	6.1e-02	0.00570	1.3e-01	0.012	1.1e-01
9	TCGA	Bladder Urothelial Carcinoma	0.0620	0.0270	6.8e-04	0.032	0.038	0.030	NA	0.025	8.8e-04	0.00033	1.2e-03	NA	2.9e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.2	1.9	6.1	-0.6	-2.5	2.3	-0.2	0.8	0.9	0.4	-1.8	-0.6
Bipolar Disorder or Schizophrenia	0.8	2.0	9.5	0.2	-2.1	3.1	-0.5	-0.2	-0.3	0.6	-1.6	0.7
Depressed Affect (Nagel 2018)	2.0	4.2	11.9	-0.5	2.0	1.2	-0.3	-3.4	-3.4	-0.5	1.2	2.6
Depression (Nagel 2018)	0.9	1.4	3.7	-0.0	0.2	1.2	-0.1	-1.9	-1.9	0.3	0.4	1.8
Intelligence (Savage-Jansen 2018)	1.0	3.1	9.0	1.7	-1.6	-0.7	-0.1	3.0	3.0	-0.3	0.3	-2.1
Neuroticism (Nagel 2018)	1.1	2.6	7.0	-1.0	1.5	1.0	0.4	-2.6	-2.6	-1.3	0.8	1.5
Schizophrenia (2018)	0.6	1.1	4.8	0.6	-0.6	2.2	-0.5	-0.9	-1.0	0.4	-0.4	1.5
Schizophrenia vs Biploar Disorder	0.9	1.2	2.6	0.2	0.8	-1.4	-0.5	-1.0	-1.0	1.3	1.2	1.6
Worry (Nagel 2018)	0.4	0.8	3.1	-0.4	1.4	0.4	1.0	-0.6	-0.7	-1.8	0.6	0.1
Alzheimer’s Disease (in mother)	0.4	0.5	1.4	0.4	0.2	0.1	1.0	-0.5	-0.6	-1.1	0.5	1.2
Alzheimer’s Disease (in father)	0.3	0.4	1.2	-0.9	-0.6	-0.7	0.3	-0.1	-0.2	-1.1	-0.5	-0.4
Alzheimer’s Disease (including proxy)	0.3	0.5	1.3	-0.1	-1.1	-0.5	1.1	0.6	0.3	-0.9	-0.2	-0.3
Crohns Disease (2017)	0.3	0.8	1.9	0.1	0.3	0.9	-0.6	-1.4	-1.4	0.5	0.5	1.1
Irritable Bowel Disease (IBD)	0.1	0.3	0.7	0.4	-0.8	0.7	-0.3	-0.2	0.1	0.7	-0.7	0.7
Ulcerative Colitis (UC)	0.4	0.8	1.7	0.6	-1.2	-0.0	0.4	0.9	1.2	1.1	-1.3	0.2
Major Depression (MDD)	0.8	0.9	2.5	0.1	0.1	-1.6	1.5	1.2	1.0	0.2	-0.2	-1.0
Reaction Time	2.5	4.7	8.7	-2.1	1.0	1.3	-2.9	-2.9	-2.9	-0.7	-1.7	2.5
Verbal and Numeric Reasoning (VNR)	1.1	2.6	8.2	1.1	-0.8	-1.2	0.2	2.8	2.9	0.1	0.6	-2.0
Breast Cancer	1.1	2.6	8.9	0.5	0.8	0.2	2.7	1.1	1.0	-3.0	1.9	-0.8
Ovarian Cancer	1.7	2.2	6.0	-1.3	-1.7	0.7	0.2	1.3	1.4	-0.2	-2.3	-2.4
Prostate Cancer	0.6	0.9	3.0	1.7	-0.5	-0.8	0.6	1.1	1.4	-0.2	-0.5	-0.4
Age at First Birth	1.6	2.4	5.0	1.1	-0.1	-0.8	1.6	2.1	2.0	2.2	0.7	-1.7
Bipolar Disorder (2011)	0.4	0.4	1.2	-0.2	-0.8	0.0	-0.6	-0.9	-0.9	0.1	-1.1	-0.3
Body Mass Index (BMI) (2010)	0.5	0.7	2.8	-0.3	-0.0	1.7	0.9	0.3	0.3	1.0	-1.0	-0.3
Coronary Artery Disease (CAD)	0.4	0.5	2.0	-0.2	-0.5	-0.2	-0.9	0.6	0.5	-1.4	-0.5	-0.4
Crohns Disease (2012)	0.2	0.2	0.8	0.4	0.6	0.1	-0.4	-0.3	-0.3	0.4	0.6	0.9
Mean Putamen Volume	0.5	0.5	1.6	0.7	0.6	-0.2	-0.7	0.6	0.4	-0.9	1.3	0.5
Fasting Glucose	1.4	1.6	5.1	-0.3	-0.8	0.2	0.9	1.9	1.9	-0.7	0.2	-2.3
HbA1C	1.5	1.7	5.1	-1.9	0.0	1.4	-2.2	-1.1	-1.2	0.7	-1.1	-0.7
HDL Cholesterol	0.4	0.6	2.2	1.2	0.1	0.5	-1.5	0.3	0.6	-0.8	-0.1	0.9
LDL Cholesterol	1.0	1.5	4.1	0.8	-0.3	-0.1	0.6	2.0	2.0	-0.8	-1.1	-1.6
Lupus	1.2	1.8	4.6	-0.2	1.7	-0.4	-1.4	-2.1	-2.0	-0.3	-0.3	1.6
Neuroticism (2016)	1.0	1.5	2.8	-1.5	0.2	-0.5	-1.3	-1.7	-1.7	-0.8	-1.1	1.2
Primary Biliary Cirrhosis	0.6	0.9	2.3	0.2	0.6	1.5	0.2	1.1	1.0	0.7	0.9	-1.4
Rheumatoid Arthritis	1.4	1.9	6.7	0.0	-0.1	-2.6	0.5	1.9	1.7	-1.1	0.1	-1.6
Schizophrenia (2014)	0.5	1.1	4.3	-0.1	-1.0	2.1	-1.0	-0.7	-0.8	0.5	-0.6	1.4
Triglycerides	0.4	0.7	3.5	-0.2	0.5	1.2	1.9	-0.2	-0.3	-0.5	0.4	-0.5
Type 2 Diabetes (T2D) (2012)	1.2	1.4	3.8	0.9	-0.6	1.5	1.9	1.4	1.4	0.4	-1.0	0.3
Ulcerative Colitis	0.5	0.7	2.6	0.4	-0.4	0.3	-0.0	1.4	1.6	0.9	-0.8	-0.0
Blood Eosinophil Count	0.3	2.1	4.6	0.3	1.1	0.7	-2.1	-1.8	-1.8	0.9	-0.9	2.1
Blood Platelet Count	0.4	4.9	18.4	4.3	2.6	-0.8	2.0	2.6	2.2	-1.4	-0.1	0.0
Blood Red Count	0.1	1.0	2.4	-1.0	1.5	-0.0	0.8	-1.5	-1.5	-0.5	0.5	0.8
Blood White Count	0.1	1.1	3.2	0.3	0.8	-0.3	0.9	-0.6	-0.8	1.8	-1.8	0.9
Heel T-Score	0.3	2.0	4.5	-1.6	0.4	1.3	-2.0	-1.4	-1.2	0.9	2.1	1.1
BMI	0.3	1.7	8.8	-0.7	-1.2	-0.7	-0.0	0.3	0.6	3.0	-1.4	-1.1
Height	0.1	1.7	5.8	0.5	0.9	-0.8	0.9	-1.1	-1.1	2.1	2.4	0.6
Waist Hip Ratio (WHR)	0.5	2.3	7.6	1.9	1.1	1.2	2.0	-0.9	-1.1	0.4	1.0	2.8
Systolic Blood Pressure	3.3	16.6	46.6	-6.0	-6.1	-1.0	-3.6	-2.8	-2.0	1.4	-6.8	-1.1
Smoking Status	0.8	1.8	7.3	-2.7	1.0	2.4	-0.9	-0.6	-0.6	0.2	-0.9	-0.2
Allergy or Eczema	1.2	3.0	8.4	0.5	0.8	0.2	-2.9	-2.5	-2.5	-0.0	-0.0	2.4
Cardiovascular Disease	2.9	9.5	27.6	-4.3	-4.6	0.7	-3.0	-2.4	-1.8	0.1	-5.3	0.1
Hypothyroidism (self reported)	0.2	0.5	1.7	-0.7	0.1	1.3	-0.3	-0.9	-0.9	0.5	-0.2	-0.0
Respiratory disease	0.2	0.5	1.8	1.0	0.4	-0.0	-0.3	0.1	-0.0	-0.9	1.3	0.5
Type 2 Diabetes (T2D) (2018)	0.6	1.1	4.1	0.2	-1.2	-1.2	2.0	0.5	0.7	1.4	0.1	-0.4
Lung FEV1/FVC ratio	0.2	1.1	2.8	0.4	-0.4	1.1	1.1	1.4	1.3	-0.5	-0.6	-1.7
Lung FVC	0.4	1.9	4.8	-1.5	-1.2	-1.8	1.1	0.4	0.7	1.4	-1.5	-2.2
Neuroticism	0.9	2.1	5.0	-0.9	1.6	1.5	0.1	-2.2	-2.2	-1.2	0.8	1.4
Chronotype (morning person)	0.7	1.6	5.6	1.8	1.4	0.5	0.6	-0.0	-0.1	-0.1	2.4	1.7
Hair Pigment	0.0	0.5	1.2	1.1	0.8	0.6	0.7	0.8	0.8	-0.3	0.4	0.3
Tanning	0.1	0.6	1.5	-0.8	-0.7	-1.2	0.1	-0.8	-0.8	0.5	-0.9	0.8
Hand grip strength (left)	0.3	0.9	3.5	-1.3	-0.8	0.5	0.0	0.3	0.4	1.3	0.5	-1.9
Number of treatments/medications taken	2.2	4.0	16.0	-1.9	-2.4	1.9	-1.4	-1.7	-1.5	-0.1	-4.0	0.8
Average weekly spirits intake	0.4	0.5	2.4	-0.5	-0.5	0.5	0.9	-0.2	-0.3	-1.6	0.2	0.1
Sensitivity / hurt feelings	0.5	0.9	3.0	-0.9	0.5	-0.0	0.1	-1.7	-1.7	-0.0	0.5	0.9
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.1	-0.8	-0.1	-0.6	-0.9	-0.9	-0.9	1.1	-0.3	0.5
Hearing difficulty/problems: Yes	0.3	0.5	2.1	0.1	0.1	-1.5	1.0	-0.5	-0.7	-0.5	0.0	-0.4
Relative age of first facial hair	0.7	1.5	4.4	1.7	2.1	-0.6	0.4	1.5	1.5	0.1	1.0	-0.2
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.0	0.9	0.1	1.4	1.1	-0.9	-0.7	-1.0	0.1	0.9
Ever used hormone-replacement therapy (HRT)	1.0	1.3	3.7	0.2	1.4	0.6	-0.2	-1.5	-1.5	-0.9	0.1	1.9
Ever had hysterectomy (womb removed)	1.2	1.3	5.4	-0.9	-0.8	-0.1	-2.3	-0.1	0.0	1.1	-1.9	-0.2
Systolic blood pressure, automated reading	2.0	5.8	14.4	-3.0	-2.8	-2.6	-2.2	-2.4	-1.9	0.1	-3.8	0.4
Eye problems/disorders: Diabetes related eye disease	1.5	1.6	3.6	-1.9	-1.1	-1.2	-1.5	-1.5	-1.3	1.3	-0.7	0.4
Angina	0.2	0.3	0.9	-0.2	-0.6	0.6	-0.2	-0.1	-0.0	0.9	-0.9	-0.2
Medication for hormone replacement therapy	1.2	1.4	5.1	2.2	1.5	-0.7	0.3	-0.3	-0.5	-0.6	0.9	1.6
Vitamin and mineral supplements	1.0	1.4	4.1	-2.0	-1.2	1.2	-0.8	0.1	0.3	-0.8	-1.6	-1.4
Supplements: Zinc	0.6	0.7	3.9	0.4	-0.6	-2.0	0.9	0.2	0.2	0.7	-0.1	0.5
Medication: Co-codamol	0.9	1.0	4.4	0.2	-0.5	2.1	1.2	-0.2	-0.1	1.4	-0.1	1.1
Medication: Metformin	1.1	1.5	5.6	-0.2	-1.8	-2.4	1.7	-0.0	0.2	1.3	0.0	-0.1
Diabetes (father)	1.3	1.6	5.5	-0.7	1.2	-1.3	0.7	-1.3	-1.5	-0.4	2.3	0.4
Diabetes (mother)	0.6	0.8	2.5	1.1	-0.7	0.9	0.4	-0.5	-0.5	1.1	0.4	1.6
Severe depression (siblings)	0.5	0.6	2.0	0.4	0.6	0.6	-0.7	-0.2	-0.2	-1.0	1.4	1.1
Pack years adult smoking proportion	0.2	0.3	1.4	0.6	0.3	-0.6	0.2	0.6	0.7	-1.2	0.2	-0.2
Impedance of leg (right)	0.6	3.1	5.5	2.3	2.1	0.6	2.2	1.6	1.3	-1.6	2.4	0.9
Leg fat-free mass (left)	0.3	1.7	4.1	-0.5	-0.7	-1.0	-1.9	-1.8	-1.4	2.0	-0.9	-0.0
Trunk fat percentage	0.1	0.6	2.0	1.4	0.7	-0.4	1.1	0.5	0.6	0.9	0.2	0.3
Hand grip strength (right)	0.2	0.5	1.6	-0.4	-0.4	-0.7	0.6	-0.5	-0.4	0.7	1.3	-0.7
Townsend deprivation index at recruitment	0.5	0.7	2.2	0.4	-1.3	-0.2	-0.8	-0.1	-0.1	-1.5	-1.0	0.2
Current tobacco smoking	0.7	1.2	7.3	-2.7	0.5	1.2	-0.2	0.1	0.2	0.1	-0.7	-1.0
Average weekly fortified wine intake	0.9	1.1	2.9	-1.7	0.3	0.8	-1.2	-1.4	-1.3	0.3	0.6	0.6
Maternal smoking around birth	2.1	3.0	7.6	-1.3	-2.7	-0.2	0.9	1.9	2.1	0.3	-1.7	-2.3
Fed-up feelings	0.7	1.2	3.6	-0.3	0.5	0.6	-0.5	-1.9	-1.8	0.1	-0.1	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	1.0	0.0	-0.6	1.0	-0.7	-0.5	-0.5	0.0	-0.8	1.0
Relative age voice broke	0.7	1.0	3.1	0.0	1.7	-0.2	0.2	0.9	0.9	-0.2	1.8	-1.1
Taking other prescription medications	1.0	1.6	5.8	-0.1	-1.5	2.4	-0.1	-0.7	-0.7	0.6	-2.2	0.3
Age when periods started (menarche)	1.2	3.0	7.5	0.7	2.7	0.4	-2.7	-1.4	-1.8	-0.2	2.0	1.4
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	6.8	-1.4	-0.8	-0.4	-2.6	0.2	0.1	0.8	-1.4	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	5.2	0.8	-2.3	0.9	0.7	1.6	1.7	-0.4	-0.9	-2.0
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	5.6	1.4	1.7	0.3	0.1	0.3	0.0	-0.4	2.4	0.4
Qualifications: CSEs or equivalent	0.4	0.5	2.8	1.7	0.8	0.4	0.5	-0.2	-0.3	0.0	0.3	0.5
Serious illness, injury or assault to yourself	2.0	2.4	5.0	-1.2	1.3	1.1	-0.6	-2.2	-2.2	-2.1	-0.2	1.6
High blood pressure	3.4	9.4	26.3	-4.2	-4.4	-0.2	-2.5	-3.0	-2.4	-0.6	-5.1	0.3
Hayfever, allergic rhinitis or eczema	0.6	1.3	5.1	0.7	0.9	-0.1	-2.2	-1.3	-1.3	0.7	-0.1	1.2
Multivitamins +/- minerals	0.5	0.6	2.6	1.6	0.4	-0.8	0.8	0.0	-0.2	0.2	1.0	0.7
Stomach or abdominal pain in last month	2.3	2.8	5.9	2.3	2.4	0.8	0.7	-0.8	-0.9	0.3	2.4	2.4
Supplements: Glucosamine	0.8	1.1	2.8	1.5	1.2	-0.6	1.3	0.4	0.3	-1.7	0.9	-0.3
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	4.7	0.2	1.5	0.8	0.5	-0.9	-1.0	2.2	1.0	0.8
Medication: Atenolol	3.1	3.9	9.1	-2.1	-2.4	-0.0	-3.0	-2.0	-1.7	-0.1	-2.8	0.7
Medication: Levothyroxine sodium	0.3	0.5	1.3	0.2	-0.2	0.4	-0.1	1.1	1.0	-0.6	-0.7	-1.1
Sitting height	0.1	0.6	1.8	-0.9	-0.7	0.4	-1.3	-1.0	-0.8	0.3	-0.4	-0.8
Chronic bronchitis/emphysema (father)	0.5	0.6	2.6	1.6	-0.5	0.6	0.2	-0.2	-0.1	-0.2	0.4	1.2
High blood pressure (mother)	2.4	3.4	10.2	-1.6	-2.6	0.5	-2.6	-0.7	-0.3	2.0	-3.2	-0.2
Body mass index (BMI)	0.2	0.8	3.1	-0.5	-0.6	-0.4	-0.5	-0.4	-0.1	1.8	-1.5	-0.6
Impedance of leg (left)	0.7	3.6	9.4	2.2	1.6	0.3	3.1	2.0	1.6	-1.7	2.3	0.5
Leg predicted mass (left)	0.3	1.8	4.3	-0.6	-0.8	-1.0	-2.0	-1.8	-1.4	2.1	-0.9	-0.1
Trunk fat mass	0.1	0.4	1.4	1.0	0.4	-0.6	0.5	-0.3	-0.2	1.2	-0.2	0.2
Waist circumference	0.2	0.6	1.4	0.7	0.1	-0.7	0.4	-1.0	-0.8	1.2	-0.6	0.7
Number of incorrect matches in round	0.1	0.2	0.7	-0.7	-0.5	-0.2	-0.1	-0.3	-0.4	-0.9	-0.1	0.3
Past tobacco smoking	0.8	1.4	4.1	2.0	0.7	-1.7	0.0	0.8	0.9	-0.9	1.7	0.5
Alcohol usually taken with meals	1.2	1.9	4.9	-1.0	-1.9	-1.0	-1.1	-1.0	-0.7	-2.0	-2.2	0.2
Nervous feelings	0.3	0.6	2.3	0.1	-0.8	1.5	-0.0	0.4	0.4	-1.2	-0.8	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	3.2	0.5	0.7	0.3	-0.2	-0.9	-0.9	0.9	1.1	1.8
Hearing difficulty/problems with background noise	0.5	0.8	4.4	0.4	-0.9	0.7	-0.7	0.2	0.2	0.9	-2.1	-0.5
Hair/balding pattern: Pattern 2	1.0	1.2	3.3	1.8	-0.5	0.3	1.2	1.5	1.6	-0.1	-0.9	0.3
Had menopause	0.6	0.8	1.4	-0.6	1.2	0.6	1.0	-0.9	-0.9	-1.0	0.0	1.2
Had other major operations	0.8	0.9	1.9	-1.4	-1.1	0.3	-0.1	-1.1	-1.0	1.1	-1.4	0.2
Forced vital capacity (FVC)	0.1	0.6	2.2	-0.5	-0.5	-1.5	0.4	-0.1	0.1	0.8	0.1	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.8	0.4	-1.7	1.2	0.3	1.1	1.3	-0.7	-0.0	-1.4
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.0	-1.1	-0.7	0.5	-1.7	-0.9	-0.8	-0.5	-1.0	0.1
Qualifications: None of the above	1.6	3.5	8.3	-1.9	-1.0	0.1	-2.5	-2.4	-2.0	0.0	-2.9	1.5
Financial difficulties in last 2 years	0.5	0.7	2.6	-0.2	0.3	0.3	-0.1	0.8	1.0	1.6	0.2	-1.2
Mouth/teeth dental problems	0.2	0.2	0.7	-0.2	0.2	-0.8	-0.1	0.7	0.7	0.1	0.3	-0.6
Heart attack	0.7	0.9	4.3	-0.1	-1.4	0.8	-0.6	-0.2	-0.0	-0.6	-2.1	-0.4
Allergy	0.6	1.5	7.6	-1.1	-0.3	0.1	2.8	1.0	1.1	-0.9	0.6	-1.1
Pain all over the body in last month	0.6	0.6	1.7	-0.9	-0.4	1.3	1.3	0.4	0.3	0.7	-0.7	-0.5
Diabetes (self-reported)	0.5	0.7	1.9	0.6	-1.2	-1.4	1.1	0.0	0.3	1.0	0.6	0.2
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	5.6	-1.2	-1.3	-0.4	-1.4	-0.0	-0.0	0.6	-2.4	-0.7
Medication: Ramipril	2.5	3.2	10.1	-2.3	-3.1	1.1	-0.1	-0.2	0.1	-0.6	-3.2	-1.5
Medication: Simvastatin	0.8	1.2	3.3	1.7	-0.6	0.4	1.8	1.4	1.3	-0.6	0.1	0.1
Fluid intelligence score	1.5	3.1	6.8	1.0	-1.1	-1.2	1.7	2.6	2.6	-0.3	1.7	-2.2
Illnesses of siblings	0.5	0.7	2.2	0.6	1.0	0.2	0.7	-0.1	-0.2	1.4	1.5	0.2
Neuroticism score	0.6	1.3	3.3	-1.0	0.6	1.4	-0.3	-1.8	-1.8	-0.9	0.2	0.9
Weight	0.2	0.8	2.6	-0.2	-0.3	-0.7	-0.5	-1.3	-1.0	1.6	-0.8	-0.2
Impedance of arm (right)	0.8	3.7	7.5	2.6	1.9	0.5	2.3	2.2	1.8	-1.3	2.7	0.6
Arm fat percentage (right)	0.1	0.5	1.8	1.0	0.3	-0.1	0.8	0.6	0.7	1.3	-0.5	-0.5
Trunk fat-free mass	0.5	2.7	8.5	-1.6	-0.9	-0.3	-1.9	-2.9	-2.6	0.9	-1.1	-0.0
Hip circumference	0.1	0.5	2.1	-0.4	-0.0	-0.9	-0.7	-0.7	-0.5	1.4	-0.3	-0.4
Time employed in main current job	0.8	1.0	3.4	-0.2	-0.8	0.7	-0.6	-1.1	-1.0	0.2	-1.2	1.8
Alcohol intake versus 10 years previously	1.0	1.5	2.9	0.2	-1.5	1.7	0.2	1.5	1.7	1.5	-0.8	-0.2
Father’s age at death	2.6	3.5	11.9	2.6	2.3	-0.4	2.6	-0.2	-0.4	-0.5	3.5	0.7
Worrier / anxious feelings	0.3	0.5	1.5	0.9	0.8	1.2	0.8	0.4	0.2	-0.8	0.4	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.3	0.6	0.6	-0.0	-0.1	-0.4	-0.4	0.8	1.0	1.1
Falls in the last year	2.0	2.7	4.8	1.1	2.2	-1.5	-1.8	-1.6	-1.6	-1.4	1.0	2.1
Hair/balding pattern: Pattern 3	0.1	0.2	0.6	-0.5	0.0	-0.8	0.3	-0.1	-0.3	-0.5	0.6	0.0
Number of live births	1.2	1.7	6.4	0.7	0.8	0.1	-1.1	-1.7	-1.8	-0.1	-0.7	2.5
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	1.4	-0.1	-0.9	-0.9	0.6	0.1	0.3	1.1	-0.3	-1.2
Pulse rate	0.6	1.0	3.1	-1.8	-0.3	-0.2	0.1	0.3	0.2	-0.1	-1.6	-1.8
Happiness	1.1	1.3	2.9	-0.9	0.5	-0.4	-1.1	-1.6	-1.7	-1.1	0.4	1.4
Noisy workplace	1.9	2.3	5.5	-2.4	-1.5	-0.3	-1.3	1.0	1.0	0.8	-1.7	-2.3
Qualifications: A levels/AS levels or equivalent	1.6	3.5	8.5	-0.2	-2.0	-1.4	1.8	2.6	2.6	1.1	-0.1	-2.9
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	1.3	-0.3	-0.7	-1.1	0.6	-0.2	-0.1	-0.4	-0.9	-0.1
Mouth/teeth dental problems: Dentures	0.9	1.5	3.7	-1.9	1.5	0.1	-0.2	-1.7	-1.7	0.4	0.1	1.0
Asthma	0.1	0.3	0.8	0.9	0.0	0.5	-0.7	0.5	0.4	0.3	0.4	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.5	-0.1	-0.4	0.4	-0.6	0.2	0.2	-1.0	-1.2	-0.4
Medication: Cholesterol lowering	0.2	0.3	1.3	-0.7	-0.1	1.1	0.2	0.2	0.1	-0.4	-0.9	-0.4
Depression (self-reported)	1.3	1.6	3.7	-1.9	-1.1	0.9	-1.9	-0.6	-0.2	0.8	-1.9	-0.8
Medication: Lansoprazole	0.7	0.8	5.0	1.0	-0.4	-0.5	0.9	-0.3	-0.4	-2.2	0.4	0.2
Prospective memory result	1.1	1.4	3.3	0.5	1.3	-1.2	-0.9	-1.2	-1.2	-1.8	0.6	1.3
Lung cancer (father)	1.7	2.0	5.7	0.4	0.8	0.3	-1.5	-1.9	-1.9	-1.1	-0.5	2.4
Illnesses of mother	3.4	4.2	12.4	1.8	1.9	-2.2	0.8	1.3	1.0	-3.5	3.3	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	2.4	0.1	-1.2	-1.3	0.2	0.1	0.4	1.6	-0.3	-1.1
Pulse wave Arterial Stiffness index	0.5	0.6	1.7	0.2	-1.3	0.3	-0.8	-0.8	-0.9	-0.3	-0.5	0.9
Impedance of arm (left)	0.9	4.3	8.7	2.9	1.7	0.2	2.4	2.7	2.3	-0.9	2.7	0.4
Arm fat mass (right)	0.1	0.5	3.0	0.2	-0.2	-0.2	-0.1	-0.4	-0.2	1.7	-0.9	-0.4
Trunk predicted mass	0.5	2.7	8.9	-1.5	-0.8	-0.2	-1.9	-3.0	-2.6	1.0	-1.0	0.0
Standing height	0.1	1.4	3.4	0.5	0.8	-0.7	0.3	-1.9	-1.8	0.1	1.9	1.1
Length of working week for main job	1.2	1.3	5.6	0.4	-2.4	-1.1	-1.7	0.0	0.1	0.6	-1.1	-0.1
Exposure to tobacco smoke at home	0.5	0.5	1.3	-0.3	-0.6	0.5	0.0	-1.1	-1.0	0.2	-1.0	0.8
Breastfed as a baby	0.5	0.7	2.0	-1.4	-1.1	0.2	-0.6	-1.0	-0.8	0.4	-0.4	-0.5
Tense / ‘highly strung’	0.6	1.0	2.3	0.0	1.3	-0.3	0.3	-1.4	-1.5	-0.7	1.1	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	0.9	-0.6	0.4	1.0	0.7	-0.7	-0.8	0.0	0.2	-0.4
Hair/balding pattern: Pattern 4	0.5	1.2	4.4	-2.1	1.0	1.8	0.0	-0.6	-0.4	0.8	0.3	-0.9
Birth weight of first child	1.3	2.4	6.4	-0.4	-0.2	-1.6	2.5	1.6	1.8	1.2	-1.0	-1.9
Peak expiratory flow (PEF)	0.2	0.4	1.7	0.7	-0.1	-1.3	0.2	-0.1	0.1	0.8	-0.3	-0.5
Pulse wave reflection index	1.1	1.4	3.1	-0.6	-1.0	0.8	-1.2	-1.8	-1.7	0.2	0.5	1.7
Ever highly irritable/argumentative for 2 days	0.8	0.9	4.7	-2.2	-1.3	0.9	-0.2	-0.4	-0.3	-0.1	-0.9	-0.2
Loud music exposure frequency	0.7	0.7	3.7	-0.5	0.2	0.9	0.1	-0.6	-0.5	-1.1	-1.9	-0.4
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.6	-0.6	0.1	0.8	-0.2	-0.6	-0.7	0.8	-0.4	-0.3
Mouth/teeth dental problems: Bleeding gums	1.1	1.5	5.4	0.1	-1.2	2.3	-0.9	-0.3	-0.2	-0.5	-2.3	-0.3
Blood clot in the leg (DVT)	0.5	0.6	1.1	-0.7	-0.7	0.3	-0.8	-1.1	-1.0	1.0	-0.2	0.6
Medication: Paracetamol	3.0	5.0	14.2	1.7	2.8	1.4	-1.8	-2.4	-2.5	0.1	1.6	3.8
Headache pain in last month	0.8	1.3	3.2	0.3	0.0	-0.0	-1.8	-1.8	-1.8	0.2	-1.2	0.9
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	9.8	3.1	2.2	-1.1	0.7	0.7	0.5	0.9	2.4	0.6
Glaucoma (self-reported)	1.6	1.9	5.8	-2.4	-1.2	0.2	-1.7	-1.1	-0.9	-0.2	-2.3	0.1
Gout (self-reported)	0.6	0.8	1.9	-0.3	-0.9	1.4	0.9	-1.2	-1.1	-0.1	-0.6	0.6
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.7	-0.8	-0.3	0.4	-0.4	-0.3	-0.3	-0.5	-0.1	-0.5
Medication: Amlodipine	2.9	4.1	11.0	-2.4	-3.3	-0.3	-3.0	-0.5	0.0	-0.3	-3.2	-0.5
Medication: Ventolin 100micrograms inhaler	1.3	1.7	6.0	-1.3	-1.6	-0.9	-1.9	-0.1	-0.0	0.2	-2.5	0.4
Birth weight	0.7	1.5	3.4	1.5	-0.5	1.4	1.2	1.8	1.9	0.4	-0.5	-0.9
Chronic bronchitis/emphysema (mother)	0.5	0.6	3.0	-1.2	0.2	0.6	-0.1	0.2	0.1	1.7	-0.0	-0.8
High blood pressure (siblings)	0.9	1.3	3.7	-1.3	-1.0	-1.9	-1.4	-0.8	-0.5	0.6	-1.2	0.5
Forced vital capacity (FVC), Best measure	0.1	0.5	2.2	0.1	-0.6	-1.5	0.1	-0.1	0.1	0.9	0.6	-0.7
Body fat percentage	0.1	0.5	1.9	1.4	0.5	-0.5	0.9	0.5	0.6	0.9	-0.2	0.1
Leg fat percentage (right)	0.1	0.4	0.9	0.8	0.9	-0.4	0.9	0.1	0.2	0.9	-0.3	0.3
Arm fat-free mass (right)	0.5	2.7	8.2	-1.0	-0.6	-0.8	-2.0	-2.9	-2.5	1.5	-1.0	0.6
Exposure to tobacco smoke outside home	1.2	1.7	4.2	0.7	-1.4	-0.3	0.7	1.6	1.5	-1.4	0.9	-2.1
Comparative body size at age 10	0.2	0.6	1.5	-0.7	-1.2	0.4	0.2	0.8	0.7	1.1	-0.0	-1.1
Number of full brothers	0.3	0.4	1.0	0.7	-0.3	-1.0	-0.3	0.9	0.9	-0.3	-0.4	-0.7
Worry too long after embarrassment	0.1	0.2	0.5	-0.5	-0.7	-0.6	0.1	0.4	0.5	-0.2	-0.2	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	7.7	0.2	1.3	0.6	0.6	-1.4	-1.3	-0.2	1.3	2.8
Wheeze or whistling in the chest in last year	0.4	0.8	3.3	-1.8	1.0	0.5	-0.4	-0.8	-0.9	0.6	0.8	-0.0
Number of children fathered	1.3	1.4	5.6	-1.3	-2.4	-0.7	-0.0	0.6	0.8	-0.8	-1.1	-1.6
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.8	-1.0	-0.8	-0.2	-0.1	0.8	0.9	-1.1	0.1	-1.7
Age at first live birth	0.3	0.5	1.9	1.4	0.4	0.2	-0.3	0.1	0.1	0.7	1.3	0.3
Pulse wave peak to peak time	0.5	0.6	1.7	-0.2	1.3	-0.4	0.7	0.7	0.8	0.3	0.7	-1.0
Health satisfaction	0.9	1.2	5.1	-0.4	-1.3	2.3	0.7	-0.2	-0.0	0.9	-1.6	0.1
Shortness of breath walking on level ground	2.1	2.5	6.3	-1.5	0.1	1.4	-0.2	-2.3	-2.2	1.2	-0.1	2.5
Qualifications: College or University degree	1.1	3.4	7.7	0.9	-0.6	-2.8	1.0	2.5	2.4	-0.2	1.3	-2.6
Eye problems/disorders: None of the above	2.0	2.3	5.7	2.4	0.3	1.3	2.1	1.5	1.3	0.7	2.0	-0.8
Mouth/teeth dental problems: Loose teeth	1.0	1.2	3.8	-0.3	-0.3	1.4	0.4	1.0	1.1	0.9	-1.9	-1.3
Emphysema/chronic bronchitis	1.2	1.3	3.4	-1.3	0.3	-0.3	-1.8	-1.4	-1.6	-1.1	0.0	1.1
Medication for pain relief, constipation, heartburn	1.7	2.9	7.5	-0.5	-1.3	-1.3	1.1	2.6	2.7	-0.0	0.5	-2.7
Neck or shoulder pain in last month	0.5	0.7	2.3	-0.1	0.4	0.8	-0.6	-1.1	-1.1	-0.5	0.7	1.5
Medication: Blood pressure	3.2	5.7	15.7	-3.9	-4.0	0.8	-2.2	-1.1	-0.7	-1.0	-3.4	-0.5
Angina (self-reported)	0.3	0.4	1.5	-0.0	-0.7	0.9	-0.2	0.1	0.1	0.8	-1.2	-0.1
Migraine (self-reported)	0.8	1.0	3.4	1.8	-0.5	-0.7	0.3	-0.9	-0.9	-0.6	-1.2	1.1
Medication: Ibuprofen	0.6	0.7	2.8	0.1	-0.8	0.9	-0.5	0.4	0.5	-1.0	-1.7	-0.5
Medication: Allopurinol	0.4	0.5	2.0	-0.9	-1.4	0.1	-0.1	-1.0	-0.8	-0.2	-0.3	0.1
Medication: Omeprazole	0.4	0.4	1.2	0.4	0.8	1.1	-0.6	-0.4	-0.4	1.0	-0.4	0.5
Medication: Seretide 50 evohaler	0.7	0.8	1.8	-0.7	-0.8	-0.4	1.0	-1.3	-1.3	0.9	0.7	0.8
Mean time to correctly identify matches	3.4	6.4	10.0	-2.6	1.4	1.8	-3.0	-3.1	-3.2	-2.1	-2.1	2.8
Heart disease (mother)	2.7	3.3	16.4	-0.8	-1.0	2.5	1.3	-0.4	-0.2	4.1	-1.8	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.0	-0.1	-0.1	-1.0	-0.8	-0.3	-0.4	-1.0	0.6	0.5
Whole body fat mass	0.1	0.5	2.0	1.0	-0.0	-0.8	0.4	-0.1	0.1	1.4	-0.6	-0.1
Leg fat mass (right)	0.1	0.5	2.2	0.7	0.2	-1.0	0.2	-0.2	-0.0	1.5	-0.6	-0.2
Arm predicted mass (right)	0.5	2.6	7.8	-1.2	-0.6	-0.6	-1.8	-2.8	-2.4	1.6	-1.1	0.4
Pulse rate, automated reading	0.3	0.9	2.1	-0.1	-0.4	1.2	0.5	0.9	0.9	0.7	-1.3	-1.5
Alcohol intake frequency.	0.6	1.4	5.0	-0.9	-0.5	2.2	-0.6	-0.9	-0.9	1.3	-1.7	0.8
Comparative height size at age 10	0.6	3.1	9.5	-0.3	-0.0	-1.3	-0.2	-3.1	-2.9	0.3	1.1	2.6
Number of full sisters	0.0	0.1	0.2	0.2	0.0	-0.1	-0.1	-0.0	-0.1	-0.4	-0.4	-0.3
Suffer from ‘nerves’	0.6	0.9	2.5	-1.6	0.6	1.5	-0.0	-1.0	-1.0	0.9	-0.2	-0.2
Overall health rating	0.7	1.4	3.1	-0.3	-0.2	1.5	0.4	-1.8	-1.7	1.1	-0.9	1.6
Chest pain or discomfort	0.6	0.8	2.1	1.1	0.4	1.4	1.5	0.6	0.5	-0.8	0.4	0.4
Had major operations	0.4	0.5	1.8	0.4	-1.3	1.2	-0.5	-0.4	-0.3	-0.4	-0.2	0.4
Age at last live birth	0.9	1.3	8.3	2.9	0.5	-0.2	0.4	-0.1	-0.1	-0.7	1.3	0.8
Family relationship satisfaction	0.6	0.8	2.2	-1.5	0.2	-0.6	-0.2	-1.2	-1.2	0.4	0.9	0.7
Leg pain on walking	1.4	1.8	4.5	1.6	1.1	0.9	-1.0	-1.6	-1.6	-0.9	-0.5	2.1
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	4.4	0.1	-0.9	-0.8	0.3	1.7	1.7	1.9	0.3	-2.1
Commuting to job workplace: Car/motor vehicle	1.1	1.3	4.7	0.6	-1.3	-0.2	-2.2	0.5	0.9	-0.4	-1.4	-1.2
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	5.0	2.2	-0.1	-0.4	0.9	1.5	1.4	-0.4	0.5	-0.2
Medication: Aspirin	1.0	1.3	6.6	-1.2	-1.6	-0.4	0.6	-0.4	-0.2	-0.3	-2.6	-0.7
Supplements: Vitamin C	1.8	2.1	6.2	0.7	2.0	-0.5	0.3	-1.3	-1.4	-0.2	2.1	2.5
Knee pain experienced in last month	1.3	2.0	5.5	0.8	2.3	-0.7	-1.6	-1.5	-1.6	-0.4	1.5	1.1
Hypertension (Self-reported)	3.7	10.3	28.9	-4.4	-4.5	0.3	-3.0	-3.0	-2.3	-0.3	-5.4	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	2.5	-0.7	-0.4	-0.8	-0.6	-1.6	-1.6	0.5	-0.6	0.7
Illnesses of father: Heart disease	0.7	1.0	3.6	-1.1	-0.8	1.9	-0.9	0.6	0.6	-1.1	0.0	-1.1
Illnesses of siblings: Diabetes	1.3	1.6	5.1	0.9	-0.2	0.1	2.3	1.6	1.4	-0.9	0.6	-1.5
Smoking status: Previous	0.4	0.6	1.2	-0.5	-0.3	1.1	-0.2	-1.1	-1.1	0.6	-0.7	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	1.7	0.6	-0.2	0.1	-0.5	0.5	0.6	1.3	0.1	-0.3
Whole body fat-free mass	0.4	2.2	6.2	-1.3	-0.9	-0.6	-2.0	-2.5	-2.1	1.3	-1.0	-0.1
Leg fat-free mass (right)	0.3	1.8	4.3	-0.8	-1.2	-1.1	-1.7	-1.6	-1.2	2.1	-1.1	-0.4
Arm fat percentage (left)	0.2	0.9	2.8	1.3	0.2	-0.5	0.7	0.9	1.0	1.7	-0.7	-0.6
Average weekly red wine intake	1.3	1.9	6.9	-1.1	-1.7	-2.6	-1.1	0.2	0.3	-0.6	-1.7	-1.3
Handedness (chirality/laterality): Left-handed	1.3	1.5	8.1	0.0	-0.5	-0.9	1.1	0.7	0.9	2.9	0.7	-1.2
Mood swings	0.6	1.1	3.6	-0.3	0.4	0.0	-0.6	-1.9	-1.7	-0.4	-1.1	1.2
Loneliness, isolation	1.4	1.9	5.1	-2.3	0.6	-0.0	-0.9	-2.2	-2.2	0.9	-0.2	0.7
Long-standing illness, disability or infirmity	1.0	1.5	5.3	-0.3	0.3	2.3	0.4	-1.8	-1.8	0.7	-0.1	1.2
Ever had bowel cancer screening	0.4	0.5	1.9	-0.8	0.1	0.2	0.5	-0.1	-0.3	-1.4	0.8	-0.7
Diabetes diagnosed by doctor	1.0	1.6	5.2	0.0	-2.3	-2.2	1.2	0.5	0.7	1.3	-0.1	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	6.7	1.5	0.0	-0.2	0.1	-1.4	-1.5	0.3	0.1	2.6
Friendships satisfaction	0.6	0.7	1.6	-0.2	0.5	-1.3	-0.9	-0.9	-1.0	-0.7	1.0	0.8
Qualifications: nursing, teaching	0.3	0.5	2.5	1.0	-0.3	0.3	0.7	0.3	0.2	-0.4	1.6	-0.4
Commuting to job workplace: Walk	2.1	2.2	5.9	0.6	-1.7	-1.4	0.8	2.4	2.4	-0.6	-0.1	-1.5
Eye problems/disorders: Cataract	0.7	0.9	2.2	-1.0	-0.0	-1.2	-1.5	-0.5	-0.5	-1.4	-0.1	0.7
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.6	1.9	-0.7	-0.9	1.3	0.0	-0.1	-1.4	1.7	0.5
Medication for cholesterol	2.4	3.7	10.8	2.3	2.7	-0.0	1.9	1.7	1.2	-0.6	3.3	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.5	-0.7	-0.2	1.0	-0.5	0.6	0.6	0.5	-1.6	-0.2
Back pain experienced in last month	1.0	1.4	3.4	0.0	1.2	1.2	-1.6	-1.1	-1.1	1.8	-0.0	1.4
Mineral and other dietary supplements	1.1	1.5	4.0	-0.8	-1.3	1.8	0.2	0.8	0.9	2.0	-1.2	-0.9
Breast cancer (self-reported)	0.5	0.6	2.2	-0.6	-0.5	-1.5	-0.5	-0.2	-0.1	1.4	-0.6	0.2
Asthma (self-reported)	0.1	0.2	0.6	0.7	0.2	0.3	-0.8	0.5	0.4	0.0	0.3	0.2
Osteoporosis (self-reported)	0.7	0.9	3.6	-0.3	-0.0	0.9	-0.6	-0.0	-0.1	-1.9	-1.8	0.5
Osteoarthritis (self-reported)	1.1	1.4	4.3	2.1	0.1	0.6	0.8	1.2	1.4	1.9	-0.4	0.4
Medication: Aspirin	1.0	1.3	5.7	-0.8	-1.8	-0.5	0.8	0.2	0.4	-0.5	-2.4	-1.1
Medication: Gliclazide	1.2	1.4	3.2	1.2	-0.7	-1.1	0.6	1.8	1.8	1.2	0.2	-1.1
Illnesses of father: None of the above (group 1)	2.4	3.0	7.5	2.7	1.0	-1.4	1.2	2.6	2.7	0.6	-0.3	-0.8
Smoking status: Current	0.9	1.4	8.4	-2.9	0.4	1.2	-0.2	0.3	0.4	0.3	-0.8	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.1	0.4	0.4	1.1	-0.4	-0.7	-0.6	-0.6	0.1	0.1
Whole body water mass	0.4	2.4	7.1	-1.3	-0.8	-0.6	-1.9	-2.7	-2.3	1.3	-1.0	0.0
Leg predicted mass (right)	0.3	1.8	4.4	-0.8	-1.3	-1.1	-1.7	-1.6	-1.2	2.1	-1.2	-0.4
Arm fat mass (left)	0.2	0.6	3.3	0.4	-0.3	-0.4	0.2	-0.0	0.2	1.8	-1.2	-0.8
Number of self-reported non-cancer illnesses	2.5	4.4	12.6	-1.8	-2.9	2.9	-0.8	-1.8	-1.4	0.9	-3.5	0.6
Average weekly champagne plus white wine intake	0.6	0.8	2.5	-0.5	-0.1	-1.3	-1.4	-0.3	-0.3	-1.6	0.5	0.5
Miserableness	0.5	0.9	1.8	-0.9	-0.8	1.1	-0.5	-1.3	-1.3	1.2	0.0	0.2
Guilty feelings	1.1	1.7	6.0	-1.8	-0.4	2.1	-0.6	-0.6	-0.6	-2.4	-0.3	-0.2
Wears glasses or contact lenses	0.8	0.9	2.8	0.7	0.7	1.7	0.3	-0.8	-0.8	-1.0	-1.1	1.0
Ever taken oral contraceptive pill	0.4	0.4	1.3	0.4	-0.2	-0.5	-0.9	-0.5	-0.4	0.7	0.2	1.1
Hearing aid user	1.3	1.4	4.8	0.2	1.0	-0.7	-0.4	-2.0	-2.2	0.4	0.1	1.5
Mother’s age at death	0.6	0.8	2.3	-1.2	-0.9	-0.7	-0.4	-1.0	-0.9	-0.1	-1.5	-0.1
Financial situation satisfaction	0.4	0.5	2.6	-1.6	0.2	-0.0	-0.8	-0.6	-0.5	0.3	-0.2	-0.1
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.2	0.1	0.7	-0.0	-1.1	0.3	0.2	-0.8	0.5	-0.6
Commuting to job workplace: Public transport	2.2	2.6	9.3	0.4	0.4	2.4	3.0	1.9	1.7	0.3	1.1	-0.6
Eye problems/disorders: Glaucoma	0.9	1.0	3.4	-0.8	-0.3	-0.3	-1.7	-0.9	-0.8	0.2	-1.8	0.9
Medication: Blood pressure	3.2	6.0	14.5	-3.6	-2.8	0.0	-3.0	-2.4	-1.9	0.7	-3.8	0.4
Pain type(s) experienced in last month: Hip pain	2.3	2.9	6.8	-0.6	2.6	-0.4	-0.4	-2.1	-2.2	0.7	2.3	1.7
Supplements: Fish oil (including cod liver oil)	1.0	1.3	2.3	-1.0	1.3	-1.4	-1.1	-1.5	-1.4	-0.0	0.8	0.7
High cholesterol (Self-reported)	0.2	0.3	0.7	0.4	-0.5	0.5	0.8	0.5	0.7	0.1	-0.6	0.1
Medication: Bendroflumethiazide	2.9	4.3	10.4	-2.7	-2.0	0.3	-3.2	-2.2	-1.9	-1.0	-2.5	1.1
Medication: Paracetamol	3.1	4.8	14.2	1.1	1.8	1.7	-1.6	-2.9	-3.0	0.2	1.0	3.8
Medication: Lisinopril	1.7	2.2	6.5	-1.7	-1.1	-0.7	-2.1	-1.4	-1.3	-0.6	-2.6	0.5
Medication: Atorvastatin	1.8	2.2	7.6	-2.8	-1.9	0.8	-1.2	-0.2	0.1	1.1	-2.1	-1.0
Illnesses of father: High blood pressure	3.0	3.8	11.4	-3.2	-1.4	-1.3	-3.4	-2.0	-1.9	-0.4	-1.0	0.4
Alcohol drinker status: Never	0.8	1.0	5.7	0.6	-0.5	2.4	0.5	-0.5	-0.6	-0.4	-0.2	1.2
Ever smoked	1.5	2.6	6.7	-2.6	-1.8	1.7	0.8	0.5	0.5	0.9	-2.4	-1.8
Basal metabolic rate	0.4	2.0	5.0	-1.0	-0.9	-0.7	-1.8	-2.2	-1.9	1.6	-1.2	-0.1
Leg fat percentage (left)	0.1	0.4	1.8	0.5	0.4	-0.5	1.3	0.1	0.2	0.9	-0.5	0.1
Arm fat-free mass (left)	0.5	2.4	7.0	-1.6	-0.8	-0.2	-1.6	-2.6	-2.3	1.3	-1.3	-0.1
Number of operations (self-reported)	1.1	1.6	3.8	-1.5	-1.7	1.5	-0.6	-1.0	-1.0	1.1	-1.9	-0.4
Average weekly beer plus cider intake	0.2	0.3	2.0	0.3	0.1	1.4	-0.3	0.4	0.5	-0.1	0.2	-0.4
Irritability	0.6	1.0	4.2	-0.9	0.8	2.1	0.6	-1.1	-1.3	-0.5	0.4	-0.0
Risk taking	0.2	0.3	1.0	-0.3	0.3	0.5	-1.0	-0.1	-0.2	-0.2	0.6	0.7
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.4	-0.3	0.8	-0.7	-0.2	-0.8	-1.0	-1.2	0.9	0.8
Fractured/broken bones in last 5 years	1.5	2.0	4.5	-0.5	0.6	-2.0	-0.4	-2.0	-2.1	-1.9	-0.5	0.9
Age started oral contraceptive pill	0.9	1.2	5.4	-0.9	1.1	2.3	-0.1	-0.8	-0.7	-0.3	0.8	1.1
Diastolic blood pressure, automated reading	2.3	7.1	20.2	-2.9	-2.8	-1.5	-3.2	-2.8	-2.3	0.3	-4.5	1.2
Ever depressed for a whole week	0.5	0.6	1.9	-0.6	-0.0	0.1	-1.2	-0.9	-0.7	-0.7	-1.4	0.2
Unable to work because of sickness or disability	1.7	2.2	5.6	-0.1	-0.8	0.5	-1.3	-2.3	-2.4	0.0	-1.7	1.8
Commuting to job workplace: Cycle	0.6	0.8	2.1	1.0	-0.2	-1.3	-1.4	0.6	0.7	-0.9	0.6	0.2
Myopia	0.7	1.1	2.4	-0.0	0.1	1.4	1.5	0.4	0.3	-1.5	-1.2	-1.2
Vascular/heart problems diagnosed by doctor	3.0	8.3	21.4	3.8	3.7	-0.1	2.7	3.2	2.6	0.7	4.6	-0.6
Cholesterol lowering medication	0.8	1.1	4.6	0.0	-2.1	0.3	0.3	0.8	1.0	1.2	-1.5	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	3.2	-0.0	0.2	0.5	-1.8	-0.3	-0.3	1.0	-0.8	-0.1
Pain experienced in last month	1.6	2.6	6.3	-0.3	-1.9	-0.4	2.5	2.1	2.1	-0.9	-0.1	-1.9
Supplements: Calcium	1.1	1.2	5.1	1.9	-0.3	-0.6	-0.9	0.3	0.3	-2.3	-0.8	0.5
Basal cell carcinoma (self-reported)	0.7	0.8	5.0	-0.6	0.2	2.2	0.3	-0.5	-0.5	1.1	0.5	0.1
Heart attack/myocardial infarction (self-reported)	0.6	0.7	3.0	0.0	-1.1	0.9	-0.5	-0.2	-0.1	-0.9	-1.7	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	1.8	-1.1	-0.8	0.4	-0.7	-1.4	-1.3	1.3	-0.7	0.7
Heart disease (siblings)	1.3	1.6	6.2	0.5	-1.1	1.9	-0.4	0.6	0.7	-2.5	-1.2	-0.8
Alcohol drinker status: Previous	0.9	1.1	4.2	-0.6	-0.6	0.7	-1.0	-1.1	-1.0	0.1	-2.0	1.1
Pack years of smoking	0.3	0.4	2.2	0.7	0.4	-0.3	0.3	0.5	0.6	-1.5	0.5	-0.1
Impedance of whole body	1.0	5.0	9.7	3.0	2.3	0.5	2.9	2.4	1.9	-1.5	3.1	0.9
Leg fat mass (left)	0.1	0.5	2.0	0.4	-0.1	-1.0	0.4	-0.2	-0.0	1.4	-0.6	-0.4
Arm predicted mass (left)	0.5	2.7	8.2	-1.7	-0.6	-0.1	-2.1	-2.9	-2.5	1.0	-1.1	0.2